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Saturday, October 24, 2015


Improving learning and memory in aged mice with cholesterol-binding membrane protein
October 22, 2015

SynCav1 gene delivery enhances granule cell neuron dendritic arborization (neuron branching in adult mice. Scale bar: 20 micrometers (credit: Chitra D. Mandyam et al./Biological Psychiatry) Using gene therapy to increase a crucial cholesterol-binding membrane protein called caveolin-1 (Cav-1) in neurons in the hippocampus* of the brain improved learning and memory in aged mice, according to findings from a new study led by scientists at The Scripps Research Institute (TSRI), the Veterans Affairs San Diego Healthcare System (VA) and University of … more…

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