Friday, March 27, 2020

Viral Load

Does a high viral load 

or infectious dose
make covid-19 worse?

HEALTH 27 March 2020
An illustration of coronavirus particles
An illustration of coronavirus particles
MAURIZIO DE ANGELIS/SCIENCE PHOTO LIBRARY
Does being exposed to more coronavirus particles mean you will develop a more severe illness? Rumours circulating on social media suggest that hospital workers or their household members exposed to a higher “viral load” become sicker than the general population. But emerging research indicates the relationship between infection and covid-19 severity may be more complex – and differ from that of other respiratory illnesses.
The average number of viral particles needed to establish an infection is known as the infectious dose. We don’t know what this is for covid-19 yet, but given how rapidly the disease is spreading, it is likely to be relatively low – in the region of a few hundred or thousand particles, says Willem van Schaik at the University of Birmingham, UK.
Viral load, on the other hand, relates to the number of viral particles being carried by an infected individual and shed into their environment. “The viral load is a measure of how bright the fire is burning in an individual, whereas the infectious dose is the spark that gets that fire going,” says Edward Parker at the London School of Hygiene and Tropical Medicine.



Read more: https://www.newscientist.com/article/2238819-does-a-high-viral-load-or-infectious-dose-make-covid-19-worse/#ixzz6HtpIx7Qg

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