Saturday, August 23, 2014

Colégio João XXIII: 50 anos.

Instituto Educacional - Colégio João XXIII

Comemoramos nesta semana 50 anos de sua fundação, pelas Zilah, Lamachia, Lilia e Leda.
Nossos três filhos lá estudaram e completaram a formação do ciclo secundário (Luiz Eduardo, Ana Lúcia e Lúcia Helena). Dois netos nossos lá estudam hoje Pedro Martin e Antônio Achutti Olivé.
Foi uma boa experiência de meio século atrás, participar das direções do Conselho de Pais e da Fundação que criamos para dar suporte à iniciativa dos quatro fundadores.

João dá show no São Pedro

O espetáculo '50 anos essa noite', no Theatro São Pedro, foi um show multimídia. Esquetes teatrais, apresentações musicais e vídeos com depoimentos de representantes da comunidade escolar fizeram parte do…

Friday, August 22, 2014

Datura inoxia
Follow Erowid
Nicotiana spp.
Hot Chiles
Bottle of 5-MeO-DMTCyclobenzaprine

passion flower
A peregrina seeds
ecstasy tablets
LSD Blotter

Social determinants of mental health

Social determinants of mental health

International Review of Psychiatry (Impact Factor: 1.8). 08/2014; 26(4). DOI: 10.3109/09540261.2014.928270
ABSTRACT A person's mental health and many common mental disorders are shaped by various social, economic, and physical environments operating at different stages of life. Risk factors for many common mental disorders are heavily associated with social inequalities, whereby the greater the inequality the higher the inequality in risk. The poor and disadvantaged suffer disproportionately, but those in the middle of the social gradient are also affected. It is of major importance that action is taken to improve the conditions of everyday life, beginning before birth and progressing into early childhood, older childhood and adolescence, during family building and working ages, and through to older age. Action throughout these life stages would provide opportunities for both improving population mental health, and for reducing risk of those mental disorders that are associated with social inequalities. As mental disorders are fundamentally linked to a number of other physical health conditions, these actions would also reduce inequalities in physical health and improve health overall. Action needs to be universal: across the whole of society and proportionate to need. Policy-making at all levels of governance and across sectors can make a positive difference.

Thursday, August 21, 2014

Breast Cancer

Vol. 345 no. 6199 pp. 865-867 
DOI: 10.1126/science.345.6199.865

The cancer drug that almost wasn't

A cancer drug discovered in 2001 that targets the cell cycle has recently shown promising efficacy in metastatic breast cancer. Pfizer's palbociclib, added to standard therapy, doubles the time women live with no new tumor growth. The drug, which inhibits a cell cycle protein called CDK4, has erased the legacy of failure of other cell cycle cancer therapies, and competitors have introduced their own versions, which show promise in multiple tumor types. But the drug could have emerged much sooner, say palbociclib's inventors, had Pfizer used a more sophisticated development strategy and not shelved the drug for much of the last decade. Pfizer disagrees, but it was only after outside investigators demonstrated palbociclib's potential in breast cancer that the company moved the drug forward.
  • * Ken Garber is a writer in Ann Arbor, Michigan.

Tuesday, August 19, 2014

abdominal obesity and migraine

Enviado pelo AMICOR Victor Matsudo

Obesity, abdominal obesity and migraine: A cross-sectional analysis of ELSA-Brasil baseline data.

Cephalalgia : an international journal of headache 08/2014;  DOI: 10.1177/0333102414544978
Source: PubMed Itamar S SantosAlessandra C Goulart,, Valeria M Passos,  Maria Del Carmen MolinaPaulo A Lotufo, Isabela M Bensenor
ABSTRACT Background and aim: Most studies assessing the association between migraine and obesity have shown conflicting results. We aimed to evaluate the association between obesity and migraine in ELSA-Brasil, a cohort study of 15,105 individuals aged 35-74 years. Methods: We assessed migraine using a validated questionnaire based on International Headache Society criteria and anthropometric measurements using standard techniques. Migraine was categorized as daily and non-daily. World Health Organization criteria were used to categorize overweight, obesity and abdominal obesity (AbO). We performed a cross-sectional analysis using multivariate logistic regression models to study the association between migraine and obesity (body mass index (BMI) ≥ 30 kg/m(2)), compared to controls without migraine. Results: We found an association between daily migraine and obesity (odds ratio (OR) 1.86; 95% confidence interval (95% CI): 1.12-3.09). Although the presence of AbO was not associated with migraine, interaction models showed that the association between obesity and daily migraine remained strong only in the absence of AbO diagnosis, notably in individuals aged 35-49 years. Discussion: In our large sample of individuals aged 35 years or older, obesity, but not AbO, was associated with daily migraine. AbO influenced the association between BMI and daily migraine in migraineurs aged 35-49 years.

Monday, August 18, 2014

Big Data's Bottleneck

Information Wrangling Is Big Data's Bottleneck | Technology revolutions come in measured, sometimes foot-dragging steps. The lab science and marketing enthusiasm tend to underestimate the bottlenecks to progress that must be overcome with hard work and practical engineering, Steve Lohr reports.
The field known as "big data" offers a contemporary case study. The catchphrase stands for the modern abundance of digital data from many sources - the web, sensors, smartphones and corporate databases - that can be mined with clever software for discoveries and insights. Its promise is smarter, data-driven decision making in every field. That is why data scientist is the economy's hot new job.
Yet far too much handcrafted work - what data scientists call "data wrangling," "data munging" and "data janitor work" - is still required. Data scientists, according to interviews and expert estimates, spend 50 to 80 percent of their time mired in this more mundane labor of collecting and preparing unruly digital data, before it can be explored for useful nuggets.
"Data wrangling is a huge - and surprisingly so - part of the job," said Monica Rogati, vice president for data science at Jawbone, whose sensor-filled wristband and software track activity, sleep and food consumption, and suggest dietary and health tips based on the numbers. "It's something that is not appreciated by data civilians. At times, it feels like everything we do."Read more »/.../

Saturday, August 16, 2014

2667 - AMICOR 17

Global Health

Aloyzio AchuttiemAMICOR - Há uma hora
*Por recomendação de Cristianne Famer Rocha* *6th Annual Global Health Conference* Mobilizing Research for Global Health Sheraton Boston Hotel | Boston, MA March 26-28, 2015 *CALL FOR ABSTRACTS* *and* *SAVE THE DATE*

About Risk and Personality

Aloyzio AchuttiemAMICOR - Há 12 horas
What Children Can Teach Us About Risk, Failure, and Personal Growth*by Maria Popova* *“Our fear of failure … assures the progressive narrowing of the personality.”* *“If I limit myself to knowledge that I consider true beyond doubt,”* E.F. Schumacher wrote in his timelessly wonderful *A Guide for the Perplexed* in 1977, *“I minimize the risk of error but I maximize, at the same time, the risk of missing out on what may be the subtlest, most important and most rewarding things in life.”* In the decades since, the notion of embracing risk and failure has become one of the most common t... mais »


Aloyzio AchuttiemAMICOR - Há um dia
Blood-brain-barrier disruption with high-frequency pulsed electric fields August 14, 2014 [image: A cortical microvessel stained for blood–brain barrier protein ZO-1 (credit: Nathan S. Ivey/Wikimedia Commons/)] A team of researchers from Virginia Tech and Wake Forest University School of Biomedical Engineering and Sciences have developed a new technique for using pulsed electric energy to open the blood-brain-barrier (BBB) for treating brain cancer and neurological disorders. Their Vascular Enabled Integrated Nanosecond pulse (VEIN pulse) procedure consists of inserting minimally inva... mais »

Black Hole

Aloyzio AchuttiemAMICOR - Há um dia
- [image: The Black Hole That Birthed the Big Bang]The Black Hole at the Beginning of TimeIs the big bang, and all that came from it, a holographic mirage from another dimension? Niayesh Afshordi, Robert B. Mann and Razieh Pourhasan|August 1, 2014| 32 PLUS: All You Need to Know about Gravitational Waves

The Most Distant Star

Aloyzio AchuttiemAMICOR - Há um dia
[image: stars at the edge of the galaxy]Far Out: The Most Distant Star in the Milky Way A star 890,000 light-years away patrols our galactic frontier Aug 11, 2014 |By Ken Croswell *FAINT AND FAR: *Lying 890,000 light-years from Earth, the ruddy star at center is the most distant object ever seen in our galaxy. *Credit: Sloan Digital Sky Survey* Just as every planet in the solar system orbits the sun, so every star in the Milky Way orbits the big black hole at our galaxy's center. But how far out does the Milky Way extend? Astronomers are closer to answering that question with the d... mais »

Strongest Muscle

Aloyzio AchuttiemAMICOR - Há um dia
Fact or Fiction?: The Tongue Is the Strongest Muscle in the Body Is this agile appendage as brawny as people believe? Aug 15, 2014 |By Julia Calderone and Ben Fogelson [image: little girl with tongue sticking out] *Credit: Johan Larsson via Flickr* It can bend, it can twist, it can suck, it can cup. The tongue is an essential, often playful part of human anatomy. Many of us grew up believing the assertion that the tongue is the strongest muscle in the body. But is it really? The short answer is no. But the explanation is not as straightforward as you’d think. We asked a few tongue e... mais »

Jeremiah Stamler Celebration

Aloyzio AchuttiemAMICOR - Há um dia
Father of the Preventive Cardiology

Gray's Anatomy

Aloyzio AchuttiemAMICOR - Há um dia
Henry Gray's *Anatomy of the Human Body*, commonly known as *Gray's Anatomy*, is widely regarded as a classic medical reference book. Due to the Anatomy Act of 1832, Henry Gray—an anatomist and teacher in London—was able to dissect unclaimed corpses from workhouses and form the basis of his book. First published under the title *Anatomy: Descriptive and Surgical* in 1858, his text has been expanded and reprinted numerous times. What disease claimed Gray's life when he was only 34? More... mais »


Aloyzio AchuttiemAMICOR - Há 2 dias
*A Hipótese que David Barker levantou tem dimensões bem maiores e mais profundas do que simplesmente as do domínio biológico (em sentido estrito). * [image: This week's cover]SPECIAL ISSUE | 15 AUGUST 2014Parenting - Table of Contents - About the Cover - More Special Issues INTRODUCTION—*Science*'s special section on parenting addresses how parents of any species pass on their DNA, but the biology of parenting and its impacts on the offspring don’t end at birth. Animal parenting behaviors, molecular legacy, and gestation and birthing processes are all highlighted in this i... mais »

More Exercise?

Aloyzio AchuttiemAMICOR - Há 3 dias
More Exercise Isn't Always Better A new report published in *Mayo Clinic Proceedings* finds there may be an upper limit to how helpful exercise can be on your heart

Dosagem de Vitamina D3

Aloyzio AchuttiemAMICOR - Há 4 dias
Journal of the American Board of Family Medicine A Predictive Equation to Guide Vitamin D Replacement Dose in Patients Gurmukh Singh, MD, PhD, MBA, Aaron J. Bonham, MS Disclosures J Am Board Fam Med. 2014;27(4):495-509.

WB: Inequality

Aloyzio AchuttiemAMICOR - Há 6 dias [image: Video: The Data Minute: What is Inequality of Opportunity?] VIDEO The Data Minute: What Is Inequality of Opportunity?

Global Health

Por recomendação de Cristianne Famer Rocha

6th Annual Global Health Conference
Mobilizing Research for Global Health
Sheraton Boston Hotel | Boston, MA
March 26-28, 2015

About Risk and Personality

What Children Can Teach Us About Risk, Failure, and Personal Growth

“Our fear of failure … assures the progressive narrowing of the personality.”
“If I limit myself to knowledge that I consider true beyond doubt,” E.F. Schumacher wrote in his timelessly wonderful A Guide for the Perplexed in 1977, “I minimize the risk of error but I maximize, at the same time, the risk of missing out on what may be the subtlest, most important and most rewarding things in life.” In the decades since, the notion of embracing risk and failure has become one of the most common tropes in motivational talks, self-help books and business articles alike. It’s been championed by everyone from Ray Bradbury, who considered failure essential to creativity, to Pixar co-founder Ed Catmull, who argued for the importance of cultivating a failure-fearless culture, but none more eloquently than social science writer John W. Gardner in a section of Self-Renewal: The Individual and the Innovative Society(public library) — his altogether fantastic, forgotten field guide to keeping your company and your soul vibrantly alive, which remains a must-read as much for entrepreneurs as for those of us on a private journey of self-transcendence./.../