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Showing posts with label addiction. Show all posts
Showing posts with label addiction. Show all posts

Monday, December 02, 2019

Pablo Escobar

Escobar, Pablo1993: Colombian criminal Pablo Escobar—who, as head of the Medellín cartel , was arguably the world's most powerful drug trafficker in the 1980s and early '90s—was killed during a shoot-out with authorities. [Did Escobar's prison have a nightclub? Find out that and more in our list of 8 Interesting Facts About the King of Cocaine .]

Thursday, November 28, 2019

Alcoholism

A dose of ketamine could lessen the lure of alcohol

The hallucinogenic drug may help treat addiction by weakening past memories of drinking

beerA single dose of ketamine may cut down problematic drinking. Taken in the right context, the hallucinogenic drug may be able to weaken the pull of the cues that trigger people to drink beer, researchers report November 26 in Nature Communications.
Ketamine’s influence on people’s drinking was modest. Still, the results might be a time when “small effects tell a big story,” says addiction researcher David Epstein of the National Institute on Drug Abuse in Baltimore. “If a seemingly small one-time experience in a lab produces any effects that are detectable later in real life, the data are probably pointing toward something important.”
The study hinges on the idea that addiction, in a way, is a memory disorder. People learn to associate a drug or alcohol with the good feelings it brings. Cues in the world, such as the smell or picture of a beer, can trigger those memories — and cravings. “We’re trying to break down those memories to stop that process from happening, and to stop people from relapsing,” says study coauthor Ravi Das, a psychopharmacologist at University College London./.../

Tuesday, August 27, 2019

Tobbaco Addiction

Less Addictive Cigarettes

JAMA. 2019;322(8):718. doi:10.1001/jama.2019.11369
Eight in 10 smokers favor requiring cigarette manufacturers to lower nicotine levels in cigarettes to make them less addictive, according to a study published by CDC scientists in the American Journal of Preventive Medicine.
Image description not available.
Despite substantial reductions in smoking since the 1960s, smoking remains the leading cause of preventable death in the United States causing an estimated 480 000 deaths annually, according to the authors. Of the two-thirds of smokers who would like to quit, only about 1 in 10 successfully quit each year because of the highly addictive nature of nicotine in cigarettes, they note. To curb this ongoing public health crisis, the US Food and Drug Administration (FDA) proposed a new strategy in 2017: lowering nicotine levels in conventional cigarettes to nonaddictive levels. In March 2018, the FDA took the first step toward enacting the policy issuing an advance notice of proposed rulemaking, which sought comments on and research about the strategy’s potential effects.
According to the CDC’s web-based survey of 4037 US adults, 81% strongly or somewhat favored requirements for nonaddictive levels of nicotine in conventional cigarettes. The policy was nearly universally popular across gender and other subpopulations. More than 80% of both current (80.6%) and former (84.3%) smokers and 71.5% of current noncigarette tobacco product users expressed support for the proposal. A recent simulation study suggested that 13 million smokers would quit within 5 years of the proposed policy’s implementation.
“Lowering nicotine levels in cigarettes could help current smokers quit and make it less likely for future generations to become addicted to these products,” said Corinne Graffunder, DrPH, MPH, director of CDC’s Office on Smoking and Health in a press release.

Sunday, June 23, 2019

collective unconscious

How Jung’s collective unconscious inspired Alcoholics Anonymous

Por
 
aeon.co
5 min
Alcoholics Anonymous (AA) is an international mutual-aid fellowship with more than 2 million members worldwide. It strives to help members ‘stay sober and other alcoholics achieve sobriety’. Despite the fact that studies of its efficacy have been inconsistent, AA has had a significant and long-term effect on the culture of the United States and one of its founders was among Time magazine’s most important people of the 20th century.

Saturday, May 18, 2019

Thursday, February 14, 2019

Opioïdes



Opioïdes, l'hécatombe américaine

Plus de 65 000 Américains ont succombé à des overdoses en 2016, la majeure partie due à des opioïdes, souvent prescrits trop généreusement par des médecins. La crise a été tardivement qualifiée d'«urgence nationale» par Donald Trump
Frank Whitelaw est un adepte du langage cru et des méthodes fortes. Confronté régulièrement à des cadavres, ce «coroner», enquêteur médico-légal du comté d’Essex, situé dans l’État de New York, est aux premières loges pour se rendre compte de l’ampleur de l’hécatombe des opioïdes qui ronge son pays. Alors, l’année dernière, quand il a été invité par la Saranac Lake High School pour évoquer le problème, cet ancien policier habitué des scènes de crimes et des morts violentes n’a pas hésité: sa présentation Powerpoint aurait pour but de réveiller les consciences./.../

Thursday, October 18, 2018

Roteiro da droga

Roteiros da droga e do crime

O texto a seguir, que dá início a este artigo sobre o forte  crescimento das plantações de coca e do consumo de cocaína no mundo e em especial na América do Sul com destaque para o Brasil, provém do livro Guerra en los Andes (Vitor Gomes Pinto – Ed. Abya Yala, Quito, 2a. edición). Há, porém, algumas novidades: uma é o fluxo acelerado e a quantidade das mercadorias transacionadas desde as fronteiras brasileiras de sul a norte; outra é a consolidação da chamada Rota Caipira que levou o porto de Santos a se tornar a base principal da transferência da droga (em geral via países do oeste africano) para a Europa; ainda, o consumo de cocaína e de drogas em geral aumentou bastante na sociedade brasileira e, por último, conforme todas as previsões, deu-se o fortalecimento de potentes grupos criminosos como o PCC, o Comando Vermelho,  que, aliados a carteis colombianos, mexicanos, norte-americanos e italianos, dominaram o comércio ilegal das drogas num negócio multimilionário que nas eleições de 2018 se fez sentir com as notícias de candidatos apoiados pelo crime ganharam substância e representatividade. fora do Brasil, as notícias não são melhores: as plantações de coca explodiram na Colômbia, atingindo níveis nunca vistos.

Sunday, October 14, 2018

rVLPFC

This tiny bit of the brain could offer clues about addiction

It’s responsible for getting you to stop doing things.

New research published this week in the journal Neuron points to a small area of the brain, called the right ventrolateral prefrontal cortex (rVLPFC), as the region responsible for taking in contextual information (like the spider) and using it to update the original plan. “It’s not directly involved. It’s more monitoring the intent to stop, and not actually doing the stopping,” says Kitty Xu, who conducted the research during her doctoral studies at Johns Hopkins. Xu is now a user-experience researcher at Pinterest./.../

Thursday, May 31, 2018

Cocaine in Brain’s Reward Circuit

Cocaine Use Alters Gene Expression in Brain’s Reward Circuit

by Neuroscience News
A new study reveals how cocaine use alters gene expression and provides new insight into the molecular basis of cocaine addiction.

Sunday, May 27, 2018

Dopamine System and Addiction

a woman running

Using animal models, Thanos and his team of researchers found that daily aerobic exercise altered the mesolimbic dopamine pathway in the brain. Dopamine is a key neurotransmitter associated with substance use disorders, playing an important role in reward, motivation and learning.

Monday, January 29, 2018

Glia & Motivation for Drug


Glial Cells Play Key Role in Regulating Motivation for Drug in Heroin Addiction

by Neuroscience News
Researchers report in glial cells, drug induced plasticity can reduce the motivation for heroin. The findings could help develop new treatments for opioid addiction.
Neuroscience News | January 29, 2018 at 5:42 am | Tags: BRG1heroinopioid addiction | URL: https://wp.me/p4sXNK-c4u
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Thursday, December 07, 2017

Opioids


News
What hospitals can do to help keep excess opioids out of communities
Dec 06, 2017 04:12 PM
Guidelines for prescribing opioids following a routine surgery prevented thousands of unnecessary pills from leaving the hospital, a new study finds. Read More