Saturday, May 02, 2015

packaged bundles of cellular DNA

Scientists discover key driver of human aging
May 1, 2015

Salk Institute researchers discovered that a protein mutated in the premature aging disorder, Werner syndrome, plays a key role in stabilizing heterochromatin, a tightly packaged form of DNA. More generally, the findings suggest that heterochromatin disorganization may be a key driver of aging. This image shows normal human cells (left) and genetically modified cells developed by the Salk scientists to model Werner syndrome (right), which showed signs of aging, including their large size. (Credit: Salk Institute for Biological Studies) 
Salk Institute findings on premature aging syndrome could lead to way of slowing or reversing aging process
A study tying the aging process to the deterioration of tightly packaged bundles of cellular DNA could lead to methods of preventing and treating age-related diseases such as cancer, diabetes and Alzheimer’s disease, scientists at the Salk Institute and the Chinese Academy of Science note in a paper published Thursday, April 30 in the journal … more…
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