Therapeutic angiogenesis

E-Journal - Volume 4 - vol4n3:
"Prof. S. Nikol
Munich, Germany
Member of the Nucleus of the ESC Working Group on Interventional Cardiology

Recommended by Marcelo Gustavo Colominas [mgcolominas@hotmail.com]

Therapeutic angiogenesis : Definition
Therapeutic angiogenesis describes an emerging field of cardiovascular medicine whereby new blood vessels are induced to grow to supply oxygen and nutrients to cardiac muscle tha has mostly been rendered ischaemic as a result of progressive atherosclerosis.
Myocardial ischemia is one of the most promising targets of gene therapy, particularly, in the case of refractory angina.
As life expectancy is increasing, patients with angina pectoris refractory to conventional antianginal therapeutics are a challenging problem. Therapeutic angiogenesis may be one way to approach this problem. "/.../