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Saturday, November 18, 2023

3.163 - AMICOR (26)

 3.163 AMICOR (26) em construção

#Com Dra. Valderês A. Robinson Achutti (*13/06/1931+15/06/2021)

Em Machu-Pichu 14/11/1977 (Peru)

#Republicando artigos Antigos meus

AFINAL, QUEM SOMOS NÓS?
Aloyzio Achutti. Médico.

Vários pretextos justificam a pergunta. Nossa identidade aparente como indivíduos independentes - algumas vezes fragilizados, outras arrogantes - precisa ser repensada. Não passamos de um dos elementos de uma enorme rede interdependente que se entrelaça e se estende, à custa de trocas e de serviços de iguais, de muitos outros seres, e com o ambiente onde vivemos. Estamos neste mundo naturalmente globalizados, não  esquecendo também nossas outras dimensões e relações cósmicas.
Nossa curta visão desarmada e imediatista é pobre e ingênua, pois facilmente nos iludimos colocando o começo e o fim de tudo em nos mesmos, em nosso tempo e nosso espaço corporal.
Poucas gerações para trás e já não conhecemos mais ninguém da família. É preciso um esforço científico para aceitar nossa inserção como um simples elo a mais, numa cadeia com cerca de mais de duzentos milhões de anos, fruto da evolução vital a partir de bactérias primitivas, ao recuarmos mais três bilhões de anos.
Não precisamos ir tão longe. Alimentamo-nos, vestimos e andamos com produtos de uma cadeia interminável e interdependente, onde alguém plantou, cuidou da semente ou do animal, preparou a terra que foi adubada por mais alguém, o fruto foi transportado para o mercado onde alguém mais o comercializou, outro o controla, faz propaganda, cobra impostos, limpa o ambiente, cuida da segurança e da ordenação social, e assim por diante. Embora quase todos visíveis e palpáveis, não nos damos conta desta cadeia interminável de agentes e coisas de nosso dia a dia.  
Fica mais complicado quando nos lembram ser maior o número de germes (dez trilhões) em nosso corpo, do que de células (um trilhão) que o compõe. Embora não vejamos os micro-organismos a olho nu, sem eles não conseguimos viver. Eles processam nossos alimentos até fazê-los assimiláveis e úteis para nossas células, elaboram vitaminas, enviam-nos mensagens, modulam nosso sistema imunitário, mantém o equilíbrio na selva onde estamos mergulhados, protegem-nos de intrusos, recolhem nossos restos e remendam nossos estragos, mas levam a pecha de inimigos que precisam ser destruídos.
São nossos genes e os dos germes nossos amigos que comandam todas as funções vitais. Enquanto nossas células usam cerca de trinta mil genes, eles dispõem de cem vezes mais e estão constantemente em interação conosco, inclusive oportunizando trocas deste material genético. Assim é que, conforme alguns cientistas somos de um a no máximo dez por cento humanos...

Para melhor viver e compreender tantas questões polêmicas, como a do controle da venda de antibióticos para evitar a resistência bacteriana, a da proteção do equilíbrio ambiental, e a do convívio dentro desta extensa e conturbada colônia humana, é preciso pensar na resposta para a pergunta sobre quem realmente somos procurando uma inserção mais compatível no contexto global. 

#TIME

Introducing the TIME100 Climate

Today we launched the TIME100 Climate list of the most influential people shaping how businesses tackle climate change. To identify the true change-makers, TIME’s editors spent months with our in-house climate experts at TIME CO2 to vet nominations from across the economy and around the globe. In total, the list represents individuals from 28 different countries.

In line with the latest scientific and economic thinking, we prioritized nominees from five systems most crucial to change: energy, nature, finance, culture, and health. Unsurprisingly, an overwhelming number of individuals are making waves in transforming our world’s energy system—the largest source of fossil fuel emissions. It was also fascinating to learn about the many cultural initiatives taking place, from Billie Eilish’s push to decarbonize her music to Francis Kéré's influential sustainable architecture. And while there are fewer people featured in the health space, it’s an area that’s only going to become more critical to address—not just because of the industry’s emissions contribution but because it’s clear rising temperatures are already affecting our wellbeing.

READ MORE »
WHAT ELSE TO KNOW
Inside COP28’s Big ‘Experiment’

What happens when you put a fossil fuel executive in charge of solving climate change? That’s the question TIME’s Justin Worland tackles in his profile of Sultan Al Jaber who is presiding over the U.N. COP28 climate conference to be held in Dubai next month.

READ MORE »
​​Affordable Carbon Capture?

My colleague Alejandro De La Garza reports on a new breakthrough in carbon removal technology from Graphyte. The Gates-backed startup that claims to have found a way to trap carbon emissions and store them underground for just $100/ton—considered to be the cost threshold to make this technology successful.

READ MORE »
Don’t Believe the Hype

A new paper published in scientific journal Cell challenges the hype around high-profile oceans plastics clean program, saying that we need to prioritize reductions of upstream plastic production instead.

READ MORE »
The Australian Open

Australia is offering residency to people from the low-lying Pacific Island nation of Tuvalu who have been affected by climate change in what could be a global first for recognizing the rights of climate refugees.

READ MORE »
No Escape

Climate change is hitting every part of Americans' daily lives, according to the latest U.S. National Climate Assessment. This is “unequivocally” the result of fossil fuel pollution it says.

READ MORE »

This edition was by Aryn Baker, with the data point by Kyla Mandel, and edited by Kyla, and Elijah Wolfson. We welcome any feedback at climate@time.com.


#Le TEMPS

Le fait du jour: Emmanuel Macron fait un clin d’œil
européen à la Suisse

Peter Klaunzer/Keytone via AP

Peter Klaunzer/Keytone via AP

Pourquoi c’est important: Emmanuel Macron s’est adressé aux plus méfiants des
Suisses envers l’Europe lors du premier jour de sa visite d’Etat: «Vous ne le savez
peut-être pas encore, mais vous êtes des Européens!». Plusieurs points précis ont été
abordés à Berne, des relations européennes à la fuite des soignants français. 
Ce qu’il faut en retenir

#Delanceyplace

Today's selection -- from Your Brain on Art: How the Arts Transform Us by Susan Magsamen and Ivy Ross. The physiological impact of music on the human body:

“A cardiologist [at Stanford] named Sean Wu had been puzzling over a question about the [heart]'s structure. He wanted to generate heart tissue in the lab in order to create models that would help explain certain cardiac diseases. Eventually, he hoped to be able to create heart patches for patients with weak cardiac walls or with damage from heart attacks. 


“With more than an estimated 37 trillion human cells in our body to work with, scientists are having excellent success generating human tissue in the lab, for everything from brains and bladders to muscle and skin. This new field known as biomaterial design is merging the disciplines of materials engineering and biology in order to grow tissue outside of the body in a lab. 


“Heart cells are special, though. First, they are incredibly complex and challenging to create. Heart cells are also densely packed, which allows them to work in tandem and beat. If they are designed too far apart they won't sync. Too close together, they could smother and die. And so, from an engineering perspective, hearts are the Taj Mahal, the Empire State Building, of organs. You may imagine what you want to build, but you need incredible structural engineering to make it happen. 


“A colleague at Stanford, an acoustic bioengineer named Utkan Demirci, had an idea for Wu. Move the heart cells with sound. Demirci is among a growing number of biomedical researchers tapping into aesthetics, like sound waves, to design cellular structures. Because sound waves move molecules, they can travel through different media--like solids, gels, liquids, and gases--made of molecules. They are versatile. In this case, Demirci put heart cells in a gelled substance, and by tweaking the acoustics he created different sizes and shapes of sound waves (imagine a small ripple amping up into a tidal wave). The cells rode the waves across the gel and into the extraordinary patterns. 


“As Demirci triggered acoustic waves on a microscale, he and Wu watched the heart cells dance into patterns. They could adjust the patterns within seconds by tweaking the acoustics. ‘You change the frequency and amplitude, and the cells move into a new spot right in front of your eyes,’ Wu said in 2018. 


“The work Demirci and Wu were tapping into is called cymatics--the science of visualizing audio frequencies. This process was discovered by Swiss medical doctor and pioneer Hans Jenny, who coined the term and published the first volume on the topic in 1967. Jenny explained in his book Cymatics: A Study of Wave Phenomena and Vibration that ‘acoustic effects of sound waves is not an unregulated chaos. It is a dynamic but ordered pattern.’ 

Resonance made visible with black seeds on a harpsichord soundboard

“After their discovery, Stanford University tweeted out the quilt-like image and asked: Is it art or is it science? 


“It is, wonderfully, both. Researchers are removing the ‘or’ to make it ‘and.’ Art and science together are potent medicine, capable of radically transforming our physical health. 

“Think about this experiment the next time you feel moved by your favorite song. You are literally changed, on a cellular level, by aesthetics. In the case of the red quilt, sound caused heart cells to move. All stimuli that we encounter--visual, auditory, somatosensory, gustatory, olfactory, and others--change the structure and function of cells within our brains and bodies. They do so in fundamental ways, including altering cell cycle, proliferation, viability, and binding of hormones. And when we make those aesthetic inputs multidimensional, we open the door for healing to occur. 


“One of the most important developments in the arts-meets-science approach to physical health has been the ways in which researchers have begun to identify key neurobiological mechanisms. Mechanisms are the many chemical and physical activities that underlie how things work in your body. Digesting your latest meal, for instance, happens because of multiple mechanisms, from saliva production in the mouth to chemicals in the stomach to the ways nutrients are absorbed. We understand how and why the body digests food. And by better understanding the mechanisms engaged when using the arts, practitioners are able to design and enhance interventions with greater precision. 


“In a 2021 study published in the journal Lancet Psychiatry, Daisy Fancourt and her team studied the mounting evidence for the benefits of leisure activities, such as participating in the arts, on human health. They identified and mapped more than 600 mechanisms--from improving respiratory and physical function to enhancing immune function and developing group values--that occur both in our individual bodies, as well as at the group and societal level. These mechanisms are broadly grouped into psychological, biological, social, and behavioral. 


“Another critical point that Daisy and her fellow researchers made in this study about arts and mechanisms is related to the idea of complexity science. ‘People have often viewed the field of arts and health as needing to operate like the field of pharmacology,’ Daisy explained. For example, a drug has an active ingredient with maybe one or two biological mechanisms of action and these have predictable outcomes. ‘Whereas, our clear point in this paper is that in complexity science, you recognize that there are hundreds of ingredients, hundreds of mechanisms. They all work bidirectionally, not just unidirectionally and they're moderated by external factors.’ 


“This summarizes quite nicely why the arts have such a potent effect on our health: Whereas a pharmacological treatment works on one, maybe two, pathways, the arts have the ability to trigger hundreds of mechanisms that work in concert. 


“‘This point is really important to get across,’ Daisy says, ‘because sometimes people have seen the complexity and the 'messiness' of arts and health mechanisms as a weakness where in fact, it is the very heart of why the arts work. It's just that we've been applying an overly simplistic biomedical lens on something that needs to be seen with a complexity science lens.’


“Today, the arts are being used in at least six distinct ways to heal the body: as preventative medicine; as symptom relief for everyday health issues; as a treatment or intervention for illness, developmental issues, and accidents; as psychological support; as a tool for successfully living with chronic issues; and at the end of life to provide solace and meaning."

Your Brain on Art: How the Arts Transform Us

#

REINFORCEMENT LEARNING | ALL TOPICS

 

AI System Beats Chess Puzzles With ‘Artificial Brainstorming’

By STEPHEN ORNES

By bringing together disparate approaches, machines can reach a new level of creative problem-solving.

Read the article

Quanta is conducting a series of surveys to better serve our audience. Take our newsletter subscriber survey and you will be entered to win free Quanta merchandise.

ASTROPHYSICS

 

Rogue Worlds Throw Planetary Ideas Out of Orbit

By CHARLIE WOOD

Scientists have recently discovered scores of free-floating worlds that defy classification. The new observations have forced them to rethink their theories of star and planet formation.

Read the article


Related: 
JWST Spots Giant Black Holes
All Over the Early Universe

By Charlie Wood

COMBINATORICS

 

The Astonishing Behavior of Recursive Sequences

By ALEX STONE

Some strange mathematical sequences are always whole numbers — until they’re not. The puzzling patterns have revealed ties to graph theory and prime numbers, awing mathematicians.

Read the blog


Related: 
The Connoisseur
of Number Sequences

By Erica Klarreich (2015)

IMMUNOLOGY

 

During Pregnancy, a Fake ‘Infection’ Protects the Fetus

By ANNIE MELCHOR

Cells in the placenta have an unusual trick for activating gentle immune defenses and keeping them turned on when no infection is present. It involves crafting and deploying a fake virus.

Read the blog
 

Around the Web

Put Your Heads Together
A new genetic analysis of starfish reveals that they are all head, no body. This surprising finding could offer hints about why they evolved to have such unique radial symmetry, reports Lori Youmshajekian for Scientific American. The physicist Nikta Fakhri believes that starfish hold clues to even deeper biological mysteries. In 2023, Charlie Wood interviewed Fakhri for Quanta about how studies of starfish helped her see how physical phenomena such as symmetry breaking define life.

A Mounting Meltdown
Glaciers in Greenland are melting twice as fast as they were a few decades ago, reports Delger Erdenesanaa for The New York Times. They have shrunk more than 35% in volume since 1978. Melting at the poles is locked in a feedback loop with global climate change: As the ice melts, it reflects less of the sun’s energy back to space. In 2020, Shannon Hall wrote for Quanta about an Arctic mission to study the dynamics of the melting ice.

#The Universe in verse

The Universe in Verse: Regina Spektor Reads “Theories of Everything” by Astronomer, Poet, and Tragic Genius Rebecca Elson

The Universe in Verse: Regina Spektor Reads “Theories of Everything” by Astronomer, Poet, and Tragic Genius Rebecca Elson

In her haunting ode to the Hubble Space Telescope, Adrienne Rich serenaded “the ex-stasis of galaxies / so out from us there’s no vocabulary / but mathematics and optics / equations letting sight pierce through time / into liberations, lacerations of light and dust.” It is a peculiar meta-miracle, to fuse these complementary modes of sensemaking — mathematics, the language of truth, and poetry, the language of meaning — into something that enlarges both, expanding the horizons of beauty and understanding in the mind beholding the fusion./.../

#TIME


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