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Sunday, November 29, 2015

genetic switch for brain

Master genetic switch for brain development discovered
November 24, 2015

Figure 1: Cells in which NeuroD1 is turned on are reprogrammed to become neurons. Cell nuclei are shown in blue (Höchst stain) and neurons, with their characteristic long processes, are shown in red (stained with neuronal marker TUJ1). (credit: A. Pataskar/J. Jung & V. Tiwari) Scientists at the Institute of Molecular Biology (IMB) in Mainz, Germany have unraveled a complex regulatory mechanism that explains how a single gene, NeuroD1, can drive the formation of brain cells. The research, published in The EMBO Journal, is an important step towards a better understanding of how the brain develops and may lead to breakthroughs in … more…

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