Melanoma

Association of Hydrochlorothiazide Use With Risk of Malignant Melanoma

Anton Pottegård, MScPharm, PhD¹; Sidsel Arnspang Pedersen, MD^1,2,3; Sigrun Alba Johannesdottir Schmidt, MD, PhD⁴; et alLisbet Rosenkrantz Hölmich, MD, DMSc⁵; Søren Friis, MD^4,6,7; David Gaist, MD, PhD^2,3

Author Affiliations Article Information

JAMA Intern Med. Published online May 29, 2018. doi:10.1001/jamainternmed.2018.1652

We have recently shown that hydrochlorothiazide use increases the risk of lip and nonmelanoma skin cancer, notably squamous cell carcinoma.^1,2 It would have substantial implications if the carcinogenic effect of hydrochlorothiazide also extended to malignant melanoma./...,/