Colon Cancer

ctDNA Levels May Help Predict Recurrence of Advanced Colon Cancer

CME INFORMATION

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Study Authors: Jeanne Tie, Joshua D. Cohen, et al.; Harry B. Burke, Scott Kopetz

Target Audience and Goal Statement: Oncologists, gastroenterologists, pathologists, hematologists

The goal of this study was to examine if serial post-surgical and post-chemotherapy circulating tumor DNA (ctDNA) analysis could provide a real-time indication of adjuvant therapy efficacy in stage III colon cancer.

Question Addressed:

• Did a correlative biomarker study in patients with stage III colon cancer undergoing standard adjuvant chemotherapy demonstrate an association between post-surgical and post-chemotherapy ctDNA detection and risk of recurrence?/.../