Parabiosis

“Young Blood” Anti-Aging Mechanism Called into Question

A protein in the blood of young mice that seemed to rejuvenate older animals may do the opposite

By Sara Reardon and Nature magazine | May 22, 2015

For decades, scientists have sought to understand the anti-ageing effects of parabiosis, a technique in which researchers sew a young mouse and an old mouse together so that they share a circulatory system. 

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The hunt for the fountain of youth is back to square one—at least for those seeking it in blood. New findings cast doubt on research that attempted to explain why the muscles of an old animal can be rejuvenated with a dose of blood from a young animal.