Sunday, June 14, 2015

human cortical spheroids

A 3-D human ‘organoid’ brain in a dish
June 12, 2015

Neurons and supporting cells in the spheroids form layers and organize themselves according to the architecture of the developing human brain and network with each other. (credit: Sergiu Pasca, M.D., Stanford University) 
Growing a miniature brain from cell scrapings could help diagnose brain disorders in a the future, Gattaca-style
Sergiu Pasca, M.D., of Stanford University and colleagues have developed “human cortical spheroids” — miniature cultured 3-D structures that grow and function much like the cortex of the brain of the person from whom they were derived. These “organoids” (3-D complexes of cells that function like an organ) buzz with neuronal network activity. Cells talk … more…

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