Microbioma and Mind
Can Microbes Manipulate Our Minds? [image: gut] One theory gaining momentum is that members of the gut microbiome actively manipulate our behaviour for their own benefit. NeuroscienceNews.com image is adapted from the University of Oxford news release. [image: Neuroscience News]NEUROSCIENCE NEWSAPRIL 28, 2018 *Summary: Researchers report we may have evolved to depend on our gut bacteria to aid normal brain function, and changes in our microbiome could have effects on our behavior.* *Source: University of Oxford.* Researchers at the University of Oxford have proposed an evolutionary fra... mais »
Male Pill?
Are We Finally Ready for the Male Pill? By Alexandra Sifferlin | Photographs by Isabella Connelley and Bethan Mooney for TIME April 26, 2018 Daniel Dudley, 28, is a busy man. The doctor-in-training is an active hiker, an amateur chef—he’s currently learning Indian cooking—and a proud “father” to two dwarf rabbits whose antics he chronicles under the Instagram handle, *bunnyzaddy*. He’s also at least partially responsible for the creation of a new male contraceptive. Over the last five years, Dudley has volunteered for three separate clinical trials of three different male contracepti... mais »
Prima da Valderês: Ilse Pizzani, 90.
Festejamos no dia 24 a prima da Valderês, filha de um irmão materno, nascida em Rio Bonito, hoje Tangará, em SC, no "vale do Contestado", dez anos depois que a "guerra" já havia terminado. Conversamos sobre a infância da Valderês cuja família também para lá migrou e elas conviveram na idade escolar. As primas Brinde: Ilse, Catharina (filha), Wanyce (irmã da Valderês) e mais alguns braços... mais »
Meu primo Emil Achutti Bered
Meu primo, filho de uma das irmãs de meu pai (tia Emília) junto com seu neto Bruno foram autores da construção de nosso último consultório, e deu Aula Inaugural na PUCRS nesta sema. Aproveitando para lembrar que o consultório anterior - no centro, onde ficamos por 45 anos foi arquitetado pelo irmão mais moço dele Walter.
Science books
Five best science books this week Barbara Kiser’s pick of the top five science books to read this week includes a visceral history of dinosaurs, the world through the nose of a dog and the psychological secrets of the plot twist. Nature | 2 min read [image: Book covers]
Gaia Project
INFOGRAPHIC OF THE WEEK [image: The Gaia spacecraft observes a volume of space 1,000 times larger than previous surveys.]
Dementia: Immune and Endocrine System
Dementia and the immune system It seems that immune cells in the brain known as microglia might be sowing the seeds for the protein plaques associated with Alzheimer’s disease. But the link between dementia and the brain’s immune system is slippery and dynamic. Researchers have struggled to recreate in people the highly successful results they have seen in mice, but a new wave of clinical trials could be on the horizon. Nature | 11 min read The menopause-Alzheimer’s connection “The more we learn about what kicks off and accelerates dementia, the clearer it becomes that we need to take... mais »
Flu native RNA sequenced
Flu virus sequenced in its native form The flu virus has been fully sequenced in its native RNA form for the first time. Before now, all viruses that store genetic material as RNA had been studied by transcribing their genetic sequences into DNA strands. The breakthrough comes thanks to nanopore sequencing technology, which reads RNA strands directly as they snake through a tiny molecular channel. Nature | 4 min read Reference: *bioRxiv* paper
Major Depression Genetics
44 Genetic Risk Factors for Major Depression Identifiedby Neuroscience News Researchers have identified 44 genetic risk factors for major depressive disorder. 30 of the variants are newly discovered. The team reports the genetic basis for MDD is shared with other psychological disorders and all humans carry some of the genetic risk factors identified. Read more of this post *Neuroscience News* | April 27, 2018 at 7:18 am | Tags: MDD | URL: https://wp.me/p4sXNK-cye Comment See all comments
Fusão Primordial de Galáxias
Fusão gigante de galáxias no início do universo intriga astrônomos Por Jéssica Maes, em 26.04.2018 Quase no fim do universo observável, uma imensa colisão cósmica, envolvendo 14 jovens galáxias, pode ter dado lugar a uma megaestrutura, uma das maiores – senão a maior – do nosso universo: um aglomerado de galáxias, gravitacionalmente ligado à matéria escura e nadando em um mar de gás ionizado quente. Por que tudo gira no universo? Usando o Atacama Large Millimeter / Submilimeter Array (ALMA), uma equipe internacional de cientistas descobriu a concentração surpreendentemente densa pres... mais »
Universal Health Care
[image: The Economist] Our cover this week argues that a basic level of* universal health care* is sensible, affordable and practical—including in poor countries. Over half the world goes without essential care; those who get to see a doctor often receive rotten treatment. Universal care would bring broad social benefits, including to the economy. Countries such as Costa Rica and Chile, which spend a fraction of what the United States does and yet enjoy a similar life expectancy, demonstrate the scale of the opportunity Zanny Minton Beddoes, Editor-in-Chief
anticholinergics and dementia
*Recomendado pela AMICOR Berenice Goelzer* Penso que este artigo tenha interesse para Saúde Ocupacional, particularmente para os médicos do trabalho. Olhem o link: http://neurosciencenews.com/dementia-anticholinergics-8884/ Quando li, lembrei-me que os organophosforados inibem a acetilcolinesterase, levando a acúmulo de acetilcolina. ... imagino que pacientes como essas intoxicações sejam eventualmente tratados com medicamentos “anticolinérgicos”, portanto este estudo de side effect deve interessar. Common Class of Drugs Linked to Dementia, Even When Taken 20 Years Before Diagnos... mais »
Placenta and
Growth Curve Content Update 04/26/2018 View in browser [image: Growth Curve]
Human Happiness
Benjamin P. HardyFollow Husband & father of 3. PhD candidate in Organizational Psychology. Author of WILLPOWER DOESN’T WORK. Apr 25 This 75-Year Harvard Study Shows How To Have Lifetime JoyLessons from the longest study on human happiness (TED). For over 75 years, Harvard’s Grant and Glueck study has tracked the physical and emotional health of two groups: - 456 poor people in Boston from 1939 to 2014 (the Grant Study) - 268 graduates from Harvard’s classes of 1939–1944 (the Glueck study) After following these groups and testing them (e.g., blood samples, brain scans) for sever... mais »
Indústria da morte...
*Encaminhado pela AMICOR Dra. Mariana Lopurenço de Lima* foi notícia destaque hoje no site do TRT da 4a Região As perguntas são boas, mas as respostas induzem ao erro. Interessante para conhecer os argumentos falaciosos da indústria do tabaco. E as estratégias de marketing (instituto para jovens etc). https://www.trt4.jus.br/portais/trt4/modulos/noticias/168265 ABRIL VERDE: “O que realmente faz diferença para o produtor é a conscientização de que ele precisa se proteger”, diz presidente do SindiTabaco Iro Schünke, presidente do SindiTabaco No último dia 6 de abril, o Tribunal Regi... mais »
Malaria
How to Wipe Out Malaria for Good *Será esse o caminho, antes de erradicar a miséria e seu cortejo de insalubridades?....* [image: Municipal workers spray chemicals in canal and other worker fumigate slum area to kill mosquito in Kolkata. and malaria on August 9, 2017 in Kolkata.] Municipal workers spray chemicals in canal and other worker fumigate slum area to kill mosquito in Kolkata. and malaria on August 9, 2017 in Kolkata. Saikat Paul—Pacific Press/LightRocket/Getty Images By ERIN M. STUCKEY 5:07 AM EDT IDEAS Stuckey is an epidemiologist and a program officer with the malaria te... mais »
Milky Way
Stellar Effort: Chart of the Milky Way Includes More Than 1 Billion StarsThe second data set release from Europe’s Gaia mission could provide clues to the galaxy’s past and future By Jeremy Hsu on April 24, 2018[image: Stellar Effort: Chart of the Milky Way Includes More Than 1 Billion Stars] In an eagerly anticipated development, astronomers have created the largest and most precise 3-D map of the Milky Way galaxy. The European Space Agency’s $1-billion Gaia mission released its newest data set in April, detailing the positions and motions of more than a billion stars.The Gaia spac... mais »
Life view of cells moving
Incrível vídeo: células se movendo Por Natasha Romanzoti, em 23.04.2018 ------------------------------ Já sabemos há décadas como as células se movem pelos organismos, mas agora temos o primeiro vídeo tridimensional em alta resolução desse processo – e é incrível. A filmagem abaixo mostra uma célula imune se movendo através do ouvido interno de um pequeno peixe-zebra, em tempo real. Os pontos azuis que a célula está engolindo são partículas de dextrano, um polissacarídeo açucarado encontrado em muitas substâncias, de remédios a vinhos a placas dentais.
DNA
Nova estrutura é identificada em DNA de células vivasPor Juliana Blume, em 23.04.2018 Pela primeira vez, cientistas identificaram a existência de uma nova estrutura de DNA nunca antes vista em células vivas. A descoberta foi chamado de “nó torcido” no DNA confirma que nossos complexo código genético é dotado de uma simetria muito mais complexa do que apenas uma estrutura de hélice dupla que todo mundo associa com o DNA. Esta variante molecular afeta como nossa biologia funciona. “Quando a maioria de nós pensa em DNA, pensamos na hélice dupla. Essa pesquisa nos lembra que estruturas ... mais »
Cncer Report
View this email in your browser New report on cancer risk, prevention and survival Launch date announced On 24 May 2018, we will be launching *Diet, Nutrition, Physical Activity and Cancer: a Global Perspective,* our Third Expert Report. This will build on our landmark Second Expert Report from 2007, once again providing a rigorous, systematic, global analysis of the scientific research currently available. We will be launching the new report at a number of conferences including the European Congress on Obesity in Vienna and the the International Society of Behavioral Nutrition and P... mais »
Scale: Geoffrey West
The Key to Everything Freeman Dyson MAY 10, 2018 ISSUE Scale: The Universal Laws of Growth, Innovation, Sustainability, and the Pace of Life in Organisms, Cities, Economies, and Companies by Geoffrey West Penguin, 479 pp., $30.00 Johnny Miller/Unequal Scenes/Thomson Reuters Foundation Ciudad Nezahualcóyotl, part of greater Mexico City, 2016 Geoffrey West spent most of his life as a research scientist and administrator at the Los Alamos National Laboratory, running programs concerned not with nuclear weapons but with peaceful physics. After retiring from Los Alamos, he became director... mais »
William Shakespeare
[image: William Shakespeare, detail of an oil painting attributed to John Taylor, c. 1610.…] William Shakespeare William Shakespeare, the poet, dramatist, and actor who is regarded as the national poet of England and is perhaps the most famous dramatist of all time, died on this day in 1616 in his native town of Stratford-upon-Avon. Estive com Valderês visitando a cidade. Tenho fotos com intenção de apresentar
Período Neolítico
A autêntica revolução foi no período Neolítico [image: A autêntica revolução foi no período Neolítico] [image: share on twitter] [image: share on facebook] [image: share on Flipboard] elpais.com / Guillermo Altares O Neolítico é o período mais importante da história e um dos mais desconhecidos do grande público. Com a adoção da pecuária e da agricultura foram… leia mais
Training Physicians: Nutrition
Stephen Devries, MD: Training Physicians About Nutrition Jennifer Abbasi Article Information JAMA. Published online April 11, 2018. doi:10.1001/jama.2018.1070 Audio(18:54) Training Physicians About NutritiHH Heading an outpatient cardiology clinic early in his career, Stephen Devries, MD, realized that his training did not equip him to adequately respond to his patients’ questions about healthful eating. The preventive cardiologist faced the same dilemma as a weekly heart-health columnist for the *Chicago Sun-Times*. Often, he was stumped by the questions readers sent in about nutritio... mais »
Diabetes mortality: SGLT-2 x DPP-4
Original Investigation April 17, 2018 Association Between Use of Sodium-Glucose Cotransporter 2 Inhibitors, Glucagon-like Peptide 1 Agonists, and Dipeptidyl Peptidase 4 Inhibitors With All-Cause Mortality in Patients With Type 2 DiabetesA Systematic Review and Meta-analysis Sean L. Zheng, BM BCh, MA, MRCP1,2,3; Alistair J. Roddick, BSc4; Rochan Aghar-Jaffar, BMedSci, BMBS, MRCP1,3,5; et al *Question* How do sodium-glucose cotransporter 2 (SGLT-2) inhibitors, glucagon-like peptide 1 (GLP-1) agonists, and dipeptidyl peptidase 4 (DPP-4) inhibitors compare in reducing mortality and cardi... mais »
Acute Uncomplicated Cystitis
April 22, 2018 Nitrofurantoin vs FosfomycinRendering a Verdict in a Trial of Acute Uncomplicated Cystitis Rupak Datta, MD, PhD1; Manisha Juthani-Mehta, MD1 *U*rinary tract infections (UTIs) are common and contribute a significant burden to population health. In the United States, UTIs account for approximately 10 million ambulatory visits and an estimated $2 billion in total costs each year.1,2 Compared with men, women incur a greater burden of disease, with more than half of women experiencing at least 1 UTI during their lifetime.3 Among women aged 18 to 70 years, acute uncomplicate... mais »
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