Falling asleep and waking up are key transitions in everyone’s day. Millions of people have trouble with these transitions – they find it hard to fall asleep or stay asleep at night, and hard to stay awake during the day. Despite decades of research, how these transitions work – the neurobiological mechanics of our circadian rhythm – has remained largely a mystery to brain scientists.
Now, however, scientists at the University of Maryland School of Medicine (UM SOM) have identified the workings of a key pathway for these processes. The pathway that appears to play a key role in regulating the “switch” between wakefulness and sleep. This is the first study to elucidate this process in such biophysical detail./.../
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