High Intakes B6, B12: Hip Fracture

Association of High Intakes of Vitamins B₆ and B₁₂ From Food and Supplements With Risk of Hip Fracture Among Postmenopausal Women in the Nurses’ Health Study

Haakon E. Meyer, MD, PhD^1,2,3; Walter C. Willett, MD, DrPH^2,4; Teresa T. Fung, ScD, RD^2,5; et alKristin Holvik, PhD³; Diane Feskanich, ScD⁴

Author Affiliations Article Information

JAMA Netw Open. 2019;2(5):e193591. doi:10.1001/jamanetworkopen.2019.3591

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Conclusions

In this large prospective cohort study of postmenopausal women in the Nurses’ Health Study, we found that a combined high intake of vitamins B₆ and B₁₂ was associated with an increased risk of hip fracture. These findings add to previous studies suggesting that vitamin supplements should be used cautiously because adverse effects can occur.