Exercise can suppress signaling within breast cancer cells, which can reduce tumor growth and even kill the cancerous cells, according to a team of Texas A&M researchers from the School of Veterinary Medicine and Biomedical Sciences.
What to Know
During muscle contractions, the muscle releases some factors that kill, or at least decrease the growth, of neoplastic cells and in some cases may play a role in fighting breast cancer.
The factors inherently reside in muscle and are released into the bloodstream. Simple forms of muscle contraction, such as occur when going on a walk or getting up to dance, can release these factors to combat cancer.
It is believed that the risk of breast cancer is decreased with exercise because exercise slows the growth of abnormal cells and that precancerous cells can be destroyed by the body before they start to develop.
Regular exercise could disrupt communication in the cancerous cells so as to stop their growth, and the factors released by exercise may play a role in preventing the development of breast cancer in the first place.
Exercise is not 100% guaranteed to prevent cancer. Some people who work out regularly are still diagnosed with cancer, and there are many confounding factors that affect a person's risk of developing cancer, such as smoking, age, genetics, and comorbidities.
This is a summary of the article, "Myokines Derived From Contracting Skeletal Muscle Suppress Anabolism in MCF7 Breast Cancer Cells by Inhibiting mTOR," published in Frontiers In Physiology in October 2022. The full article can be found on frontiersin.org.
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Injecting ageing monkeys with a ‘longevity factor’ protein called klotho can improve their cognitive function — hinting at possible treatments for neurodegenerative diseases in people. Klotho is a naturally occurring protein whose level in our bodies declines as we age. Rhesus macaques (Macaca mulatta) aged about 22 years — around 65 years in human terms — became better at remembering where food was hidden after receiving klotho. Before the injections, they identified the correct location around 45% of the time, compared with around 60% of the time after injection. The effect lasted for up to two weeks. It is still not clear how injecting klotho has this effect or why it lasts this long.
Nature | 4 min read
Reference: Nature Aging paperQUOTE OF THE DAY
“If you ask people about the model of an innovator, they think of Elon Musk or some old white guy in a lab coat … They don’t think of black people, enslaved, in Jamaica in the 18th century.”
Historian Jenny Bulstrode reveals that an iron-working process that was pivotal to the industrial revolution was developed by enslaved metallurgists in Jamaica and not by the British industrialist who patented it, Henry Cort. (The Guardian | 4 min read)
Reference: History and Technology paper
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Artificial Intelligence and Math
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