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Brain autopsies of African Americans who died with Alzheimer's disease (AD) show significantly higher rates of mixed pathologies compared with whites, suggesting more complex underlying causes of the dementia and the potential need for different therapeutic strategies, new research shows.
"Almost everything we know about Alzheimer's disease has been learned on predominantly white populations," lead author Lisa L. Barnes, PhD, from Rush University Medical Center in Chicago, Illinois, told Medscape Medical News.
"This study underscores the dangers in generalizing results from one population to another."
The findings were published online July 15 in Neurology./.../