Comparing On-Pump and Off-Pump Coronary Artery Bypass Grafting: Numerous Studies but Few Conclusions: A Scientific Statement From the American Heart Association Council on Cardiovascular Surgery and Anesthesia in Collaboration With the Interdisciplinary Working Group on Quality of Care and Outcomes Research -- Sellke et al. 111 (21): 2858 -- Circulation: "Comparing On-Pump and Off-Pump Coronary Artery Bypass Grafting
Numerous Studies but Few Conclusions: A Scientific Statement From the American Heart Association Council on Cardiovascular Surgery and Anesthesia in Collaboration With the Interdisciplinary Working Group on Quality of Care and Outcomes Research
Frank W. Sellke"
Tuesday, May 31, 2005
Diabetes Hoje
Diabetes Hoje
Informativos da Sociedade Brasileira de Diabetes
Indice de matérias
A Biotecnologia avança e surgem duas novas técnicas
23-05-2005
Reginaldo Albuquerque (AMICOR com grande sucesso na WEB. Grato e Parabéns!) - Comissão científica do site
Nestas últimas semanas, duas novas técnicas de manipulação do genoma, visando à cura de doenças vieram a público.
A primeira, que mereceu maior divulgação nas capas dos principais jornais, revistas e TVs do mundo - denominada de “obtenção de células-tronco personalizadas” -, foi desenvolvida pelo grupo do cientista sul coreano Woo Suk Hwang.
Informativos da Sociedade Brasileira de Diabetes
Indice de matérias
A Biotecnologia avança e surgem duas novas técnicas
23-05-2005
Reginaldo Albuquerque (AMICOR com grande sucesso na WEB. Grato e Parabéns!) - Comissão científica do site
Nestas últimas semanas, duas novas técnicas de manipulação do genoma, visando à cura de doenças vieram a público.
A primeira, que mereceu maior divulgação nas capas dos principais jornais, revistas e TVs do mundo - denominada de “obtenção de células-tronco personalizadas” -, foi desenvolvida pelo grupo do cientista sul coreano Woo Suk Hwang.
Monday, May 30, 2005
Global Burden of Cardiovascular Diseases: Part II: Variations in Cardiovascular Disease by Specific Ethnic Groups and Geographic Regions and Preventio
Global Burden of Cardiovascular Diseases: Part II: Variations in Cardiovascular Disease by Specific Ethnic Groups and Geographic Regions and Prevention Strategies -- Yusuf et al. 104 (23): 2855 -- Circulation
This two-part article provides an overview of the global burden of atherothrombotic cardiovascular disease. Part I initially discusses the epidemiological transition which has resulted in a decrease in deaths in childhood due to infections, with a concomitant increase in cardiovascular and other chronic diseases; and then provides estimates of the burden of cardiovascular (CV) diseases with specific focus on the developing countries. Next, we summarize key information on risk factors for cardiovascular disease (CVD) and indicate that their importance may have been underestimated. Then, we describe overarching factors influencing variations in CVD by ethnicity and region and the influence of urbanization. Part II of this article describes the burden of CV disease by specific region or ethnic group, the risk factors of importance, and possible strategies for prevention.
This two-part article provides an overview of the global burden of atherothrombotic cardiovascular disease. Part I initially discusses the epidemiological transition which has resulted in a decrease in deaths in childhood due to infections, with a concomitant increase in cardiovascular and other chronic diseases; and then provides estimates of the burden of cardiovascular (CV) diseases with specific focus on the developing countries. Next, we summarize key information on risk factors for cardiovascular disease (CVD) and indicate that their importance may have been underestimated. Then, we describe overarching factors influencing variations in CVD by ethnicity and region and the influence of urbanization. Part II of this article describes the burden of CV disease by specific region or ethnic group, the risk factors of importance, and possible strategies for prevention.
César Gomes Victora
O AMICOR César Gomes Victora recebe o prêmio Conrado Wessel de Medicina, ano 2004, no Museu de Arte de São Paulo às 19:30 de hoje, dia 30/05/2005
Pelo seu trabalho a frente do Centro de Epidemiologia, referência Internacional da UFPEL.
Pelo seu trabalho a frente do Centro de Epidemiologia, referência Internacional da UFPEL.
Sunday, May 29, 2005
Prevention and Control, Volume 1, Issue 1, Pages 1-151 (March 2005)
ScienceDirect - Prevention and Control, Volume 1, Issue 1, Pages 1-151 (March 2005)
Editorial
Andy Wielgosz MSc MD PhD FRCPC Corresponding Author Contact Information, E-mail The Corresponding Author
501 Smyth Road, Ottawa, Ont., Canada K1H 8L6
This first issue of the official journal of the World Heart Federation contains all abstracts of the 6th ICPC presentations.
The Editor welcomes contributions for the next issues.
Available online 23 April 2005.
With this issue, the Editorial Board and I wish to welcome you to a new and exciting publishing venture. We believe the timing is right, the need is there and we will occupy an important niche. Prevention and Control, as the official journal of The World Heart Federation, is aimed in particular at those who are concerned about the epidemic of cardiovascular diseases that is reaching the farthest corners of the globe, and also at those who seek to make a difference. The character that this journal develops will depend in large part on the response that we elicit; it is still early.
There are admittedly a few preconceived ideas that I am committed to foster. The focus of the journal will be primarily though not exclusively on issues, which are important to developing countries. Such a focus should not be a surprise given that more than half of the world’s burden of cardiovascular diseases is placed in low and middle income countries and all forecasts indicate an exponential increase over the next two decades. This focus is also aligned with the mission of the World Heart Federation.
There are several key factors that require attention in order to be able to publish excellent articles from and about low and middle income countries. While English is the international language of science, it is not the working language for most in the developing world. We are committed to assisting authors who generate excellent science but have difficulties expressing themselves in English. Particularly for young, emerging scientists we plan to organize a workshop on scientific writing at the upcoming World Congress of Cardiology in Barcelona. Hopefully such workshops will take place at other large meetings as well.
Our reviewers will be encouraged to provide constructive feedback particularly where methodological shortcomings prevent acceptance of manuscripts for publication.
Although the journal will include materials pertaining to both prevention and control of cardiovascular diseases, as its name states, it is my hope that there will be an ever-increasing number of publications addressing prevention. To encourage this will require some innovative approaches to linking research and publishing, perhaps even by creating a forum for dialogue in the planning phase of preventive programmes. I want to be flexible and responsive to suggestions and above all I want the journal to be a valuable resource of knowledge and ideas. This can be achieved by providing a variety of materials including articles reporting the results of experimental research, review articles, informative news and reports particularly of successes in policies and actions in communities, relevant guidelines and others.
Along with the publisher Elsevier and the World Heart Federation, we are committed to the success of this journal. The response of the scientific community and the readership will help guide us and we look forward to your involvement and feedback, which we will survey periodically. Prevention and Control is being launched aptly at the 6th International Conference on Preventive Cardiology in Iguassu Falls, Brazil. The Editorial Board members and I look forward to meeting many potential authors and readers there.
Corresponding Author Contact InformationFax: +613 737 8918
Editorial
Andy Wielgosz MSc MD PhD FRCPC Corresponding Author Contact Information, E-mail The Corresponding Author
501 Smyth Road, Ottawa, Ont., Canada K1H 8L6
This first issue of the official journal of the World Heart Federation contains all abstracts of the 6th ICPC presentations.
The Editor welcomes contributions for the next issues.
Available online 23 April 2005.
With this issue, the Editorial Board and I wish to welcome you to a new and exciting publishing venture. We believe the timing is right, the need is there and we will occupy an important niche. Prevention and Control, as the official journal of The World Heart Federation, is aimed in particular at those who are concerned about the epidemic of cardiovascular diseases that is reaching the farthest corners of the globe, and also at those who seek to make a difference. The character that this journal develops will depend in large part on the response that we elicit; it is still early.
There are admittedly a few preconceived ideas that I am committed to foster. The focus of the journal will be primarily though not exclusively on issues, which are important to developing countries. Such a focus should not be a surprise given that more than half of the world’s burden of cardiovascular diseases is placed in low and middle income countries and all forecasts indicate an exponential increase over the next two decades. This focus is also aligned with the mission of the World Heart Federation.
There are several key factors that require attention in order to be able to publish excellent articles from and about low and middle income countries. While English is the international language of science, it is not the working language for most in the developing world. We are committed to assisting authors who generate excellent science but have difficulties expressing themselves in English. Particularly for young, emerging scientists we plan to organize a workshop on scientific writing at the upcoming World Congress of Cardiology in Barcelona. Hopefully such workshops will take place at other large meetings as well.
Our reviewers will be encouraged to provide constructive feedback particularly where methodological shortcomings prevent acceptance of manuscripts for publication.
Although the journal will include materials pertaining to both prevention and control of cardiovascular diseases, as its name states, it is my hope that there will be an ever-increasing number of publications addressing prevention. To encourage this will require some innovative approaches to linking research and publishing, perhaps even by creating a forum for dialogue in the planning phase of preventive programmes. I want to be flexible and responsive to suggestions and above all I want the journal to be a valuable resource of knowledge and ideas. This can be achieved by providing a variety of materials including articles reporting the results of experimental research, review articles, informative news and reports particularly of successes in policies and actions in communities, relevant guidelines and others.
Along with the publisher Elsevier and the World Heart Federation, we are committed to the success of this journal. The response of the scientific community and the readership will help guide us and we look forward to your involvement and feedback, which we will survey periodically. Prevention and Control is being launched aptly at the 6th International Conference on Preventive Cardiology in Iguassu Falls, Brazil. The Editorial Board members and I look forward to meeting many potential authors and readers there.
Corresponding Author Contact InformationFax: +613 737 8918
INTERNATIONAL ACTION ON CARDIOVASCULAR DISEASE
IHHS Publications
THIS ADDRESS GIVE ACCESS TO ALL DECLARATIONS FROM THE HHS, including a recent publication with a synthesis of all.
THIS ADDRESS GIVE ACCESS TO ALL DECLARATIONS FROM THE HHS, including a recent publication with a synthesis of all.
The Euro Cardio-QoL Project
De: Marcelo Gustavo Colominas [mailto:mgcolominas@hotmail.com]
Enviada em: domingo, 29 de maio de 2005 09:57
Para: cardtran@fac.org.ar; epi-pcvc@fac.org.ar
Assunto: The Euro Cardio-QoL Project
Oldridge, N.; Saner, H.; McGee, H.M.
Vol: 12, Nro: 2, Págs. 87 - 94. Fecha: 1/4/2005
SCChaco
Obesity and the Risk of New-Onset Atrial Fibrillation, November 24, 2004, Wang et al. 292 (20): 2471
JAMA -- Abstract: Obesity and the Risk of New-Onset Atrial Fibrillation, November 24, 2004, Wang et al. 292 (20): 2471
Conclusions Obesity is an important, potentially modifiable risk factor for AF. The excess risk of AF associated with obesity appears to be mediated by left atrial dilatation. These prospective data raise the possibility that interventions to promote normal weight may reduce the population burden of AF.
Conclusions Obesity is an important, potentially modifiable risk factor for AF. The excess risk of AF associated with obesity appears to be mediated by left atrial dilatation. These prospective data raise the possibility that interventions to promote normal weight may reduce the population burden of AF.
Can niacin slow the development of atherosclerosis in coronary artery disease patients already taking statins?
Can niacin slow the development of atherosclerosis in coronary artery disease patients already taking statins? : Nature Clinical Practice Cardiovascular Medicine:
B Greg Brown
"Practice point
In coronary artery disease patients, carotid atherosclerosis progresses significantly in 1 year despite statin therapy to lower LDL cholesterol, but progression is almost halted if extended-release niacin is added to statin"
B Greg Brown
"Practice point
In coronary artery disease patients, carotid atherosclerosis progresses significantly in 1 year despite statin therapy to lower LDL cholesterol, but progression is almost halted if extended-release niacin is added to statin"
Ageing cells may lead to clogged arteries - US team helps explain why even healthy eaters get heart disease.
news @ nature.com�-�Ageing cells may lead to clogged arteries�-�US team helps explain why even healthy eaters get heart disease.: "Some people suffer from heart disease even if they take precautionary measures such as avoiding high-cholesterol foods. Part of the solution to this puzzle is supplied by a team that studied mice with clogged arteries."
Saturday, May 28, 2005
INTERNATIONAL OBESITY TASK FORCE
INTERNATIONAL OBESITY TASK FORCE
Páginas com muito material sobre Obesidade e Síndrome Metabólico. Neste endereço deverá ser colocado um slideshow apresentado por Philip James no último dia da 6a. Conferência de Cardioloogia Preventiva em Foz do Iguaçu.
Pages with a great quantity of material on Obesity and Metabolic Syndrome. In this site must be posted next week a conference from Philip James during the last day of the 6th ICPC.
Páginas com muito material sobre Obesidade e Síndrome Metabólico. Neste endereço deverá ser colocado um slideshow apresentado por Philip James no último dia da 6a. Conferência de Cardioloogia Preventiva em Foz do Iguaçu.
Pages with a great quantity of material on Obesity and Metabolic Syndrome. In this site must be posted next week a conference from Philip James during the last day of the 6th ICPC.
World Heart Federation and sanofi-aventis Join Forces to Encourage Prevention of Cardiovascular Disease
World Heart Federation and sanofi-aventis Join Forces to Encourage Prevention of Cardiovascular Disease
The World Heart Federation and sanofi-aventis have today announced a three-year partnership agreement to address prevention and control of cardiovascular disease. The announcement was made at the World Heart Federation's Sixth International Congress of Preventive Cardiology (ICPC) in Brazil and confirms both organisations' commitment to the prevention of cardiovascular disease across the world.
The World Heart Federation and sanofi-aventis have today announced a three-year partnership agreement to address prevention and control of cardiovascular disease. The announcement was made at the World Heart Federation's Sixth International Congress of Preventive Cardiology (ICPC) in Brazil and confirms both organisations' commitment to the prevention of cardiovascular disease across the world.
Tuesday, May 17, 2005
Risk Factors for Cardiovascular Disease in Homeless Adults -
Risk Factors for Cardiovascular Disease in Homeless Adults -- Lee et al., 10.1161/CIRCULATIONAHA.104.510826 -- Circulation
Methods and Results--Homeless persons were randomly selected at shelters for single adults in Toronto. Response rate was 79%. Participants (n=202) underwent interviews, physical measurements, and blood sampling. The mean age of participants was 42 years, and 89% were men. The prevalence of smoking among homeless subjects (78%; 95% confidence interval [CI], 72% to 84%) was significantly higher than in the general population (standardized morbidity ratio [SMR], 254; 95% CI, 216 to 297). Hypertension, high cholesterol, and diabetes were not more prevalent than in the general population but were often poorly controlled. Homeless men were significantly less likely to be overweight or obese than men in the general population (SMR, 79; 95% CI, 63 to 98). Cocaine use in the last year was reported by 29% of subjects (95% CI, 23% to 36%). CVD was reported by 15% of subjects, fewer than one third of whom reported taking aspirin or cholesterol-lowering medication. According to multiple-risk-factor equations, the median estimated 10-year absolute risk of myocardial infarction or coronary death among homeless men aged 30 to 74 years was 5% (interquartile range, 3% to 9%).
Conclusions--Cardiovascular risk factor modification is suboptimal among homeless adults in Toronto, despite universal health insurance. Multiple risk factor equations may underestimate true risk in this population because of inadequate accounting for factors such as cocaine use and heavy smoking.
Methods and Results--Homeless persons were randomly selected at shelters for single adults in Toronto. Response rate was 79%. Participants (n=202) underwent interviews, physical measurements, and blood sampling. The mean age of participants was 42 years, and 89% were men. The prevalence of smoking among homeless subjects (78%; 95% confidence interval [CI], 72% to 84%) was significantly higher than in the general population (standardized morbidity ratio [SMR], 254; 95% CI, 216 to 297). Hypertension, high cholesterol, and diabetes were not more prevalent than in the general population but were often poorly controlled. Homeless men were significantly less likely to be overweight or obese than men in the general population (SMR, 79; 95% CI, 63 to 98). Cocaine use in the last year was reported by 29% of subjects (95% CI, 23% to 36%). CVD was reported by 15% of subjects, fewer than one third of whom reported taking aspirin or cholesterol-lowering medication. According to multiple-risk-factor equations, the median estimated 10-year absolute risk of myocardial infarction or coronary death among homeless men aged 30 to 74 years was 5% (interquartile range, 3% to 9%).
Conclusions--Cardiovascular risk factor modification is suboptimal among homeless adults in Toronto, despite universal health insurance. Multiple risk factor equations may underestimate true risk in this population because of inadequate accounting for factors such as cocaine use and heavy smoking.
Monday, May 16, 2005
AMNews: May 23/30, 2005. Strokes different in men vs. women ...
AMNews: May 23/30, 2005. Strokes different in men vs. women ... American Medical News:
"Strokes different in men vs. women. Researchers are investigating factors that could cause significant gender disparities in the impact and care received when stroke occurs.
By Victoria Stagg Elliott, AMNews staff. May 23/30, 2005.
The woman had been at a financial planning conference when she suddenly had double vision. It eventually returned to normal. Still, over the next few days, she realized she was having a hard time reading. The problem ultimately led her to the office of Barbara Kostick, MD, a family physician in Freemont, Calif.
This scenario is not usually considered a stroke, but that's exactly what it was -- a small stroke."
"Strokes different in men vs. women. Researchers are investigating factors that could cause significant gender disparities in the impact and care received when stroke occurs.
By Victoria Stagg Elliott, AMNews staff. May 23/30, 2005.
The woman had been at a financial planning conference when she suddenly had double vision. It eventually returned to normal. Still, over the next few days, she realized she was having a hard time reading. The problem ultimately led her to the office of Barbara Kostick, MD, a family physician in Freemont, Calif.
This scenario is not usually considered a stroke, but that's exactly what it was -- a small stroke."
Saturday, May 14, 2005
The fetal origins hypothesis--10 years on -- Eriksson 330 (7500): 1096 -- BMJ
The fetal origins hypothesis--10 years on -- Eriksson 330 (7500): 1096 -- BMJ
Epidemiological studies have largely contributed to our understanding of the natural history of coronary heart disease. Although clinical manifestations of the disease usually become evident in adult life, early signs are recognisable in childhood. The discovery that individuals who develop coronary heart disease grow differently during early life has led to the recognition of new developmental models for the disease. In 1995 David Barker wrote: "The fetal origins hypothesis states that fetal undernutrition in middle to late gestation, which leads to disproportionate fetal growth, programmes later coronary heart disease."1 Now, 10 years later, the importance of events before birth for lifetime health has been confirmed in many populations.2-4 In humans, birth size serves as a marker of the intrauterine environment. Considering that birth size is just one snapshot of the trajectory of fetal growth it is fascinating that long term health outcomes are predicted by the body size of the newborn.
Epidemiological studies have largely contributed to our understanding of the natural history of coronary heart disease. Although clinical manifestations of the disease usually become evident in adult life, early signs are recognisable in childhood. The discovery that individuals who develop coronary heart disease grow differently during early life has led to the recognition of new developmental models for the disease. In 1995 David Barker wrote: "The fetal origins hypothesis states that fetal undernutrition in middle to late gestation, which leads to disproportionate fetal growth, programmes later coronary heart disease."1 Now, 10 years later, the importance of events before birth for lifetime health has been confirmed in many populations.2-4 In humans, birth size serves as a marker of the intrauterine environment. Considering that birth size is just one snapshot of the trajectory of fetal growth it is fascinating that long term health outcomes are predicted by the body size of the newborn.
6TH ICPC-FINAL PROGRAM
PROGRAMA.pdf (application/pdf Object)
Do dia 21 a 25 de maio em Foz do Iguaçu. Programa final.
Do dia 21 a 25 de maio em Foz do Iguaçu. Programa final.
Drug lowers inflammatory markers associated with risk for heart attack
Drug lowers inflammatory markers associated with risk for heart attack: "
'The clinical trial by Hakonarson et al provides an exciting attempt to translate genetic findings to clinical applications. How close clinicians and researchers are to the promised destination of a genome-based diagnostics and therapeutics for MI and stroke remains uncertain. This phase 2 pharmacogenetic trial and its implications must be interpreted with the same degree of caution as with any newly proposed risk factor. Continued research is warranted to replicate the original ALOX5AP association. Careful attention to proper study design will be essential to make future trials credible. … As with nongenetic risk factors, the emerging evidence will need to be carefully and continuously examined to ensure that the benefits outweigh the risks as genomics-based strategies are tested in clinical trials,' concludes Dr. O'Donnell. "
'The clinical trial by Hakonarson et al provides an exciting attempt to translate genetic findings to clinical applications. How close clinicians and researchers are to the promised destination of a genome-based diagnostics and therapeutics for MI and stroke remains uncertain. This phase 2 pharmacogenetic trial and its implications must be interpreted with the same degree of caution as with any newly proposed risk factor. Continued research is warranted to replicate the original ALOX5AP association. Careful attention to proper study design will be essential to make future trials credible. … As with nongenetic risk factors, the emerging evidence will need to be carefully and continuously examined to ensure that the benefits outweigh the risks as genomics-based strategies are tested in clinical trials,' concludes Dr. O'Donnell. "
Wednesday, May 11, 2005
Low-Fat Dairy Reduces Type 2 Diabetes Risk in Men -
Low-Fat Dairy Reduces Type 2 Diabetes Risk in Men - CME Teaching Brief - MedPage Today:
By Katrina Woznicki, MedPage Today Staff Writer. Reviewed by Ethan A. Halm, MD, MPH; Associate Professor in the Departments of Medicine and Health Policy at the Mount Sinai School of Medicine in New York.
# Encourage patients to include low-fat dairy, such as skim milk, into their daily diets. Low fat dairy intake has been found to be associated with a reduced risk for type 2 diabetes.
# Research from the Health Professional Follow-Up study suggests low fat dairy may have favorable effects on body weight, hypertension, and abnormal glucose homeostasis, through which it might help lower type 2 diabetes risk.
# Skim milk appeared to be the most protective. High-fat dairy did not significantly reduce the risk of diabetes."
By Katrina Woznicki, MedPage Today Staff Writer. Reviewed by Ethan A. Halm, MD, MPH; Associate Professor in the Departments of Medicine and Health Policy at the Mount Sinai School of Medicine in New York.
# Encourage patients to include low-fat dairy, such as skim milk, into their daily diets. Low fat dairy intake has been found to be associated with a reduced risk for type 2 diabetes.
# Research from the Health Professional Follow-Up study suggests low fat dairy may have favorable effects on body weight, hypertension, and abnormal glucose homeostasis, through which it might help lower type 2 diabetes risk.
# Skim milk appeared to be the most protective. High-fat dairy did not significantly reduce the risk of diabetes."
Tuesday, May 10, 2005
Suspending Aspirin a Week Before CABG May be Unneeded -
Suspending Aspirin a Week Before CABG May be Unneeded - CME Teaching Brief - MedPage Today: "Review
TEL AVIV, May 9-Halting low-dose aspirin a week before coronary-artery bypass surgery may be counterproductive, suggests a small Israeli study.
Patients who took low-dose aspirin until the day before surgery had shorter ICU stays and quicker recovery times, reported Rabin Gerrah, M.D., and colleagues in the May issue of Chest."
TEL AVIV, May 9-Halting low-dose aspirin a week before coronary-artery bypass surgery may be counterproductive, suggests a small Israeli study.
Patients who took low-dose aspirin until the day before surgery had shorter ICU stays and quicker recovery times, reported Rabin Gerrah, M.D., and colleagues in the May issue of Chest."
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