(Referência do Reginaldo H. Albuquerque, do Cardiosource.)
The Challenge
Among survivors of myocardial infarction (MI), heart failure frequently ensues as a consequence of cell loss and scar formation in myocardium within the distribution area of the infarct-related artery. In theory, late revascularization might enable hibernating myocardium to recover contractility.1
Cell transplantation may be one means of achieving late myocardial recovery and restoration. Various delivery methods are being evaluated using a variety of cell types (Slide 1), including skeletal myoblasts, endothelial progenitor cells from peripheral blood, and hematopoietic or mesenchymal stem cells derived from fatty tissue or bone marrow.2
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