3.013 AMICOR 23

3,013 - AMICOR 23

COVID-19 | ALL TOPICS   The Hard Lessons of Modeling the Coronavirus Pandemic By JORDANA CEPELEWICZ In the fight against COVID-19, disease modelers have struggled with misunderstanding and misuse of their work. They have also come to realize how unready the state of modeling was for this pandemic. Read the article

#De: Academia Sul-Rio-Grandense de Medicina 

Ex Presidente Gilberto Schwartsmann

Recebi o lindo desafio de presidir a recém-criada Bach Society Brazil - à semelhança de suas co-irmãs nos EUA, Países Baixos e outras. Dedica-se à preservação da memória de JS Bach e da música barroca. Planejamos vários recitais didáticos mensais, que serão disponibilizadas pela internet. Amanhã, teremos um deles. Desfrutem, pois valem a pena! 

O Concerto Didático ocorrerá SÁBADO 30 Janeiro - 19h no YouTube da EROICA música

O link direto do concerto será disponibilizado aqui a partir de quinta dia 28/01.

https://linktr.ee/Bachbrasil

 

#From  Medium.com How Falling in Love Physically Changes Our Genes To the immune system, falling in love is like a viral infection. Here’s how it happens. Joe Duncan in Microbial Instincts6 min read

Microbes Sleeping 100 Million Years on the Ocean Floor Have Awakened They even existed before the mighty dinosaurs #Einstein on the Political Power of Art “Nothing can equal the psychological effect of real art — neither factual descriptions nor intellectual discussion.” BY MARIA POPOVA “Tyrants always fear art because tyrants want to mystify while art tends to clarify,” Iris Murdoch wrote in her arresting 1972 address on art as a force of resistance. “Those who tell you ‘Do not put too much politics in your art,’” Chinua Achebe told James Baldwin in their superb forgotten conversation at the close of that decade, “are the same people who are quite happy with the situation as it is… What they are saying is don’t upset the system.” A generation earlier, in the final years of his life, Albert Einstein sat down at his desk in Princeton, New Jersey, to compose a letter of consonant sentiment — a stirring letter of appreciation and assurance to the Polish Jewish artist Si Lewen (November 8, 1918–July 25, 2016), who had just quietly released a staggering work of art and resistance. Si Lewen Born days before Armistice Day, Si was five when he decided to become an artist — or rather (as such elemental self-awarenesses tend to bubble up) when he knew that he was one. In those formative years, his family fled from place to place as the situation for Jews in Europe was darkening by the minute. During a period of refuge in Berlin, while ostracized and bullied at school for being Jewish, he began receiving his first formal art lessons from a disciple of Paul Klee’s. His young imagination and his understanding of the world were being imprinted as much by his refuge in art as by the thickening political atmosphere of animosity that would soon erupt into the world’s grimmest war yet. Charles Stephen3 min read Comentário #From: Starts with a Bang - Ask Ethan: How Does The CMB Reveal The Hubble Constant? We have two ways of measuring the expansion rate. Here’s the harder one. Ethan Siegel10 min read #Rigoberto Chepp Duarte, estaria completando 94 anos hoje, 25/01/2021. Era noivo da Maria José Pires da Rocha, primeira amiga da Valderês quando chegou em Santa Maria. (no link a História mais completa) Foto feita em Porto Alegre, na frente do Colégio Sevigné em 01 de maio de 1950, estando Rigoberto Duarte, noivo da Maira José (ele também faleceu tragicamente num barco que afundou no Guaíba em novembro de 1950, junto com um colega Fernando Mussoi, também de SM). Da esquerda para a direita: João Ignácio Xavier (que foi nosso padrinho de casamento), minha irmã Lia Maria Cechella Achutti, Ieda Costa, a Abigail Duarte, irmã do Rigoberto, ele e a Maria José. EComentário da Abigail: ssa foto em  frente ao Colégio Sevigne, no da 01 de maio de 1950.  Um grupo de jovens da Ação Católica, acompanhara  o Quadro de Nossa Senhora Medianeira levado de Santa Maria a Porto Alegre, por Dom Antônio Reis, Padre Abílio e membros do Círculo Operário por ocasião das comemorações do Dia do Trabalho. Fomos num "carro motor" da Viação Férrea.Lembro que tu tiraste a foto, da qual eu tenho uma cópia. Foi a última fotografia que tirei com o Rigoberto, pois ele faleceu no dia 25 de novembro daquele ano. Um abraço. Abigail # ZH 26/01 E-Book nosso filho, Luiz Eduardo R. A. # Could Amsterdam's New Economic Theory Replace Capitalism? BY CIARA NUGENT READ MORE  # #Claude Shanon  Jimmy Soni Jul 20, 2017·18 min read  V - Photo: Nokia Bell Labs 11 Life Lessons From History’s Most Underrated Genius Insights on work and creativity from the life of mathematician Claude Shannon, the most influential figure you’ve never heard ofBy Rob Goodman and Jimmy Soni, co-auth #ColCORONA: Colchicine Reduces Complications in Outpatient COVID-19  Patrice Wendling January 24, 2021 Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center.  The oral, anti-inflammatory drug colchicine can prevent complications and hospitalizations in patients newly diagnosed with COVID-19, according to a press release from the ColCORONA trial investigators./.../ #From AEON+PSICHÉ How to be a genius I travelled the world and trawled the archive to unearth the hidden lessons from history’s most brilliant # Cancer better map It is time to move beyond tumour sequencing data to identify vulnerabilities in cancers, argue the leaders of the Cancer Dependency Map project at the Wellcome Sanger Institute in the United Kingdom and the Broad Institute in the United States. Their aim is to evaluate every gene and drug perturbation in every possible type of cancer in laboratory experiments, and to make the data accessible to researchers and machine-learning experts worldwide. Nature | 9 min read Cognition and intelligence Essay

3,012 AMICOR 23

#Quand le covid redessine la formation des futurs médecins

FORMATION

Moins de pratique clinique et d’interactions avec les enseignants: les étudiants en médecine entament une 2e année marquée par le Covid-19 avec l’inquiétude d’être moins bien préparés pour l’avenir, si la pandémie continue de chambouler leur formation/.../

#From: Quantamagazine

ABSTRACTIONS BLOG | ALL TOPICS   Secret Ingredient Found to Power Supernovas By THOMAS LEWTON Three-dimensional supernova simulations have solved the mystery of why they explode at all. Read the

#From NATURE

Physicians treat a person with COVID-19 at a hospital’s intensive-care unit in the Czech Republic. (Gabriel Kuchta/Getty) Rogue antibodies might drive severe COVID Evidence is growing that self-attacking ‘autoantibodies’ could be the key to understanding some of the worst cases of COVID-19. One theory is that some people might be predisposed to producing autoantibodies, which then wreak havoc during an infection. Or infections might trigger the production of autoantibodies. In contrast to cytokine storms, which tend to cause systemic, short-duration problems, autoantibodies are thought to result in targeted, longer-term damage. Nature | 10 min read Features & opinion The top physics predictions of all time Theory and experiment often advance hand in hand. But sometimes a theorist makes a stark prediction that shakes our understanding of nature. From James Clerk Maxwell’s electromagnetic-wave-based calculation of the speed of light in air, to Maria Goeppert Mayer’ s anticipation of an entire new row of the periodic table, Physics World picks its ten greatest predictions in physics. Physics World | 15 min read How science can put the SDGs back on track The COVID-19 pandemic has disrupted the Sustainable Development Goals, the United Nations’ flagship plan to end poverty and protect the environment. Researchers need to launch a rapid response to help end the current crisis and get onto a pathway to greater well-being and, eventually, prosperity and environmental sustainability, argues a Nature editorial. “The UN’s science advisers have been given a bigger responsibility than many are ever likely to face,” says the editorial. “Everyone must be ready to work with them and help them succeed.” Nature | 5 min read #Aliens?

Have We Already Been Visited by Aliens? Elizabeth Kolbert, The New Yorker An eminent astrophysicist argues that signs of intelligent extraterrestrial life have appeared in our skies. What’s the evidence for his extraordinary claim?

#An Oral History of Wikipedia, the Web’s Encyclopedia The definitive story of Wikipedia on its 20th anniversary Tom Roston in OneZero23 min read # De minha amiga Ameicana  viúva de John Briscoe According to mr, the best ever.  Conceicao, one of the Es (Expendables) “Hope” is the thing with feathers, That perches in the soul, And sings the tune without the words, And never stops at all. Emily Dickinson  Imagination is the Essence of Life - Conceicao Andrade  You Tube #Iritable Bowels Syndrome - Symptoms and causes - Mayo Clinic www.mayoclinic.org › symptoms-causes › syc-20360016 Oct 15, 2020 — Find out about irritable bowel syndrome symptoms and diagnosis. Often ... IBS is a chronic condition that you'll need to manage long term. ... How irritable bowel syndrome affects you · Spastic colon: What does it mean? ‎Diagnosis and treatment · ‎Mayo Clinic Q & A: Managing... · ‎Irritable bowel syndrome  Síndrome do Cólon Irritável Recomendado pela AMICOR Maria Inês Reinert Azambuja  LINK V  LINK # From NATURE briefing Image of the week This video shows RNA folding as it is made by cellular machinery. The computer model reflects real data collected from RNA experiments in the lab. In your body, folding like this takes place more than 10 quadrillion times a second. The videos surprised researchers by revealing that RNA often folds in surprising ways, such as tying itself into knots and then immediately untying itself to reach its final structure. (Nature | 4 min read) (Watch more of the 4 sec video in the Northwestern University press release) Reference: Molecular Cell paper (Julius Lucks/Northwestern University) #From:Aeon -  Psiche magazine Stories and literature Essay The wisdom of surrender Samuel Beckett turned an obscure 17th-century Christian heresy into an artistic vision and an unusual personal philosophy by Andy Wimbush   #Photographs From the Inauguration of Joe Biden and Kamala Harris READ THE STORY #JANUARY 23, 2021   PUBLISHED BY THE BERGGRUEN INSTITUTE   Visit our homepage here. Weekend Roundup: Agreed-Upon Coercion Lessons from China for climate action.   Nathan Gardels, Noema Editor-in-Chief The ongoing resilience of the Chinese Communist Party when so many other such organizations collapsed after the Cold War still puzzles many in the West. The Chinese scholar Zheng Yongnian calls the Party’s ability to absorb social demands and offer pragmatic responses that have continued to legitimate its rule “inclusive hegemony.” Others have called it “adaptive authoritarianism.” In this way, both stability and the capacity for change have been able to inhabit the same one-party system, cementing its dominance through performance. What has worked so far, however, will fail in the future if heightened coercion replaces adaptation, and hegemony is only enforced from the top instead of legitimated through consensus and inclusion from below. The failure to respond quickly to the COVID outbreak in Wuhan — out of fear by the authorities that stability would be disrupted and the Party’s reputation despoiled — unleashed a global pandemic. The ability to halt its spread at home through decisive and highly coercive measures has made China a mostly safe haven as much of the rest of the world reels before successive surges of viral contagion. This failure and success are two sides of the same coin of China’s system of governance.   Want more Noema Magazine content? Subscribe here. JANUARY 23, 2021 FROM US INAUGURATION DAY 2021 "The Hill We Climb" 5:48 minutes · 2021 US Presidential Inauguration Poet and activist Amanda Gorman recites her poem "The Hill We Climb" at the historic inauguration of Joe Biden and Kamala Harris. Her words call for hope, unity and resilience in a time of division. "While democracy can be periodically delayed, it can never be permanently defeated," she says. "In this truth, in this faith, we trust. For while we have our eyes on the future, history has its eyes on us." (Featured as part of TED's "Best of the Web" series, spotlighting remarkable ideas from around the internet) Watch now » #Artigo meu publicado (ZH) há 12 anos... CERTEZA E PROBABILIDADE... 27 de junho de 2008 N° 15645 Artigo ZERO HORA Incerteza e probabilidade..., por Aloyzio Achutti * Notícias sobre morte súbita de notáveis, como as recentes de um famoso jornalista americano (Tim Russert) e de nossa ex-primeira-dama (Ruth Cardoso), mexem com todo mundo, são motivo de insegurança e muito questionamento sobre médicos e medicina.Gostaríamos que nossos ídolos não fossem tão vulneráveis, que médicos fossem onipotentes e que a medicina não fosse tão limitada. Se pessoas tão famosas estão sujeitas a tais vicissitudes, mais ainda o comum dos mortais... Uma frase famosa do pai da clínica médica moderna (William Osler), no início do século passado, dizia que "medicina é a ciência da incerteza e a arte da probabilidade". As conquistas da ciência, ajudadas pela nossa empáfia, alimentam a fantasia de certeza e infalibilidade. Sabemos hoje das limitações do conhecimento da própria mecânica celeste e das matemáticas. A medicina, baseada na ciência biológica, ainda mais sujeita a variações e incertezas, contrabalança o que lhe falta de ciência com a arte da probabilidade, adquirida na observação do comportamento das coisas naturais. É por isso que, mesmo contando com todo o avanço tecnológico, não se consegue entregar nem o diagnóstico, nem a escolha do tratamento, para uma máquina decidir sozinha. É possível diminuir a surpresa se lembrarmos que em torno de 40% das mortes de causa cardíaca se enquadram nos critérios de subitaneidade (desenlace ocorrendo dentro das primeiras 24 horas do início dos sintomas); que grande parte dos óbitos também não vem de pessoas gravemente doentes, mas de gente com aparência saudável; e que a maior eficácia da medicina radica na prevenção, e não em intervenções em fases avançadas da doença. Não nos deveria causar surpresa - embora nos deixe ainda com mais incertezas - a única verdade imutável: a de que todos nós, como indivíduos, um dia haveremos de morrer, para garantir a biodiversidade e a continuidade da espécie. Um neurobiólogo americano (Robert Sapolsky), estudando estresse provocado pela incerteza, trabalhou com o total desconhecimento do futuro e com o conhecimento prévio do que vai nos acontecer. E chegou à conclusão de que o melhor é ainda viver do modo habitual, com meia verdade, aproveitando o momento atual, tomando as decisões mais adequadas dentro do conjunto do conhecido, deixando de lado o espectro do desconhecido e do futuro. Quando se inverte uma equação estatística, por exemplo, dizendo que 2% morreram ou que 98% sobrevivem - o que dá no mesmo - , nossa reação é diferente. Costumamos nos assustar mais com a incerteza e com a morte do que valorizar as chances (probabilidades) e as conquistas da vida. *Médico