Global Burden of Disease 2005: call for collaborators
Christopher JL Murray a, Alan D Lopez b, Robert Black c, Colin D Mathers d, Kenji Shibuya d, Majid Ezzati e, Joshua A Salomon e, Catherine M Michaud e, Neff Walker c and Theo Vos b
The Global Burden of Disease (GBD) Study was commissioned by the World Bank in 1991 to provide a comprehensive assessment of disease burden in 1990 for 107 diseases and injuries and ten selected risk factors for the world and eight major regions.1 The methods and findings of the original GBD have been widely published2,3 and have stimulated numerous national studies of burden of disease.4–8
The basic philosophy guiding the burden of disease approach is that best estimates of incidence, prevalence, and mortality can be generated through the careful analysis and correction for bias of all available sources of information in a country or region. To assess burden of disease, a time-based measure that combined years of life lost due to premature mortality and years of life lost due to time lived in health states less than ideal health—the disability-adjusted life year, or DALY—was developed. The initial GBD Study represented a major step in the global and regional quantification of the effects of diseases, injuries, and risk factors on population health. Results from the GBD Study have been widely used by governments and non-governmental agencies to inform debates on priorities for research, development, and policy responses./.../
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