Electronic cigarette (e-cigarette) use, otherwise known as “vaping,” has been increasing since 2010. This podcast reviews research on the epidemiology and possible adverse health effects of e-cigarette and nicotine use, and the pitfalls associated with using e-cigarettes as a method to stop smoking. These issues are discussed by Suchitra Krishnan-Sarin, PhD, a professor with the Department of Psychiatry at Yale University School of Medicine, and JAMA Associate Editor George O’Connor, a professor of medicine at Boston University.
This Blog AMICOR is a communication instrument of a group of friends primarily interested in health promotion, with a focus on cardiovascular diseases prevention. To contact send a message to achutti@gmail.com http://achutti.blogspot.com
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Saturday, November 30, 2019
Movies: 27 sellected from the decade
From an artistic perspective, the past decade in movies is the decade of mumblecore. The movement of intimately scaled, often improvised, low-budget dramas and comedies that pull their actors from the lives and milieux of filmmakers who build stories around their personal experiences has become the energy-giving core of the American cinema. All decade long, aside from the reliably surprising masterworks by established filmmakers such as Martin Scorsese, Clint Eastwood, Spike Lee, Sofia Coppola, Wes Anderson, Jim Jarmusch, Frederick Wiseman, and Paul Thomas Anderson, there has been a profusion of daring films by younger filmmakers who are part of the mumblecore constellation, as well as a bunch of actors (and cinematographers and other artists) who emerged from those films.
The mumblecore generation has now entered, and in many ways transformed, the true mainstream of movies: Greta Gerwig, Terence Nance, Josephine Decker, Andrew Bujalski, Amy Seimetz, Barry Jenkins, Joe Swanberg, Lena Dunham, Adam Driver, Sophia Takal, Nathan Silver, Shane Carruth, David Lowery, Kate Lyn Sheil, Alex Ross Perry, Kentucker Audley, Lynn Shelton, Robert Greene, Ronald Bronstein, and the Safdie brothers, to name just a few. I could nearly have filled my decade list with their films—but, in the interest of spreading (and acknowledging) the love, I included only a few exemplary ones./.../
US 1959-2017 Life expectancy and Mortality
JAMA
Life Expectancy and Mortality Rates in the United States, 1959-2017
Steven H. Woolf, MD, MPH; Heidi Schoomaker, MAEd
Sir Winston Leonard Spencer Churchill,
Winston Churchill
PRIME MINISTER OF UNITED KINGDOM
Alternative Title: Sir Winston Leonard Spencer Churchill
ha mais de 20 anos,(com Valderes) estivemos no Palacio onde ele nasceu. na proxima semana reuno algumas fotos e historias relacionadas
Winston Churchill, in full Sir Winston Leonard Spencer Churchill, (born November 30, 1874, Blenheim Palace, Oxfordshire, England—died January 24, 1965, London), British statesman, orator, and author who as prime minister (1940–45, 1951–55) rallied the British people during World War II and led his country from the brink of defeat to victory.
Friday, November 29, 2019
Saudade: Presence of Absence
Algumas considerações já ouvimos várias vezes (parece que há um certo orgulho de ter em nossa língua uma palavra secreta, intraduzível...).
Saudade: the untranslatable word for the presence of absence
Michael Amoruso is a visiting assistant professor at Amherst College in Massachusetts. 1,000 words Edited by Sam Dresser
I pray for friends I’ve lost, family, like my uncle who passed away,’ Bruno told me. We were chatting in the nave of the Church of the Santa Cruz of the Souls of the Hanged, a small Catholic church in central São Paulo. Built near the old city gallows, regulars go there to pray to the dead. ‘When I’m here, I feel well,’ he said. ‘I even feel that the other side is well.’ Bruno told me there was something special about the place, that it left him with a ‘sensation’. ‘The fact that you’re remembering, recalling someone that did right by you, it leaves you with even more saudade,’ he told me.
Saudade is a key emotion word for Portuguese speakers. Though akin to nostalgia or longing, the term has no direct equivalent in English. As the Brazilian musician Gilberto Gil sings in ‘Toda saudade’, it is the presence of absence, ‘of someone or some place – of something, anyway’. One can have saudades (the singular and plural forms are interchangeable) for people or places, as well as sounds, smells, and foods. One can even have saudades for saudade itself. That is because ‘it is good to have saudades’ (é bom ter saudades), as the common saying goes. There is a certain pleasure in the feeling. Though painful, the sting of saudades is a reminder of a good that came before./.../
AHA 2019
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Thursday, November 28, 2019
More on Nietzsch
The story of the camel, the lion, and the child
In 1882, Friedrich Nietzsche was a man who had known the depths of despair. Nietzsche had lived with a number of health problems, mental health issues, and post-traumatic stress syndrome from serving as a medical orderly in the Franco-Prussian War (during which he had also contracted diphtheria and dysentery). The final straw was that the woman he loved deeply, whom he had proposed to a number of times, had abandoned him.
Nietzsche was an extraordinarily gifted young man. He had studied for a PhD while still a teenager and was awarded a tenured professorship at the remarkably young age of 24.
Inequality
| Everybody knows that rich-world inequality has soared. People read about it in newspapers, hear about it from pressure groups and witness it in their daily lives. On both sides of the Atlantic politicians are building action against it into their campaigns. Yet our cover this week examines new research that suggests this growing inequality is not what it appears. Our cover story delves deep into the national account economists use to tease out the income and wealth of the top 1%, and trends in average wages and in how owners outearn workers. In each case, the growth in inequality is either smaller than most people think or, possibly, absent. That many claims made about inequality are debatable does not reduce the urgency of tackling economic injustice. The rich world’s housing markets are starving young workers of cash and opportunity. America’s economy needs a giant dose of competition. Too many high-income workers, including doctors, lawyers and bankers, are protected. But good policy starts with good data | ||
Planet resilence
| An aeroplane flies over a glacier in the Wrangell St Elias National Park in Alaska. (Frans Lanting/Nat Geo Image Collection) |
“The stability and resilience of our planet is in peril.”
Evidence is mounting that abrupt and irreversible shifts in the Earth system — such as the loss of the Amazon rainforest or the West Antarctic ice sheet — are more likely than was thought. At worst, a global cascade of these tipping points could lead to a new, less habitable, ‘hothouse’ climate state. Seven climate scientists look at the evidence for tipping points, explore the effects and urge an emergency response.
Nature | 10 min read |
Heart Inflammation
| Cells taken from bone marrow are a common stem-cell therapy. (Dennis Kunkel Microscopy/SPL) |
How stem-cell therapies mend broken hearts
Common stem-cell therapies improve heart function — but not by becoming heart-muscle cells themselves. Instead, research in mice shows that they trigger immune cells called macrophages to repair connective tissue in damaged regions of the organ. Swapping the stem cells with an inflammation-inducing chemical — or even bits of dead cells — worked, too, indicating that inflammation set off by the immune system drives the repair mechanism. The findings could have significant implications for the future of stem-cell therapies in humans, a multibillion dollar industry.
Nature | 4 min readReference: Nature paper |
Alcoholism
A dose of ketamine could lessen the lure of alcohol
The hallucinogenic drug may help treat addiction by weakening past memories of drinking
A single dose of ketamine may cut down problematic drinking. Taken in the right context, the hallucinogenic drug may be able to weaken the pull of the cues that trigger people to drink beer, researchers report November 26 in Nature Communications.
Ketamine’s influence on people’s drinking was modest. Still, the results might be a time when “small effects tell a big story,” says addiction researcher David Epstein of the National Institute on Drug Abuse in Baltimore. “If a seemingly small one-time experience in a lab produces any effects that are detectable later in real life, the data are probably pointing toward something important.”
The study hinges on the idea that addiction, in a way, is a memory disorder. People learn to associate a drug or alcohol with the good feelings it brings. Cues in the world, such as the smell or picture of a beer, can trigger those memories — and cravings. “We’re trying to break down those memories to stop that process from happening, and to stop people from relapsing,” says study coauthor Ravi Das, a psychopharmacologist at University College London./.../
black hole
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Hexavalent Chromium and Cancer
Como será que andamos por aqui? Já foi dosado nos nossos aquíferos e no |Guaíba?
Data from nearly 1,400 drinking wells across North Carolina show excessive levels of carcinogen

Some North Carolina wells contain levels of hexavalent chromium in excess of safety standards.
November 21, 2019
A new study that combines measurements from some 1,400 drinking water wells across North Carolina estimates that more than half the wells in the state's central region contain levels of cancer-causing hexavalent chromium in excess of state safety standards. The NSF-funded findings are published in Science of the Total Environment.
"Though often thought of as a byproduct of industrial contamination, hexavalent chromium can form naturally in groundwater, depending on the local aquifer geology and water chemistry," said geochemist Avner Vengosh of Duke University.
Other studies have identified naturally occurring hexavalent chromium in groundwater in Arizona, California, Argentina, Brazil, Greece, Italy and Mexico.
Only a single North Carolina well in the study violated the maximum contaminant level for total chromium set by the U.S. Environmental Protection Agency of 100 micrograms per liter. But the North Carolina Department of Health and Human Service's much lower health advisory level -- 0.07 micrograms per liter -- is set to protect against a one-in-one-million risk of cancer over a 70-year life span. That level of hexavalent chromium was exceeded by 470 of the 865 wells that were measured./.../
William Blake
William Blake
BRITISH WRITER AND ARTIST
WRITTEN BY:
LAST UPDATED: See Article History

William Blake, oil on canvas by Thomas Phillips, 1807; in the National Portrait Gallery, London.Universal History Archive/Universal Images Group/REX/Shutterstock.coTo see a World in a Grain of Sand
And a Heaven in a Wild Flower
Hold Infinity in the palm of your hand
And Eternity in an hour.
And a Heaven in a Wild Flower
Hold Infinity in the palm of your hand
And Eternity in an hour.
William Blake, (born Nov. 28, 1757, London, Eng.—died Aug. 12, 1827, London), English engraver, artist, poet, and visionary, author of exquisite lyrics in Songs of Innocence (1789) and Songs of Experience (1794) and profound and difficult “prophecies,” such as Visions of the Daughters of Albion (1793), The First Book of Urizen (1794), Milton (1804[–?11]), and Jerusalem (1804[–?20]). The dating of Blake’s texts is explained in the Researcher’s Note: Blake publication dates. These works he etched, printed, coloured, stitched, and sold, with the assistance of his devoted wife, Catherine. Among his best known lyrics today are “The Lamb,” “The Tyger,” “London,” and the “Jerusalem” lyric from Milton, which has become a kind of second national anthem in Britain. In the early 21st century, Blake was regarded as the earliest and most original of the Romantic poets, but in his lifetime he was generally neglected or (unjustly) dismissed as mad./.../
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