June 22, 2011 — In patients with mild cognitive impairment (MCI), the concentration of soluble amyloid precursor protein β (sAPP-β) in cerebrospinal fluid (CSF) may provide an early and specific indicator of incipient Alzheimer's disease (AD), according to research published online June 22 in Neurology.
"This novel biomarker was able to quite accurately identify persons who were about to develop AD in the next few years in a group of individuals with memory deficits," study author Robert Perneczky, MD, of Technical University Munich in Germany, noted in an email to Medscape Medical News./.../
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