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Thursday, January 24, 2013

super-bug


The Future of Antibiotics and Resistance

Brad Spellberg, M.D., John G. Bartlett, M.D., and David N. Gilbert, M.D.
N Engl J Med 2013; 368:299-302January 24, 2013DOI: 10.1056/NEJMp1215093
Article
References
Audio Interview
Interview with Dr. Robert Moellering on the evolution of antibiotic resistance and strategies for combating it.
Interview with Dr. Robert Moellering on the evolution of antibiotic resistance and strategies for combating it. (20:22)
In its recent annual report on global risks, the World Economic Forum (WEF) concluded that “arguably the greatest risk . . . to human health comes in the form of antibiotic-resistant bacteria. We live in a bacterial world where we will never be able to stay ahead of the mutation curve. A test of our resilience is how far behind the curve we allow ourselves to fall.”1
Traditional practices in infection control, antibiotic stewardship, and new antibiotic development are cornerstones of society's approach to combating resistance and must be continued. But the WEF report underscores the facts that antibiotic resistance and the collapse of the antibiotic research-and-development pipeline continue to worsen despite our ongoing efforts on all these fronts. If we're to develop countermeasures that have lasting effects, new ideas that complement traditional approaches will be needed./.../

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