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Monday, July 24, 2017

Necroptosis, known as RIPK1, RIPK3 and MLKL


Image shows a diagram of an alzheimer's brain slice.
Summary: A new Nature Neuroscience study provides evidence that necroptosis is linked to cognitive decline and severity of Alzheimer’s disease. The finding that necroptosis is activated in Alzheimer’s provides a plausible mechanism that underlies the neuron loss associated with the disease.
Source: Arizona State University.
First of its kind study may lead to new era of Alzheimer’s drug discovery and therapeutic targets.
Alzheimer’s disease tragically ravages the brains, memories and ultimately, personalities of its victims. Now affecting 5 million Americans, Alzheimer’s disease is the sixth leading cause of death in the U.S., and a cure for Alzheimer’s remains elusive, as the exact biological events that trigger it are still unknown./.../

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