Mesenchymal stem/stromal cells (MSCs) have moved to the forefront of translational medicine given their potential therapeutic applications. With evidence suggesting that MSCs exert their therapeutic impact through the release of extracellular vesicles such as microvesicles and exosomes, MSC-derived exosomes have received substantial interest for their potential use as cell-free therapeutics. In this new wallchart produced by Wiley's Current Protocols in partnership with STEMCELL Technologies, titled “Mesenchymal Stromal Cell-Derived Exosomes: Biogenesis and Cargoes”, we have summarized pathways and processes involved in exosome biogenesis and cargo type and effect.
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