Wednesday, October 29, 2014

DM and sub-clinical Myocardial Damage

  • Original Article
    • Epidemiology and Prevention

Diabetes Mellitus, Prediabetes, and Incidence of Subclinical Myocardial Damage

  1. From the Department of Epidemiology and the Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (E.S., M.L., Y.C., L.S., J.W.M., A.R.S., J.C.); Division of General Internal Medicine, Department of Medicine, Johns Hopkins University, Baltimore, MD (E.S., M.L., J.R., J.C.); Department of Medicine, Baylor College of Medicine and Methodist DeBakey Heart and Vascular Center, Houston, TX (R.C.H., C.M.B.).
  1. Correspondence to Elizabeth Selvin, PhD, MPH, Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Bloomberg School of Public Health, 2024 E Monument St, Suite 2–600, Baltimore, MD 21287. E-maileselvin@jhu.edu

Abstract

Background—Persons with prediabetes and diabetes mellitus are at high risk for cardiovascular events. However, the relationships of prediabetes and diabetes mellitus to the development of subclinical myocardial damage are unclear.
Methods and Results—We measured cardiac troponin T with a highly sensitive assay (hs-cTnT) at 2 time points, 6 years apart, among 9051 participants of the community-based Atherosclerosis Risk in Communities Study with no diabetes mellitus, or prediabetes, and without cardiovascular disease including silent myocardial infarction by ECG. First, we examined the incidence of elevated hs-cTnT (≥14 ng/L) at 6 years of follow-up. Second, we examined clinical outcomes during the subsequent ≈14 years of follow-up among persons with and without incident elevations in hs-cTnT. Cumulative probabilities of elevated hs-cTnT at 6 years among persons with no diabetes mellitus, prediabetes, and diabetes mellitus were 3.7%, 6.4%, and 10.8%, respectively. Compared with normoglycemic persons, the adjusted relative risks for incident elevated hs-cTnT were 1.40 (95% CI, 1.08–1.80) for prediabetes and 2.47 (95% CI, 1.78–3.43) for diabetes mellitus. Persons with diabetes mellitus and incident elevations in hs-cTnT were at a substantially higher risk of heart failure (hazard ratio, 6.37 [95% CI, 4.27–9.51]), death (hazard ratio, 4.36 [95% CI, 3.14–6.07]), and coronary heart disease (hazard ratio, 3.84 [95% CI, 2.52–5.84]) compared with persons without diabetes mellitus and no incident elevation in hs-cTnT.
Conclusions—Prediabetes and diabetes mellitus were independently associated with the development of subclinical myocardial damage, as assessed by hs-cTnT, and those persons with evidence of subclinical damage were at highest risk for clinical events. These results support a possible deleterious effect of hyperglycemia on the myocardium, possibly reflecting a microvascular cause.

Cocoa and Memory


Small study suggests supplement may support memory in aging
New research found that a dietary intervention of flavanols extracted from cocoa beans may improve function in a region of the brain associated with memory. The small study (only 37 participants) showed that after three months of consuming a high-flavanol diet, participants with the typical memory of a 60-year-old improved their memory to that of a 40-year-old. Large-scale, long-term studies are needed before these findings can be generalized, and the researchers cautioned that the findings don’t mean the average person should consume more chocolate or cocoa to boost their memory. Almost all flavanols disappear when the beans are processed into chocolate. Flavanols are also in some teas, wine, fruits, vegetables and other plant species.

Click here to read more

Blau Souza

Social Media

Facebook Creams Expectations While Twitter’s User Growth Stumbles

SWEDEN-FACEBOOK-DATA-CENTER-SERVERS
This picture taken with a fisheye lens shows a man walks past a big logo created from pictures of Facebook users worldwide in the company's Data Center, its first outside the US on November 7, 2013 in Lulea, in Swedish Lapland.JONATHAN NACKSTRAND—AFP/Getty Images
mobile now seem like a distant memory, as mobile now makes up two-thirds of the company’s ad revenue. /.../

Cadeia alimentar

Wolves Change Rivers
lobos

Sunday, October 26, 2014

2677 - AMICOR 17

Eleições 2014

Influenza

Aloyzio AchuttiemAMICOR - Há 7 minutos
Influenza A/H1N1 - Influenza 3D model - Influenza A/H1N1 The most scientifically precise 3D model of the influenza virus ever created provides an exceptionally detailed image of one of the world’s most common and deadly viruses./.../

Endowed Progress Effect

Aloyzio AchuttiemAMICOR - Há 37 minutos
How To Force People To Do Anything (And Have Them Thank You For it) 103,430 39 [image: estheringlis-arkell] Esther Inglis-ArkellProfileFollow Esther Inglis-Arkell Filed to: PSYCHOLOGY - EVIL - THE ENDOWED PROGRESS EFFECT - SCIENCE Tuesday 8:00am [image: How To Force People To Do Anything (And Have Them Thank You For it)] Does someone in your life not want to do something? Do you not care, even the slightest bit, about their wishes? Here's how to force them to complete a task they don't care about, and even feel superior while you're doing it. *The Endowed Progress Effect/.../*

23 de outubro de 2014

Aloyzio AchuttiemAMICOR EXTENSION - Há 12 horas
*ANIVERSÁRIO DO ANTONIO ACHUTTI OLIVÉ* Reunimos quase toda a família, alguns amigos e cuidadoras Voltamos a reutilizar a churrasqueira no alpendre que fica nos fundos de nosso pátio. Foi muito bom. Abaixo uma foto com quase todos

Breast Cancer

Aloyzio AchuttiemAMICOR - Há 18 horas
Insights on breast cancer Breast cancer is the most common cancer among women worldwide. Listen as researchers, doctors, technologists -- and a dancer -- share their perspectives. Watch » 7 TED Talks • Total run time 1:56:53

Physical Activity Best Dose

Aloyzio AchuttiemAMICOR - Há 19 horas
- Editorial Physical Activity and Health: What Is the Best Dose? 1. Leonard A. Kaminsky, PhD; 2. Alexander H. K. Montoye, PhD +Author Affiliations 1. 1Clinical Exercise Physiology Program, Human Performance Laboratory, Ball State University, Muncie, IN (L.A.K., A.K.M.) 1. Correspondence to: Leonard A. Kaminsky, PhD, Clinical Exercise Physiology Program, Human Performance Laboratory, Ball State University, Muncie, IN 47306. E‐mail: kaminskyla@bsu.edu Key Words: - Editorials - exercise - health outcomes - lifestyle - morbidity/morta... mais »

INBOX

Aloyzio AchuttiemAMICOR - Há 21 horas
[image: Bits - Business, Innovation, Technology, Society]STATE OF THE ART Google Wants Inbox to Be Your Email System for the Next Decade By FARHAD MANJOO OCTOBER 22, 2014 1:00 PMOctober 22, 2014 1:00 pm A promotional video for Inbox. Google’s signature email program first hit the Web in 2004. In its earliest days, it was a godsend to everyone who battled against a daily rush of messages.Two years ago, a team of engineers and designers on Google’s Gmail team decided that Gmail wasn’t cutting it.

Harassement Online

Aloyzio AchuttiemAMICOR - Há um dia
40 Percent of US Adults Harassed Online The conversation about bullying often revolves around youngsters, but they are not the only victims. Data show that some 40 percent of US adults face harassment online in the form of name-calling, intentional embarrassment, threats, sexual harassment, and stalking. Of adults targeted in this manner, young adults are the most frequently victimized, with 65 percent reporting being subjected to such harassment. Gender also appears to influence the type of online harassment one faces, with men more likely to experience name-calling and women more l... mais »

Mental illness and society

Aloyzio AchuttiemAMICOR - Há um dia
A better response to Ottawa shooting "Too often those with mental illness and those who suffer from terrible addictions are ignored and left to their own devices in a society that has not provided the necessary care," said Prime Minister Stephen Harper in the House of Commons. - See more at: http://www.ffwdweekly.com/calgaryblogs/politics/a-better-reponse-to-ottawa-shooting/#sthash.XG4ASv50.XGtiEE9s.dpuf/.../

Personal x Digital Spaces

Aloyzio AchuttiemAMICOR - Há um dia
Ask Ray | US Supreme Court acknowledges that personal space has merged with the digital worldJune 28, 2014 by Ray Kurzweil *[+]*[image: (credit: iStock)] Dear readers, My friend — of 50 years! — Mark Bergmann, brought this recent quote from US Supreme Court Chief Justice John Roberts to my attention: “Modern cell phones are such a pervasive and insistent part of daily life that the proverbial visitor from Mars might conclude they were an important feature of human anatomy,” said Roberts, commenting in the recent Supreme Court ruling on cell phones warrants.… read more *Topics:* Interne... mais »

Humanity Future

Aloyzio AchuttiemAMICOR - Há um dia
Wild ride ahead: glimpse at humanity’s long range futureJuly 23, 2014 by Richard (Dick) Pelletier *[+]*[image: A Type III civilization can harness all the energy of a galaxy (credit: ESA)] Imagine if you could take an exotic vacation billions of light years from Earth, peek in on the dinosaurs’ first-hand, or jump into a parallel universe where another you is living a more exciting life than yours — and you could swap places if you like. For years, scientists have bandied about radical ideas that future humans will one day harness wormholes to zip across the universe at faster-than-l... mais »

signatures’ of consciousnes

Aloyzio AchuttiemAMICOR - Há um dia
‘Hidden brain signatures’ of consciousness in vegetative state patients discoveredOctober 21, 2014 *[+]*[image: Brain networks in two behaviourally-similar vegetative patients (left and middle), but one of whom imagined playing tennis (middle panel), alongside a healthy adult (right panel) (Credit: Srivas Chennu)] Scientists in Cambridge, England have found hidden signatures in the brains of people in a vegetative state that point to networks that could support consciousness — even when a patient appears to be unconscious and unresponsive. The study could help doctors identify patient... mais »

Universe timeline

Aloyzio AchuttiemAMICOR - Há um dia
The incredible unlikelihood of beingJuly 24, 2014 http://www.kurzweilai.net/ask-ray-the-incredible-unlikelihood-of-being *[+]*[image: (credit: iStock)] Hello Ray, The universe existed several billion years before humans were conscious, and will exist several billion years after we are conscious. So, it is statistically improbable for the chronological timeline of the universe to be located at this precise moment, when we are conscious, that is, an 80 year lifespan within some 30 billion years. Are you aware of any theories, besides survivorship bias from statistics, that… read more *To... mais »

Being Mortal

Aloyzio AchuttiemAMICOR - Há um dia
Managing mortality Euan Ashley a[image: Email Address] Being Mortal: Medicine and What Matters in the End Atul Gawande Metropolitan Books/Henry Holt and Company, 2014304 US$26·00 ISBN-9780805095159 Ignoring W C Fields' famous advice never to work with children or animals, Dr Bill Thomas introduced both to the Chase Memorial Nursing Home in New York during the 1980s: two dogs, four cats, 100 parakeets, a colony of rabbits, a flock of chickens, and an on-site childcare facility for staff, to be precise. The initial effect was chaos (especially since the birds arrived uncaged), but over t... mais »

All-Purpose Antidepressants

Aloyzio AchuttiemAMICOR - Há 3 dias
Mind & Brain » Scientific American Mind Volume 25, Issue 6 » Head Lines - 1 - Email - Print See Inside[image: Scientific American Mind Volume 25, Issue 6]The Rise of All-Purpose Antidepressants Doctors are increasingly prescribing SSRIs to treat more than just depression Oct 16, 2014 |By Julia Calderone Antidepressant use among Americans is skyrocketing. Adults in the U.S. consumed four times more antidepressants in the late 2000s than they did in the early 1990s. As the third most frequently taken medication in the U.S., researchers estimate that 8 to 10 percent of the p... mais »

Population Digital Visualization - Infographics

Aloyzio AchuttiemAMICOR - Há 4 dias
[image: prb_webupdate_header] Oct. 21, 2014 [image: url] [image: facebook] [image: twitter] [image: youtube] [image: soundcloud] [image: world-population-dataviz-circles] *World Population Digital Visualization* PRB's award-winning Digital Visualizationhighlights key global demographic trends. Explore current and projected population by region and country. And look at changes in total fertility, infant mortality, and life expectancy since 1970. A U.S. "What-If" scenario focuses on the effects of race and ethnicity on child poverty, child obesity, and college degrees. See more... mais »

Breast Cancer

Aloyzio AchuttiemAMICOR - Há 4 dias
Genetic Variant May Shield Latinas From Breast Cancer By ANAHAD O'CONNOR OCTOBER 20, 2014 11:20 PMOctober 20, 2014 11:20 pm Comment Photo CreditStuart Bradford A genetic variant that is particularly common in some Hispanic women with indigenous American ancestry appears to drastically lower the risk of breast cancer, a new study found. About one in five Latinas in the United States carry one copy of the variant, and roughly 1 percent carry two./.../

Influenza

The most scientifically precise 3D model of the influenza virus ever created provides an exceptionally detailed image of one of the world’s most common and deadly viruses./.../

Endowed Progress Effect

How To Force People To Do Anything (And Have Them Thank You For it)

How To Force People To Do Anything (And Have Them Thank You For it)
Does someone in your life not want to do something? Do you not care, even the slightest bit, about their wishes? Here's how to force them to complete a task they don't care about, and even feel superior while you're doing it.
The Endowed Progress Effect/.../

Saturday, October 25, 2014

Breast Cancer

Insights on breast cancer

Breast cancer is the most common cancer among women worldwide. Listen as researchers, doctors, technologists -- and a dancer -- share their perspectives. Watch »
7 TED Talks • Total run time 1:56:53