CVD risk Diabetes

July 31, 2019

Ideal Cardiovascular Health Metrics and Major Cardiovascular Events in Patients With Prediabetes and Diabetes 

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Tiange Wang, MD, PhD¹; Jieli Lu, MD, PhD¹; Qing Su, MD, PhD²; et alYuhong Chen, MD, PhD¹; Yufang Bi, MD, PhD¹; Yiming Mu, MD, PhD³; Lulu Chen, MD, PhD⁴; Ruying Hu, PhD⁵; Xulei Tang, MD, PhD⁶; Xuefeng Yu, MD, PhD⁷; Mian Li, MD, PhD¹; Min Xu, MD, PhD¹; Yu Xu, MD, PhD¹; Zhiyun Zhao, MD, PhD¹; Li Yan, MD, PhD⁸; Guijun Qin, MD, PhD⁹; Qin Wan, MD, PhD¹⁰; Gang Chen, MD, PhD¹¹; Meng Dai, BS¹; Di Zhang, BS¹; Zhengnan Gao, MD, PhD¹²; Guixia Wang, MD, PhD¹³; Feixia Shen, MD, PhD¹⁴; Zuojie Luo, MD, PhD¹⁵; Yingfen Qin, MD, PhD¹⁵; Li Chen, MD, PhD¹⁶; Yanan Huo, MD, PhD¹⁷; Qiang Li, MD, PhD¹⁸; Zhen Ye, MD, PhD⁵; Yinfei Zhang, MD¹⁹; Chao Liu, MD, PhD²⁰; Youmin Wang, MD, PhD²¹; Shengli Wu, MD, PhD²²; Tao Yang, MD, PhD²³; Huacong Deng, MD, PhD²⁴; Donghui Li, PhD²⁵; Shenghan Lai, PhD²⁶; Zachary T. Bloomgarden, MD²⁷; Lixin Shi, MD, PhD²⁸; Guang Ning, MD, PhD¹; Jiajun Zhao, MD, PhD²⁹; Weiqing Wang, MD, PhD¹; for the 4C Study Group

Author Affiliations Article Information

JAMA Cardiol. Published online July 31, 2019. doi:10.1001/jamacardio.2019.2499

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Key Points

Question  Are ideal cardiovascular health metrics (ICVHMs) associated with lower risks of cardiovascular disease among patients with prediabetes or diabetes?

Findings  In this cohort study of 111 765 Chinese participants, compared with participants with normal glucose regulation, participants with prediabetes or diabetes who achieved at least 5 ICVHMs had lower or no increased risks of cardiovascular disease events compared with participants with normal glucose regulation.

Meaning  Our findings emphasize the importance of promoting the adherence to ICVHMs in the prevention of cardiovascular disease events among patients with prediabetes or diabetes.