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Saturday, January 20, 2024

3.172 - AMICOR (26)

 3.172 AMICOR (26) seleções da semana

#com Dra. Valderês A. Robinson Achutti (*13/06/1931+15/06/2021)

Passeando pela Nova Zelândia - logo após o Congresso Mundial - quando recebi o Prêmio Mundial de Cardiologia, em Sidney, na Austrália.

#Re-Publicando apresentações minhas, antigas

#    Neurosciences News

Gut-Brain Network for Sugar and Fat Cravings Discovered

#The Marginalian (Maria Popova)

Elevating Resolutions for the New Year Inspired by Some of Humanity’s Greatest Minds

Elevating Resolutions for the New Year Inspired by Some of Humanity’s Greatest Minds

What if we could augment the bucket-list of typical New Year’s resolutions, dominated by bodily habits and pragmatic daily practices, with higher-order aspirations — habits of mind and spiritual orientations borrowed from some of humanity’s most timelessly rewarding thinkers? After last year’s selection of worthy resolutions inspired by such luminaries as Seneca, Maya Angelou, Bruce Lee, and Virginia Woolf, here is another set for the new year borrowed from a new roster of perennially elevating minds.

#Happy Public Domain Day 2024!

January 1, 2024

#Viva dia 19/01/2024 aniversário (102 anos) de nossa amiga e vizinha, a Professora Marila Fay Azambuja. Nos conhecemos a partir do saudoso amigo Pe Ernesto Greiner, cuja lembrança aflora juntamente, pois ele também estaria comemorando, se por aqui ainda estivesse, não somente em nossa memória...


#A Teoria das Cordas, de um jeito que você vai entender!

#Medscape. Cardiology

Carolyn Crist 

#Our World in Data

Explore our featured work

It’s flu season — how many people die from the flu each year?

Seasonal flu is a contagious illness caused by the influenza virus. It kills around 400,000 people on average each year.

The death toll has been even higher when new influenza strains have evolved and led to large flu pandemics. For instance, it’s estimated that the Spanish flu pandemic of 1918–1920 killed at least 17 million people, and possibly many more, as the chart shows.

Outside of these flu pandemics, the risk of dying from flu has declined substantially over time thanks to improvements in sanitation, healthcare, and vaccination.

But the burden of influenza remains high because many countries have an aging population and lack access to healthcare and sanitation.

In this article, we look into these developments in detail: how many people die from influenza around the world, how this has changed over time, and why.

Read the article
Ocean plastics: How much do rich countries contribute by shipping their waste overseas?

Of the plastic that enters the oceans from land, more than 80% comes from rivers in Asia.

Only a small amount comes from rivers across Europe and North America — about 5% of the global total. This would suggest that the world’s richest countries don’t contribute much to the problem of plastic pollution.

But one objection to these numbers is that they only look at the plastic that is emitted domestically. They don’t consider the fact that many countries export plastic waste overseas, which could potentially lead to a large indirect impact on ocean pollution.

In this article, we use global data to understand the scale of the plastic waste trade and where this waste ends up. In the end, we estimate that a few percent — possibly up to 5% — of the world’s ocean plastics could come from rich countries exporting their waste overseas.

Read the article
Death rates from cardiovascular diseases have declined in many countries
The world faces two energy problems

The mission of Our World in Data is to make data and research on the world’s largest problems understandable and accessible.

We are a nonprofit, building Our World in Data as a public good that’s freely available to everyone. Help us do more by supporting us with a donation.

#National Science Foudation

R/V Nathaniel B. Palmer at Davis Station anchorage with aurora borealis light show overhead

Nathaniel B. Palmer at Davis Station anchorage

In this image, the research vessel Nathaniel B. Palmer is docked at Davis Station anchorage in Antarctica with an aurora australis light show overhead. The ship is operated as part of the U.S. Antarctic Program, managed by NSF.



#Instituto de Cardiologia Dante Pazzanezi
Nesse sábado, 13 de janeiro, às 19h, o monumento ao Cristo Redentor será iluminado em azul para celebrar os 70 anos do Instituto Dante Pazzanese de Cardiologia - IDPC



Saturday, January 13, 2024

3.171 - AMICOR (26)

 3.171 - AMICOR (26) 

#Com Dra. Valderês A. Robinson Achutti (*13/06/1931 +15/06/2021)

No século passado, nas Montanhas Rochosas, no Canadá.

#Re-Publicando apresentações minhas antigas
Tabagismo e Gravidez
Congresso Brasileiro de Cardiologia de 2008 - Curitiba Link

#History Channel

 
January 11
1964
U.S. Surgeon General announces definitive link between smoking and cancer
United States Surgeon General Luther Terry knew his report was a bombshell. He intentionally chose to release it on January 11, 1964, a Saturday, so as to limit its immediate effects on the stock market. It was on this date that, on behalf of the U.S. Government, Terry announced a definitive link be... read more

#Med Page Today

A computer rendering of a patient who is receiving focused ultrasound

Aducanumab (Aduhelm) infusions combined with focused ultrasound led to lower cerebral amyloid-beta levels in Alzheimer's disease, a proof-of-concept trial showed.

The investigational treatment involved creating an opening in the blood-brain barrier with MRI-guided focused ultrasound to boost drug delivery./.../


#World Heart Federation


# Arquivos Br. de Cardiologia
Paulo Sérgio Veiga Jardim and  Thiago Jardim 2017, 108 (53-59)

Paper Thumbnail
Multiprofessional Treatment of High Blood Pressure in Very Elderly Patients
View PDF ▸ Download PDF ⬇

#IHME

IHME Updates texts with IHME logo to the right
Antimicrobial resistance major threat in Africa   


Over 1 million people died in the WHO African region in 2019 due to bacterial antimicrobial resistance (AMR) in 2019, according to a new study from The Lancet. The burden of AMR mortality is higher in low-income settings, revealing stark health care inequalities across the region. 


AMR deaths have surpassed HIV/AIDS and malaria tolls, emphasizing a critical public health shift as well as a shift in health care priorities. Lower respiratory and thorax infections are a leading cause of death in the WHO African region, and AMR accounts for 48% of these deaths. 

The study identified four major pathogens responsible for 100,000 deaths each:
  • Streptococcus pneumoniae
  • Klebsiella pneumoniae
  • Escherichia coli
  • Staphylococcus aureus
Read the research
Researchers Authia Gray and Dr. Yewande Alimi share insights from this AMR study on a recent episode of the Global Health Insights podcast.
 
Watch the episode
Top Stories
Shibuya, Japan skyline
Cancer rates rising in Asian countries  

New GBD data shows rising cancer rates in Asia, with 9.4 million new cases and 5.6 million deaths in 2019, led by India, China, and Japan. Driven by risk factors including alcohol, smoking, and particulate matter pollution, this escalating health threat requires urgent action.

Read the research→
Farm in Ella, Sri Lanka
Mysterious kidney failure among farmers  

Young and otherwise healthy agricultural workers are developing kidney failure in global hot zones, reports Think Global Health. “There’s something substantial going on,” says Theo Vos, a researcher at IHME.

Read the story→
IHME in the News
Flag of India in a blue sky
India registered 9.3 lakh cancer deaths, second highest in Asia: Lancet Study (Times of India)
» India registered about 12 lakh new cancer cases and 9.3 lakh deaths in 2019, becoming the second largest contributor to the disease burden in Asia for that year, according to a new study published in The Lancet Regional Health Southeast Asia journal.
A pile of surgical masks
Long COVID is a double curse in low-income nations — here’s why (Nature)
» “The main story about long COVID in low- and middle-income countries is that there are relatively few studies,” says Theo Vos, an epidemiologist at the Institute for Health Metrics and Evaluation in Seattle, Washington. “But wherever people have looked at it, they find it.”
Salvando a los niños 🚸 de las infecciones resistentes a los antibióticos 💊   El aumento del uso de antibióticos está causando que encontremos más bacterias que son resistentes a estos antibióticos!!! Dada la carga que suponen los diferentes países, los síndromes infecciosos y las combinaciones de patógenos y medicamentos, la resistencia a los antimicrobianos representa una amenaza sustancial para la salud en las Américas.
LinkedIn post of the week 

Salvando a los niños 🚸 de las infecciones resistentes a los antibióticos 💊 

El aumento del uso de antibióticos está causando que encontremos más bacterias que son resistentes a estos antibióticos!!! Dada la carga que suponen los diferentes países, los síndromes infecciosos y las combinaciones de patógenos y medicamentos, la resistencia a los antimicrobianos representa una amenaza sustancial para la salud en las Américas.

— Catia Cilloniz
Senior Researcher at Hospital clinic of Barcelona
Associate Professor at Universitat of Barcelona/CIBERES
What We’re Reading
Latin America’s health systems are falling behind the rest of the world, WHO warns » The pandemic, persistent inequality, outdated technology and the consequences of climate change have put progress into reverse. (The Telegraph)

As maternal care in Wyoming dwindles, tribal clinics are building up resources for support » Obstetric services have shrunk elsewhere in Wyoming's Fremont County. Tribal patients have greater options. (The 19th News)
 
Featured Datasets

#Quanta Magazine

AGING | ALL TOPICS

 

Cells Across the Body Talk to Each Other About Aging

By VIVIANE CALLIER

Biologists discovered that mitochondria in different tissues talk to each other to repair injured cells. When their signal fails, the biological clock starts winding down.

Read the blog

INFORMATION THEORY

 

‘Magical’ Error Correction Scheme Proved Inefficient

By BEN BRUBAKER

Locally correctable codes need barely any information to fix errors, but they’re extremely long. Now we know that the simplest versions can’t get any shorter.

Read the article


Related: 
Researchers Defeat Randomness
to Create Ideal Code

By Mordechai Rorvig (2021)

MATERIALS SCIENCE

 

New Kind of Magnetism Spotted in an Engineered Material

By MICHAEL GRESHKO

In an atomically thin stack of semiconductors, a mechanism unseen in any natural substance causes electrons’ spins to align.

Read the blog


Related: 
Meet Strange Metals: Where Electricity
May Flow Without Electrons

By Charlie Wood (2023)

Q&A

 

The Theorist Who Sees Math in Art, Music and Writing

Interview by LEILA SLOMAN;
Video by CHRISTOPHER WEBB YOUNG
& EMILY BUDER

The links between math and art have been explored for millennia. Sarah Hart is now turning a mathematical eye to literature.


Read the interview

Watch the video

QUANTA SCIENCE PODCAST

 

Even Synthetic Life Forms With a Tiny Genome Can Evolve

By YASEMIN SAPLAKOGLU;
Podcast hosted by SUSAN VALOT

By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.


Listen to the podcast

Read the article

 

COMPUTER SCIENCE

‘Magical’ Error Correction Scheme Proved Inherently Inefficient

By BEN BRUBAKER
Locally correctable codes need barely any information to fix errors, but they’re extremely long. Now we know that the simplest versions can’t get any shorter.

Read article

#


Top 10 Most Read Pieces from 2023



#MEDSCAPE

Megan Brooks

DISCLOSURES 

Proper care of teeth and gums may offer benefits beyond oral health, including improving brain health, new research suggests.

In a large observational study of middle-aged adults without stroke or dementia, poor oral health was strongly associated with multiple neuroimaging markers of white matter injury.

"Because the neuroimaging markers evaluated in this study precede and are established risk factors of stroke and dementia, our results suggest that oral health, an easily modifiable process, may be a promising target for very early interventions focused on improving brain health," wrote the authors, led by Cyprien Rivier, MD, MS, with the Department of Neurology, Yale University School of Medicine, New Haven, Connecticut.

The study was published online on December 20, 2023, in Neurology.

#Nature aging

Cerebrospinal fluid proteomics in patients with Alzheimer’s disease reveals five molecular subtypes with distinct genetic risk profiles

Abstract

Alzheimer’s disease (AD) is heterogenous at the molecular level. Understanding this heterogeneity is critical for AD drug development. Here we define AD molecular subtypes using mass spectrometry proteomics in cerebrospinal fluid, based on 1,058 proteins, with different levels in individuals with AD (n = 419) compared to controls (n = 187). These AD subtypes had alterations in protein levels that were associated with distinct molecular processes: subtype 1 was characterized by proteins related to neuronal hyperplasticity; subtype 2 by innate immune activation; subtype 3 by RNA dysregulation; subtype 4 by choroid plexus dysfunction; and subtype 5 by blood–brain barrier impairment. Each subtype was related to specific AD genetic risk variants, for example, subtype 1 was enriched with TREM2 R47H. Subtypes also differed in clinical outcomes, survival times and anatomical patterns of brain atrophy. These results indicate molecular heterogeneity in AD and highlight the need for personalized medicine.

#World Congress of Cardiology

World Congress of Cardiology: Showcase your science!
 

#AMRIGS


# Popular Mechanics