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Thursday, August 07, 2008

IV antihypertensive clevidipine approved in the US

IV antihypertensive clevidipine approved in the US: "Parsippany, NJ - The Medicines Company has announced that the US FDA has approved its intravenous antihypertensive clevidipine (Cleviprex), which is the first new IV drug for high blood pressure in 10 years [1].
Clevidipine is a new calcium-channel blocker, which has shown promise in several studies, including in severe acute hypertension in the emergency department and in the setting of perioperative blood-pressure management. Doctors presenting these trials, as previously reported by heartwire, said the advantages of clevidipine over current drugs used for acute hypertension—such as sodium nitroprusside, labetalol, and nicardipine—are that it is easy to titrate and has an ultrashort half-life of less than one minute."/.../

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