Saturday, October 31, 2015

Novembro Azul: Campanha

Preencha os campos abaixo para

baixar o KIT com as peças da Campanha

Novembro Azul

Halloween

What Trick-or-Treating Tells Us About Human Nature

The annual Halloween tradition of using kids as research subjects has recently seen renewed interest; the appeal is that these real-life examples can offer insights into human behavior

End-of-Life Dementia Costs More Than Heart D,.Cancer

Pauline Anderson

October 30, 2015

The study, which investigated social costs and financial risks faced by Medicare beneficiaries during the 5 years before death, found that healthcare spending for dementia topped $250,000 per person, about 57% more than costs associated with death from other diseases, including cancer and heart disease.

The new analysis, carried out by Amy S. Kelley, MD, Icahn School of Medicine at Mount Sinai, New York, New York, and colleagues, was published online October 27 in the Annals of Internal Medicine.

"This complex analysis lays out the significant health care costs to society and individuals" at the end of life, said Richard J. Hodes, MD, director, National Institute on Aging (NIA), which funded the analysis, in a press release./.../

Telomere and AD

Megan Brooks

October 30, 2015 Shortening a Cause of Alzheimer's Disease?

A new study provides evidence for the first time of a causal relationship between telomere length (TL) and Alzheimer's disease (AD), say investigators from Sweden.

"This is the first study addressing the causal effect of TL on AD," principal investigator Sara Hägg, PhD, docent of molecular epidemiology, Karolinska Institutet, Stockholm, toldMedscape Medical News.

Telomeres are repetitive DNA sequences at the ends of chromosomes that progressively shorten with age. Observational studies suggest that shorter telomeres are associated with shorter life expectancy and greater risk for age-related diseases, including AD. However, these studies could have residual confounding or reverse causation, making it difficult to draw conclusions on whether TL is causally associated with AD./.../

Ageing/Neurology

Long-term aerobic exercise prevents age-related brain deterioration

October 30, 2015

A study of the brains of mice shows that structural deterioration associated with old age can be prevented by long-term aerobic exercise starting in mid-life, according to the authors of an open-access paper in the journal PLOS Biology yesterday (October 29). Old age is the major risk factor for Alzheimer’s disease, like many other diseases, as … more…

A drug-delivery technique to bypass the blood-brain barrier

October 26, 2015

Drug-Delivery-across-Blood-Brain-Barrier-ft

Could benefit a large population of patients with neurodegenerative disorders

Researchers at Massachusetts Eye and Ear/Harvard Medical School and Boston University have developed a new technique to deliver drugs across the blood-brain barrier and have successfully tested it in a Parkinson’s mouse model (a line of mice that has been genetically modified to express the symptoms and pathological features of Parkinson’s to various extents). Their findings, … more…

What happens in the brain when we learn

October 28, 2015

These are isolated cells in the visual cortex of a mouse (credit: Alfredo/Kirkwood (JHU))

Findings could enhance teaching methods and lead to treatments for cognitive problems

A Johns Hopkins University-led research team has proven a working theory that explains what happens in the brain when we learn, as described in the current issue of the journal Neuron. More than a century ago, Pavlov figured out that dogs fed after hearing a bell eventually began to salivate when they heard the bell ring. … more…

Sleep disruptions similar to jet lag linked to memory and learning problems

October 29, 2015

Add good sleep habits to regular exercise and a healthy diet to maximize good memory, scientists advise

Chemical changes in brain cells caused by disturbances in the body’s day-night cycle may lead to the learning and memory loss associated with Alzheimer’s disease, according to a University of California, Irvine (UCI) study. People with Alzheimer’s often have problems with sleeping or may experience changes in their slumber schedule. Scientists do not completely understand … more…

Friday, October 30, 2015

Onde andam as Sulfas?!...

Gerhard Domagk

German scientist

Written by: The Editors of Encyclopædia Britannica

Domagk, Gerhard [Credit: Archiv für Kunst und Geschichte, Berlin]

Gerhard Domagk, (born Oct. 30, 1895, Lagow, Brandenburg, Ger.—died April 24, 1964, Burgberg, near Königsfeld, W.Ger.), German bacteriologist and pathologist who was awarded the 1939 Nobel Prize forPhysiology or Medicine for his discovery (announced in 1932) of the antibacterial effects of Prontosil, the first of the sulfonamide drugs.

Domagk earned a medical degree from the University of Kiel in 1921. After teaching at the universities of Greifswald (1924) and Munich (1925), he became director of the I.G. Farbenindustrie (Bayer) Laboratory for Experimental Pathology and Bacteriology, Wuppertal-Elberfeld. There, inspired by the ideas of Paul Ehrlich, he began testing newly developed dyes ... (100 of 203 words)

Thursday, October 29, 2015

Lifelong memory

Lifelong memories may reside in nets around brain cells

Emily Underwood

Studies suggest key role for perineuronal networks of proteins and sugars in long-term memory.

29/10/1945

Fim do Estado Novo. Renúncia de Getúlio Vargas

Ageing Cities

24 Sep 2015

Arup has launched “Shaping Ageing Cities” – a new report that analyses how ten European cities are responding to ageing.

We are living in the urban and ageing era. In 2050, for the first time in human history, the number of older people will be greater than the number of children under 15 years old. As cities across the globe continue to grow, more people are growing old in housing, streets, communities that often are failing to respond appropriately to ageing populations with specific policies.

How can cities respond to this demographic change and deliver appropriate solutions? This forward-thinking report, undertaken by Arup in collaboration with HelpAge International, Intel ICRI Cities and Systematicaaddresses this global concern through a comparative overview of the performance of 10 European cities.

The report analyses these key issues according to ageing data and observing them under the lenses of society, mobility, built and digital environment and sets up the basis to further investigate the correlation among politics, planning and ageing.

"Cities and urban environments have a fundamental role in defining how to deal with our ageing society. This provides a unique opportunity to influence and design urban environments and social structures in ways that respect, protect and fulfil our rights, including in our older age."

—Stefano Recalcati, Associate, Milan

Shaping Ageing Cities defines a methodology to study ageing in European cities; understanding main features such as transportation, income, outdoor spaces, building design, social inclusion, ICT and health services in order to apply this experience to the growing market related to city-making.

Download the report (.PDF, 11.5MB)

Wednesday, October 28, 2015

microbiota e aterosclerose

Academia Global de Aterosclerose

Função da microbiota na aterosclerose

A microbiota intestinal pode ser um potencial alvo terapêutico no controle de doenças metabólicas

Botox na FA

Botox pode evitar fibrilação atrial após cirurgia de revascularização

Injeções nos coxins de gordura em volta do coração reduzem de modo considerável incidências de fibrilação atrial.

Cidadania no Século XXI

Fernando Savater (link para dados sobre o conferencista)

A educação do cidadão no século XXI (resumo)

por

Luciana Thomé - Porto Alegre - 26.10.2015

Para o conferencista, no ensino da ética, três virtudes são essenciais e devem ser reforçadas:

- a coragem para poder viver: pois vivemos diante da morte, das dificuldades e das ameaças, e não se pode viver eticamente sem coragem;

- a generosidade para poder conviver: pois viver com outros exige, de alguma maneira, ceder, e precisamos limitar nossos desejos no choque com os demais;

- e a prudência para sobreviver: pois a vida está cheia de armadilhas e de riscos, e exercer o bem é, muitas vezes, arriscado. Mas o martírio não serve de nada sem proveito.

Primeira página jornais

Enviado por meu primo Nilo Sérgio Cechella

UMA BANCA INTERNACIONAL DE JORNAIS.

ON LINE
!
GRÁTIS
!

http://www.hhmmss.com/

Stephen Leeder

Enviado pela AMICOR Maria Inês Reinert Azambuja

Australian academics seek to challenge 'web of avarice' in scientific publishing

In the wake of editor-in-chief Stephen Leeder’s sacking from the Medical Journal of Australia, academics are challenging the control of a select group of publishing houses over scientific journals

Mitchell Library Reading Room at the State Library of New South Wales

Leeder told Guardian Australia he still felt “pretty beaten up” by the MJA experience, knowledge and scholarly information had gone from being a public good to a “commercial, tradable commodity”.

“The whole academic publishing industry is a gigantic web of avarice and selfishness, and the academic community has not engaged to the extent it perhaps should have to stop it,” Leeder said.
“Scholarly publishing is a bit like the Trans-Pacific Partnership Agreement. It’s not totally clear what the hell is going on, but you can be sure someone is making a hell of a lot of money from it.”/.../

Tuesday, October 27, 2015

Microglia

Rise of the Microglia

New research shows that the resident immune cells of the brain are involved in both development and disease

By Diana Kwon | October 23, 2015

Microglia, the immune cells of the brain, have long been the underdogs of the glia world, passed over for other, flashier cousins, such as astrocytes. Although microglia are best known for being the brain’s primary defenders, scientists now realize that they play a role in the developing brain and may also be implicated in developmental and neurodegenerative disorders. The change in attitude is clear, as evidenced by the buzz around this topic at this year’s Society for Neuroscience (SfN) conference, which took place from October 17 to 21 in Chicago, where scientists discussed their role in both health and disease.

Activated in the diseased brain, microglia find injured neurons and strip away the synapses, the connections between them. These cells make up around 10 percent of all the cells in the brain and appear during early development. For decades scientists focused on them as immune cells and thought that they were quiet and passive in the absence of an outside invader. That all changed in 2005, when experimenters found that microglia were actually the fastest-moving structures in a healthy adult brain. Later discoveries revealed that their branches were reaching out to surrounding neurons and contacting synapses. These findings suggested that these cellular scavengers were involved in functions beyond disease.

The Brain’s Sculptors
The discovery that microglia were active in the healthy brain jump-started the exploration into their underlying mechanisms: Why do these cells hang around synapses? And what are they doing?/.../

Sunday, October 25, 2015

Maranhão em Shanghai

Visita ao Prof. GE Junbo, Presidente da Sociedade Chinesa de Cardiologia, em Shanghai como Prof. Visitante no 10th Hospital da Tongji University por 1 mês.