Various brain disorders and associated alterations of pH in different brain regions. The pH is increased in epilepsy (region: temporal lobes), in panic disorder (region: frontal lobes), and in Alzheimer’s disease (region: hippocampus area) and decreased in bipolar disorder (region: frontal lobes). There is no change in pH in Parkinson’s disease patients (during visual-stimulation), white matter damage, schizophrenia, sleep deprivation, or hypoxic hypoxia cases.(Credit: Pravat K. Mandal, et al./Journal of Alzheimer's Disease)
Dr. Pravat K. Mandal and colleagues have developed a non-invasive brain imaging technique that measures specific brain chemical changes in the hippocampus, providing a signature of the early stages of Alzheimer disease.
Key findings in pre-Alzheimer and Alzheimer disease patients in the left hippocampus:
- Increase in pH to the alkaline range.
- Changes in four brain chemicals.
This diagnostic technique requires no blood work or radiation, and can be conducted in less than fifteen minutes, says Dr. Mandal, who is associated with the National Brain Research Center, Gurgaon, India, and Johns Hopkins University School of Medicine. “It may offer hope to Alzheimer’s disease patients and their families.”
No comments:
Post a Comment