Ablation x Clnical treatment

Effect of Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding, and Cardiac Arrest Among Patients With Atrial FibrillationThe CABANA Randomized Clinical Trial

Educational Objective
To learn whether catheter ablation is superior to conventional medical therapy for patients with atrial fibrillation (AF).

Related

1. Catheter Ablation for Atrial Fibrillation

2. Effect of Catheter Ablation vs Medical Therapy on Quality of Life in Patients With Atrial Fibrillation

3. Catheter Ablation vs Drug Therapy for Patients With Atrial Fibrillation: The CABANA Trial

Conclusions and Relevance  Among patients with AF, the strategy of catheter ablation, compared with medical therapy, did not significantly reduce the primary composite end point of death, disabling stroke, serious bleeding, or cardiac arrest. However, the estimated treatment effect of catheter ablation was affected by lower-than-expected event rates and treatment crossovers, which should be considered in interpreting the results of the trial.