Elderly women who take calcium supplements and had a history of stroke or white matter lesions (WMLs) may face an increased risk for dementia, a new study suggests.
Although it's too soon to make recommendations based on these new findings, clinicians may want to consider this new information in older patients who have had a stroke, said co-lead author Silke Kern, MD, PhD, Neuropsychiatric Epidemiology Unit and Clinical Neurochemistry Laboratory, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, University of Gothenburg, Sweden.
"Clinicians should assess the risks and benefits in each individual patient with cerebrovascular disease," Dr Kern.
The findings are published online August 17 in Neurology.
The study, a sample derived from the Prospective Population Study of Women and H70 Birth Cohort in Gothenburg, Sweden, included 700 women, 98 of whom were treated with calcium supplementation. There were no differences between the women who took these supplements and those who didn't in terms of baseline age, Mini-Mental State Examination (MMSE) score, education, and most health factors.
During a period of 5 years (2000 to 2005), 59 women developed dementia.