Type O Blood x CHD

Type O Blood Carries Lower CHD Risk

By Cole Petrochko, Associate Staff Writer, MedPage Today

Published: August 14, 2012

Reviewed by Robert Jasmer, MD; Associate Clinical Professor of Medicine, University of California, San Francisco

Action Points

• Patients with type A, B, or AB blood are at significantly greater risk for coronary heart disease (CHD) than those with type O blood, a study has found.
• Note that the associations between blood type and CHD risk were not modified by age, physical activity, alcohol consumption, smoking status, or diabetes history in men or women.

Patients with type A, B, or AB blood are at significantly greater risk for coronary heart disease (CHD) than those with type O blood, researchers found.

Two large, prospective cohort studies showed those with a non-O blood type had an age-adjusted hazard ratio of 1.09 (95% CI 1.03 to 1.17, P=0.005) for risk of developing CHD, according to Lu Qi, PhD, of the Harvard School of Public Health, and colleagues.

A meta analysis of an additional six past cohorts also showed a significant pooled relative risk for CHD in patients with non-O blood type of 1.11 (95% CI 1.05 to 1.18, P=0.001), Qi and co-authors wrote in the August 14 issue ofArteriosclerosis, Thrombosis, and Vascular Biology./.../