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Saturday, August 17, 2019

2935 - AMICOR 22

Office x Ambulatory BP

Aloyzio AchuttiemAMICOR - Há 27 minutos
August 6, 2019 Association of Office and Ambulatory Blood Pressure With Mortality and Cardiovascular Outcomes Wen-Yi Yang, MD, PhD1,2; Jesus D. Melgarejo, MD3; Lutgarde Thijs, MSc1; et alZhen-Yu Zhang, MD, PhD1,2; José Boggia, MD, PhD4; Fang-Fei Wei, MD, PhD1; Tine W. Hansen, MD, PhD5; Kei Asayama, MD, PhD6,7; Takayoshi Ohkubo, MD, PhD6,7; Jørgen Jeppesen, MD, PhD8; Eamon Dolan, MD, PhD9; Katarzyna Stolarz-Skrzypek, MD, PhD10; Sofia Malyutina, MD, PhD11; Edoardo Casiglia, MD, PhD12; Lars Lind, MD, PhD13; Jan Filipovský, MD, PhD14; Gladys E. Maestre, MD, PhD3,15; Yan Li, MD, PhD16; Ji-... mais »

39 Ancient Galaxies

Aloyzio AchuttiemAMICOR - Há 29 minutos
Astronomers Uncover 39 Ancient Galaxies — Moving So Fast That Even Hubble Can't See Them By Rafi Letzter 4 days ago Space These galaxies could rewrite our history of the early universe.[image: Part of ALMA is pictured] Part of the Atacama Large Millimeter/submillimeter Array (ALMA) is pictured. (Image: © Image (c) 2019 Kohno et al.) Ancint, massive galaxies haunting the dusty reaches of our universe have been in hiding, invisible to the eyes of the famous Hubble Space Telescope. But now, astronomers sifting through infrared data have discovered 39 of them — lurking in strange places ... mais »

Cultura indígena

Aloyzio AchuttiemAMICOR - Há 31 minutos
*Link*

AD Genetics

Aloyzio AchuttiemAMICOR - Há 2 dias
Gene Study Yields Possible New Alzheimer's Target by Judy George, Senior Staff Writer, MedPage Today August 14, 2019 [image: Human macrophages stained with TREM2 (red) and MS4A4A (green). [Credit: Fabia Filipello and Dennis Oakley]] A mechanistic explanation of how two genes may influence Alzheimer's disease risk has been identified, researchers reported. The genes, known as *MS4A4* (membrane-spanning 4-domains subfamily A) and *TREM2* (triggering receptor expressed on myeloid cells 2), operate in the microglia and appeared to influence Alzheimer's risk by altering levels of TREM2, a ... mais »

2019 ACC/AHA Guideline: Primary Prevention CVD:

Aloyzio AchuttiemAMICOR - Há 3 dias
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Part 1, Lifestyle and Behavioral Factors Donna K. Arnett, PhD, MSPH1; Amit Khera, MD, MSc2; Roger S. Blumenthal, MD3 Author Affiliations Article Information JAMA Cardiol. Published online July 31, 2019. doi:10.1001/jamacardio.2019.2604 *Guideline title:* 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease *Developers:* American College of Cardiology and American Heart Association *Release date:* March 17, 2019 (online) *Funding sources:* American College of Cardiology and American Heart A... mais »

Evil

Aloyzio AchuttiemAMICOR - Há 3 dias
[image: ScienceWebinars | AAAs] FREE WEBINAR September 04 2019 12:00 PM to 1:00 PM US Eastern Time Impulses, intent, and the science of evil Register now! During the webinar, we will discuss: How we might define "evil" and whether there are evil people or just evil acts Whether studying evil can broaden our understanding of the causes and triggers of violence The link between mental illness and "evil" acts. Speakers [image: head shot of Abigail Marsh, Ph.D.] Abigail Marsh, Ph.D. Georgetown University Washington, DC [image: head shot of Michael Stone, M.D.] Michael Stone, M.D. Columbi... mais »

Alzheimer's Disease

Aloyzio AchuttiemAMICOR - Há 3 dias
Anxiety an additional challenge for those facing Alzheimer's Approximately 80 percent of people living with dementia will experience agitation and anxiety. Identifying triggers, such as a change in schedule or physical discomfort, can be helpful for caregivers. Playing the person's favorite music or using other techniques to shift their attention can also help. [image: Click here to read more] Almost two-thirds of Americans with Alzheimer's are women Researchers are investigating why Alzheimer's disease affects more women than men, and why it progresses more quickly in women's bra... mais »

Falando em Previdência...

Aloyzio AchuttiemAMICOR - Há 3 dias
[image: U.S. Social Security card.] 1935: The U.S. Congress enacted the Social Security Act , establishing a permanent national old-age pension system through employer and employee contributions.

Cicadas

Aloyzio AchuttiemAMICOR - Há 3 dias
[image: How Much Trash Is in Space] *DEMYSTIFIED* Why Are Cicadas So Noisy? Who doesn't love bugs? Well, OK, maybe not everyone loves bugs. However, whether we like it or not, with the warm months come an influx of insects, including the cicada. And with the cicada comes the noise. That far-reaching, sometimes overwhelming buzz is ubiquitous with the summer months and can leave you wondering: "How in the world are these little bugs so loud?" Check out this week's *Demystified *to learn more about cicadas, how they produce that sound, and why! Learn More

Dia do Cardiologista

Aloyzio AchuttiemAMICOR - Há 3 dias
*Dia do Cardiologista* A Sociedade Brasileira de Cardiologia comemora 76 anos. A data de sua fundação, 14 de agosto, é também um momento para celebrar o Dia do Cardiologista. Uma história de longevidade e, ao mesmo tempo, dinamismo e modernidade. Fundada por Dante Pazzanese, em 1943, a SBC foi a 5ª sociedade nacional no continente americano e a 13ª no mundo e se mantém forte e pujante. Atualmente é a 3ª maior sociedade nacional da especialidade, somente atrás do *American College of Cardiology* e da *American Heart Association*. A SBC tem cerca de 14 mil sócios, regionais em todos ... mais »

CFM - Tabagismo Forum

Aloyzio AchuttiemAMICOR - Há 4 dias
Você recebeu este e-mail porque faz parte da lista do Conselho Federal de Medicina. *Se quiser ser removido acesse este link.*

Pregnant and migrant women

Aloyzio AchuttiemAMICOR - Há 4 dias
Prevalence and Odds of Common Mental Disorders Associated With Insecure Immigration Status Amond Migran Women Migrant Women and Antenatal Mental Health Fraser M. Anderson, Stephani L. Hatch, Elizabeth G. Ryan, Kylee Trevillion, and Louise M. Howard How do immigration status and ethnicity affect antenatal mental health among migrant women? Read this article to learn the prevalence and odds of common mental disorders in migrant women in the United Kingdom.

Fall of the Aztec empire

Aloyzio AchuttiemAMICOR - Há 4 dias
[image: Hernán Cortés (left) meeting Montezuma II, undated illustration.]FEATURED EVENT1521 READ MORE
Aloyzio AchuttiemAMICOR - Há 5 dias
SYMPOSIUM JCP ELERT/08.12.19 New Blog: Tobacco Smoking and Psychotic-Like Experiences: Are They Linked? Jasmina Mallet, Caroline Dubertret, and Yann Le Strat Related article:Tobacco Smoking and Psychotic-Like Experiences in a General Population Sample Jasmina Mallet, Nicolas Mazer, Caroline Dubertret, and Yann Le Strat Tobacco has known associations with psychosis, but less is known about the relationship between tobacco use and subclinical psychotic-like experiences (PLEs). This study sought to disentangle the association of tobacco with PLEs in a large nationally representative sample... mais »

Irisina

Aloyzio AchuttiemAMICOR - Há 5 dias
Hormônio do exercício pode evitar a perda de memória Ricardo Zorzetto ------------------------------ 14:00 7 jan 2019 Liberada pelos músculos, a irisina melhora o funcionamento dos neurônios e reduz o esquecimento em roedores com enfermidade semelhante ao Alzheimer Neste neurônio, os pontos de conexão (sinapses, *marcadas em verde*) com outras células foram restaurados pela ação da irisina, hormônio liberado pelos músculos durante o exercício físicoGuilherme Braga e Mychael Lourenço / UFRJ Fazer exercícios físicos regularmente melhora o desempenho da memória e parece retardar a ocorr...mais »

Jacobina Mentz Maurer

Aloyzio AchuttiemAMICOR - Há 5 dias

1887 - Erwin Schrödinger

Aloyzio AchuttiemAMICOR - Há 5 dias
[image: Schrödinger, Erwin] 1887: Austrian theoretical physicist Erwin Schrödinger, who shared the 1933 Nobel Prize for Physics for his contributions to the wave theory of matter and to other fundamentals of quantum mechanics , was born in Vienna.

1961 - Berlin Wall

Aloyzio AchuttiemAMICOR - Há 5 dias
[image: People from East and West Berlin gathering at the Berlin Wall on November 10, 1989, one day after the wall opened.] 1961: East Germany began construction of the Berlin Wall, which served as a symbol of the Cold War, separating East Berlin from West Berlin until 1989. Quando caiu o muro nosso filho Luiz Eduardo estava lá e fotografou

William Blake

Aloyzio AchuttiemAMICOR - Há 5 dias
[image: William Blake, oil on canvas by Thomas Phillips, 1807; in the National Portrait Gallery, London.]FEATURED BIOGRAPHY1757William Blake READ MORE

Office x Ambulatory BP

Key Points
Question  What is the association of office and ambulatory blood pressure with subsequent risk of mortality and cardiovascular outcomes?
Findings  In a population-based cohort of 11 135 adults, higher 24-hour and nighttime blood pressure readings were significantly associated with greater risks of death and cardiovascular events that included cardiovascular mortality combined with nonfatal coronary events, heart failure, or stroke. This association persisted after adjusting for other blood pressure measurements taken during an office visit or during ambulatory monitoring.
Meaning  Higher 24-hour and nighttime blood pressure readings were significantly associated with greater risks of death and a composite of cardiovascular outcomes, although statistically the incremental model improvement was small.

Abstract
Importance  Blood pressure (BP) is a known risk factor for overall mortality and cardiovascular (CV)-specific fatal and nonfatal outcomes. It is uncertain which BP index is most strongly associated with these outcomes.
Objective  To evaluate the association of BP indexes with death and a composite CV event.
Design, Setting, and Participants  Longitudinal population-based cohort study of 11 135 adults from Europe, Asia, and South America with baseline observations collected from May 1988 to May 2010 (last follow-ups, August 2006-October 2016).
Exposures  Blood pressure measured by an observer or an automated office machine; measured for 24 hours, during the day or the night; and the dipping ratio (nighttime divided by daytime readings).
Main Outcomes and Measures  Multivariable-adjusted hazard ratios (HRs) expressed the risk of death or a CV event associated with BP increments of 20/10 mm Hg. Cardiovascular events included CV mortality combined with nonfatal coronary events, heart failure, and stroke. Improvement in model performance was assessed by the change in the area under the curve (AUC).
Results  Among 11 135 participants (median age, 54.7 years, 49.3% women), 2836 participants died (18.5 per 1000 person-years) and 2049 (13.4 per 1000 person-years) experienced a CV event over a median of 13.8 years of follow-up. Both end points were significantly associated with all single systolic BP indexes (P < .001). For nighttime systolic BP level, the HR for total mortality was 1.23 (95% CI, 1.17-1.28) and for CV events, 1.36 (95% CI, 1.30-1.43). For the 24-hour systolic BP level, the HR for total mortality was 1.22 (95% CI, 1.16-1.28) and for CV events, 1.45 (95% CI, 1.37-1.54). With adjustment for any of the other systolic BP indexes, the associations of nighttime and 24-hour systolic BP with the primary outcomes remained statistically significant (HRs ranging from 1.17 [95% CI, 1.10-1.25] to 1.87 [95% CI, 1.62-2.16]). Base models that included single systolic BP indexes yielded an AUC of 0.83 for mortality and 0.84 for the CV outcomes. Adding 24-hour or nighttime systolic BP to base models that included other BP indexes resulted in incremental improvements in the AUC of 0.0013 to 0.0027 for mortality and 0.0031 to 0.0075 for the composite CV outcome. Adding any systolic BP index to models already including nighttime or 24-hour systolic BP did not significantly improve model performance. These findings were consistent for diastolic BP.
Conclusions and Relevance  In this population-based cohort study, higher 24-hour and nighttime blood pressure measurements were significantly associated with greater risks of death and a composite CV outcome, even after adjusting for other office-based or ambulatory blood pressure measurements. Thus, 24-hour and nighttime blood pressure may be considered optimal measurements for estimating CV risk, although statistically, model improvement compared with other blood pressure indexes was small.