Scientists Solve a Dengue Mystery: Why Second Infection Is Worse than First
Antibodies from a first bout can raise the risk of more severe disease if the virus is contracted later
For decades there has been a counterintuitive and hotly debated theory about dengue infections: that antibodies generated by a previous bout of dengue could actually put a person at risk of more severe disease if they contracted the virus a second time.
And now American and Nicaraguan scientists have published evidence that may silence the skeptics. Antibody-dependent enhancement, or ADE as it’s known in scientific circles, can happen, they reported, when subsequent infection occurs at a time when antibodies generated by the prior infection have fallen to a specific low range./.../
No comments:
Post a Comment