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BARCELONA — Six months of aerobic exercise led to increased blood flow in the brain and reduced levels of phosphorylated tau protein levels in cerebrospinal fluid (CSF) in adults with mild cognitive impairment (MCI) and prediabetes.
The findings provide more evidence that aerobic exercise "holds promise as a disease-modifying therapeutic intervention" for adults in the earliest stages of Alzheimer's disease (AD), the researchers say.
Laura Baker, PhD, principal investigator and cognitive neuroscientist at Wake Forest School of Medicine, Winston-Salem, North Carolina, reported the findings at the 8th Clinical Trials Conference on Alzheimer's Disease (CTAD).