Fasting Turn Back the Clock?

June 28, 2017

Can a Diet That Mimics Fasting Turn Back the Clock?

Jennifer Abbasi

Article Information

JAMA. Published online June 28, 2017. doi:10.1001/jama.2017.6648

Adecade ago, researchers investigating the antiaging effects of caloric restriction in humans set an ambitious goal for their study participants: decrease daily calories by 25%. On average, the group of nonobese adults were only able to cut down by 12% over the 2-year investigation, despite receiving intensive dietary and behavioral counseling. Significant changes in the study’s primary end points—resting metabolic rate and core body temperature—didn’t materialize either. These 2 factors are believed to slow aging in animal models of caloric restriction. Does that mean the study failed? Not necessarily.

Even though the results weren’t comparable with those in animal models, a few bright spots emerged. The second phase of the Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE 2) trial, which was funded by the National Institute on Aging (NIA) and the National Institute of Diabetes and Digestive and Kidney Diseases, demonstrated that it’s feasible for humans to limit calories for an extended period. In addition, participants who cut back on calories lost weight and kept it off for the duration of the study. There were no adverse effects on quality of life and the participants netted improvements in blood pressure, cholesterol, and insulin resistance—all risk factors of age-related diseases.

Delivery time

Why Are so Many Babies Born around 8:00 A.M.?

Data visualization engineer Zan Armstrong takes a close look at human birth patterns.

• STAFFBy Zan Armstrong on June 20, 2017
•  4

Credit: Nadieh Bremer and Zan Armstrong; SOURCE: Centers for Disease Control and Prevention

Editor’s Note: The following is a guest post from data visualization engineer and data analyst Zan Armstrong.

As humans, our lives are filled with routines, habits and schedules. There are times that we wake up, go to school or work, or to the gym. We have routines around coffee breaks, rush hour traffic, meetings and soccer games.

Yet, there are some things that break our routines. Many families have a story of the baby that was born minutes after Dad’s heroic drive to the hospital, speeding across town in the middle of the night; or the sister or brother who almost died but for a last-minute C-section that saved their life; or the friend who labored for 27 painful hours before the little one finally came out./.../

Neural activity register

Researchers have developed a way to label neurons when they become active, essentially providing a snapshot of their activity at a moment in time. NeuroscienceNews.com image is credited to MIT. A Snapshot of Neural Activity by Neuroscience News

A new neuron labeling technique allows researchers to obtain a snapshot of their activity at any moment in time. The new approach could provide new insights into neural functioning by offering better precision than current, more long term, labeling techniques.

Read more of this post

Neuroscience News | June 27, 2017 at 10:40 am | Tags: FLARE | URL: http://wp.me/p4sXNK-aSn

Comment

See all comments

Mammography Screening

Women’s Awareness and Perceived Importance of the Harms and Benefits of Mammography Screening: Results From a 2016 National Survey   Jiani Yu, BA; Rebekah H. Nagler, PhD; Erika Franklin Fowler, PhD; et al	YOU ALSO MAY LIKE Breast Cancer Screening for Women at Average Risk-2015 Guideline Update From the American Cancer Society

To Fight Cancer

Joe and Jill Biden: We’re Changing How We Fight Cancer

Joe and Jill Biden

Jun 26, 2017

IDEAS

Joe Biden was the 47th Vice President of the United States; Dr. Jill Biden is a professor at Northern Virginia Community College and was Second Lady of the United States from 2009–2017; both are co-chairs of the Biden Cancer Initiative's board of directors.

Edward Gibbon (8/05/1737 - 16/01/1794)

Edward Gibbon

From E. Britannica

Edward Gibbon, (born May 8 [April 27, Old Style], 1737, Putney, Surrey, England—died January 16, 1794, London), English rationalist historian and scholar best known as the author of The History of the Decline and Fall of the Roman Empire (1776–88), a continuous narrative from the 2nd century ce to the fall of Constantinople in 1453.

Life

Gibbon’s grandfather, Edward, had made a considerable fortune and his father, also Edward, was able to live an easygoing life in society and Parliament. He married Judith, a daughter of James Porten, whose family had originated in Germany. Edward, too, had independent means throughout his life. He was the eldest and the only survivor of seven children, the rest dying in infancy./.../

Primary Health Care

Indicado pelo AMICOR Reginaldo Hollanda Albuquerque (Brasília)

New WHO advisory group launched in Almaty to shape the future of primary health care

20-06-2017

WHO

Minister of Health of Kazakhstan, Dr Yelzhan Birtanov, and WHO Regional Director for Europe, Dr Zsuzsanna Jakab.

Experts convened in Almaty, Kazakhstan, on 20–21 June 2017 for the inaugural meeting of the Primary Health Care Advisory Group. The WHO Regional Director for Europe launched the Advisory Group to advance primary health care in the WHO European Region.

At its first meeting, the Advisory Group engaged in discussions on the readiness and responsiveness of primary health care to embrace future health and social needs./.../

crowdsourcing médico

COMO VOCÊ PODE AJUDAR MÉDICOS DO OUTRO LADO DO PLANETA?

A SERMO tem um canal virtual para a rápida colaboração entre os médicos cruzando fronteiras para ajudar a resolver casos.Chamamos de crowdsourcing médico, um recurso ao qual você tem total acesso na SERMO. O crowdsourcing médico possibilita aos médicos em qualquer ponto do mundo postar casos reais e receber ajuda para resolvê-los, de centenas de outros colegas ao toque de um botão.

Um exemplo que mostra o poder do crowdsourcing médico da SERMO foi o caso de um garoto de 14 anos com uma tosse incômoda que acabou sendo algo muito mais sério...

SAIBA MAIS

Health Professions Social Mission

Viewpoint

June 26, 2017

Social Mission in Health Professions EducationBeyond Flexner

Fitzhugh Mullan, MD¹

Author Affiliations Article Information

JAMA. Published online June 26, 2017. doi:10.1001/jama.2017.7286

Education, research, and service are well-established missions of health professions schools and teaching hospitals in the United States. The role of social mission in these institutions is vitally important but less clear. Broadly defined, the social mission of a health professions school is the contribution of the school in its mission, programs, and the performance of its graduates, faculty, and leadership to enhancing health equity and to addressing the health disparities of the society in which it exists.¹ School characteristics that are associated with commitment to social mission, include community engagement, promotion of diversity, reduction in health disparities, the responsible use of health resources, and a focus on the social determinants of health.

Social mission is about making health not only better but fairer—more just, reliable, and universal. It focuses on the purpose of education in the health professions, the ethical dimension of what it is to be a teaching institution and to whom the institution is accountable. What will the graduates of the school, generalist or specialist, learn about the health disparities in their communities and their potential roles in reducing them? Will they gain an understanding of the challenges of diversity in the health professions? Will they be taught to respect and protect medical resources? Will these missions be modeled by their faculty? Will the education they receive prepare them to be practitioners and leaders in a transforming health care system./.../

Megacities and Borders

VIDEO SERIES  FAST FORWARD PredicTED: The Future of Borders In 50 years, what will your passport say? WATCH

Cesar Gomes Victora: AMICOR,Membro da Academia Sul-Riograndense de Medicina Candidato ao Nobel

Noticia slecionada pelo AMICOR Reginaldo Hollanda Albuquerque (Brasília)

Brasileiro com trabalho na área de Saúde Materno-infantil recebe prêmio no Canadá e entra na lista dos candidatos ao Nobel de Medicina

29/03/2017

Foto: arquivo pessoal

O professor emérito da Universidade Federal de Pelotas, dr Cesar Victora, 65 anos, se tornou nesta terça-feira (28) o primeiro brasileiro a receber o prêmio Gairdner de Saúde Pública, um dos mais importantes do mundo. O pesquisador na área da pediatra e epidemiologista teve o trabalho reconhecido pelo impacto na saúde materno-infantil e na nutrição de nações pobres e em desenvolvimento. Graças às pesquisas desenvolvidas por ele, na década de 1980, a Organização Mundial de Saúde (OMS) e o Fundo das Nações Unidas para a Infância (Unicef) reviram as recomendações sobre aleitamento exclusivo até os seis meses de vida. /.../

2821 - AMICOR 20

TED's Week

Aloyzio AchuttiemAMICOR - Há 12 horas

101 books to dive into this summer: a massive reading listA huge list of TED speaker-recommended books, with all the diversity of titles and topics you might expect — we’ve got you covered for every mood, preference and occasion. *Read more »*

WHO 10 years

Aloyzio AchuttiemAMICOR - Há 3 dias

WHO: Guardian of Health Health is essential for people to reach their full potential. That’s why WHO works to make sure everyone everywhere has access to health services wherever and whenever they need them. WHO has been serving its unique role as the guardian of health for seven decades.

Drynaria Rhizome

Aloyzio AchuttiemAMICOR - Há 4 dias

Plant Reveals Anti-Alzheimer’s Compoundsby Neuroscience News Researchers have identified several active compounds from Drynaria Rhizome that appear to be able to improve memory and reduce disease characteristics in mouse models of Alzheimer's disease. Read more of this post *Neuroscience News* | June 20, 2017 at 11:25 am | Tags: Drynaria Rhizome, Frontiers, naringenin, neurodegnerative diseases | URL: http://wp.me/p4sXNK-aPO Comment See all comments

DNA replication filmed

Aloyzio AchuttiemAMICOR - Há 4 dias

DNA Replication Has Been Filmed For The First Time, And It's Not What We Expected "It undermines a great deal of what's in the textbooks." DNA Replication Has Been Filmed For The First Time, And It's Not What We Expected "It undermines a great deal of what's in the textbooks." BEC CREW 19 JUN 2017 Here's proof of how far we've come in science - in a world-first, researchers have recorded up-close footage of a single DNA molecule replicating itself, and it's raising questions about how we assumed the process played out. The real-time footage has revealed that this fundamental part of l... mais »

Richest People

Aloyzio AchuttiemAMICOR - Há 5 dias

From Time.com The Richest People in the World Jennifer Calfas May 25, 2017 The richest people in the world have a staggering amount of wealth — comparable to the GDP of small countries for some. Many of the world's richest, like Microsoft founder Bill Gates or Facebook co-founder Mark Zuckerberg are self-made and took an idea that they turned into a billion-dollar fortune. For others, like the Koch brothers of Koch Industries, their businesses were inherited, but their control of the company led to overwhelming amounts of wealth.

Dementia

Aloyzio AchuttiemAMICOR - Há 5 dias

Dementia: a carer's insight [image: Opens large image]Christina Wayman Published: 16 May 2017 [image: Article has an altmetric score of 5]Summary - Full Text - Tables and Figures Many public awareness campaigns intend to improve society's understanding of dementia, its symptoms, and the difficulties faced by patients. Often less well described are the challenges faced by carers, be they family or professional caregivers. In *The Dementia Whisperer: scenes from the frontline of caring* by Agnes Juhasz, the reader gains insight into the life of an experienced live-in carer for a ... mais »

Santiago Ramón y Cajal and the Brain

Aloyzio AchuttiemAMICOR - Há 6 dias

Beautiful Brain: The Stunning Drawings of Neuroscience Founding Father Santiago Ramón y Cajal Oliver Sacks insisted that “ideas emerge, are shaped, in the act of writing,” which he considered “a special, indispensable form” of talking to himself. Unusual creature though he was, the beloved neurologist was not the only scientist who turned to other forms of creative expression as a clarifying force for scientific inquiry. The Spanish histologist, onetime bodybuilder, selfie pioneer, and Nobel laureate *Santiago Ramón y Cajal* (May 1, 1852–October 17, 1934), widely considered the found... mais »

Einstein: connection and justice

Aloyzio AchuttiemAMICOR - Há 6 dias

Einstein on the Interconnectedness of Our Fates and Our Mightiest Counterforce Against Injustice *“We must mend what has been torn apart, make justice imaginable again in a world so obviously unjust, give happiness a meaning once more,”* Albert Camus wrote in reflecting on strength of character in turbulent times as WWII’s maelstrom of deadly injustice engulfed Europe. But that mending is patient, steadfast, often unglamorous work — it is the work of choosing kindness over fear, again and again, in the smallest of everyday ways, those tiny triumphs of the human spirit which converge ... mais »