‘senolytic’ drugs

Clearing out the clutter: ‘senolytic’ drugs improve vascular health in mice

February 11, 2016

Reduced calcification of plaques on blood-vessel walls Mayo Clinic researchers have demonstrated the first study in which repeated treatments to remove senescent cells (cells that stop dividing due to age or stress) in mice improve age-related vascular conditions — and may possibly reduce cardiovascular disease and death. The researchers intermittently gave the mice a cocktail of two senolytic drugs (ones that selectively … more…