‘suicide’ messages to cancer cells

DNA nanorobots deliver ‘suicide’ messages to cancer cells, other diseases

February 17, 2012

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Hinged nanorobot opens when target molecules are sensed

Researchers at Harvard University’s Wyss Institute for Biologically Inspired Engineering have developed a nanorobotic device made from DNA that could potentially seek out specific cell targets within a complex mixture of cell types and deliver important molecular instructions, such as telling cancer cells to self-destruct.

Inspired by the mechanics of the body’s own immune system, the technology might one day be used to program immune responses to treat various diseases.

Using the DNA origami method  (complex 3-D shapes and objects are constructed by folding strands of DNA), the researchers created a nanosize robot in the form of an open barrel whose two halves are connected by a hinge./.../