The goal of this activity is to provide information on hypertensive patients and discuss issues and trial data as well as how sympathetic activity can be introduced in a patient's management.
Learning Objectives
- Explain how the renal nerves can elevate central sympathetic drive and affect blood pressure control
- Differentiate the role of afferent and efferent renal nerves
- Review current treatments and experimental interventions aimed at the renal nerves to modulate blood pressure
- Describe the scientific rationale behind how ablation of renal nerves can be applied to manage resistant hypertension
Sympathetic nervous system activation has been implicated in the development and progression of systemic hypertension related to a number of different etiologies. The degree of sympathetic nervous system activation correlates with the severity of blood pressure elevation and is more pronounced in the context of comorbid metabolic diseases including diabetes, obesity, and the metabolic syndrome. Dr. Murray Esler discusses the issues related to sympathetic activity pertaining to the pathophysiology of hypertension./.../
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