Sunday, January 16, 2005

Protein's Link to Heart Disease Is a Mystery

The New York Times > Health > Fitness & Nutrition > Protein's Link to Heart Disease Is a Mystery

Acho que eu estava e estou certa, com relação à interpretação da tendência temporal da ocorrência e mortalidade por Doença Isquêmica do Coração nos último século...
"It is proposed that an early 20th-century expansion of a coronary heart disease–prone subpopulation, characterized by high serum-cholesterol phenotype and high case-fatality—which contributed to most of the coronary heart disease cases and deaths during the 1960s—may have been a late result of the 1918 influenza pandemic. .... The extinction of those birth cohorts would result in a relative increase in cases coming from a 2nd subpopulation, which was characterized by insulin resistance and chronic expression of low-grade inflammation markers and was comparatively less vulnerable to die acutely from coronary heart disease."

Azambuja MIR. Spanish Flu and Early 20th-Century Expansion of a Coronary Heart Disease–Prone Subpopulation. Tex Heart Inst J. 2004; 31(1): 14–21. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=15061621

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