BP-lowering effects of aliskiren are additive to amlodipine, persist after withdrawal: ", Spain - A pooled data analysis of antihypertensive treatment with the still-investigational oral renin inhibitor aliskiren (Rasilez, Novartis) in more than 8000 patients suggest that the drug reduces blood pressure (BP) effectively regardless of age or gender, is well tolerated, and appears to be additive to most other antihypertensive agents, with the exception of angiotensin receptor blockers [1].
Dr Matthew R Weir (University of Maryland School of Medicine, Baltimore) presented the pooled analysis of results to date with this new antihypertensive agent.
'Obviously, the hope is that the mechanism of action will provide an incremental opportunity in a sense to tame the renin angiotensin system and better facilitate risk reduction with regard to cardiovascular and kidney disease progression,' he concluded. "
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