A step toward a potential anti-aging drug
December 29, 2014
Everolimus, AKA RAD001 (credit: Fvasconcellos/public domain)
According to a new study published in Science Translational Medicine, researchers have tested a potential anti-aging drug called everolimus (AKA RAD001) — an analog (version) of the drug rapamycin (sirolimus)*.
In previous research, rapamycin extended the life span of mice by 9 to 14%, even when treatment was initiated late in life, and it improved a variety of aging-related conditions in old mice, including tendon stiffening, cardiac dysfunction, cognitive decline, and decreased mobility.
These findings raise the possibility that “mTOR inhibitors”* (like rapamycin and RAD001) may have beneficial effects on aging and aging-related conditions in humans./.../
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