3.169 - AMICOR (26)

 3.169 - AMICOR (26) Última postagem de 2.023. Desejando a todos os AMICOR e visitantes mais um ano com Saúde e Felicidade, enquanto pretendemos completar 27 anos encontrando-nos pela INTERNET. Um abraço a todos e agradecimentos pela companhia. Aloyzio

#com Dra. Valderês A. Robinson Achutti (*13/06/1931+15/06/2021)

Visitando uma feira por aqui mesmo...

#Re-Publicando artigos meus, mais antigos.
O Relógio da Vida.   (26/12/2000)

Aloyzio Achutti. 

Dia-ano-século-milênio, e o compasso do tempo se perpetua, acionado pela mola da memória

e da imaginação, na medida em que o presente, em busca do futuro, vai se arquivando no passado.

O dia e o ano têm um ritmo natural, evidente no ciclo diuturno e no sazonal. Os outros  entretanto, século e milênio, têm muito de convenção, mas não deixam de ter seu significado no contexto da história, porque embora não sejam marcados pelo relógio cósmico, no biológico,  guardam o tique-taque da vida umana, e as badaladas de seus eventos mais marcantes.

Em geral, nas muitas cronologias publicadas nesta época, o interesse recai nos grandes sucessos, nas descobertas maravilhosas, nos desastres, nas guerras, e em seus personagens mais famosos. Ao rever o espetáculo, com a atenção  para as grandes datas, para as horas cheias, para eventos marcantes, e os super-heróis, perde-se o pulsar quase imperceptível dos minutos e segundos, de componentes menores,  de pessoas comuns, não desprezíveis, nos quais a vida e a história se realizam.

Essa alegoria tem me levado a pensar na valorização  do espetacular, fazendo sombra ao dia a dia, e no culto aos super-heróis, em detrimento das pessoas comuns (em última análise, da pessoa humana como tal). Esta pode ser uma característica de nosso tempo, que se não for peculiaridade dele, nele tem se manifestado, contando com instrumentos muito eficazes. Se o individualismo abriu o caminho para a concentração de riquezas, marginalizando multidões, como o pêndulo de um grande relógio, o coletivismo exagerou para o lado oposto, mas com idêntica repercussão sobre a pessoa, concentrou o poder em alguns poucos líderes, enquanto criava uma expressão borrada e homogeneizada do conjunto da humanidade. 

A sabedoria da vida está na biodiversidade, que ao se dispersar se auto-regula, se ordena e se reproduz, preservando a identidade de cada um de seus elementos fundamentais com aquilo que lhe é próprio. O grande engano vem da padronização, do estereótipo, da formatação que, se bom para a produção industrial e para aumentar eficiência de qualquer processo, ou para tentar controlar  comportamento, é incompatível com a vida, dentro de sua complexidade e da individualidade de cada ser. Na imaginação do demagogo e do burocrata é tentador trabalhar com a fantasia e retirar a densidade de cada indivíduo, sua identidade, transformando-o num elemento numérico e virtual. Fomos capazes de desenvolver recursos maravilhosos que nos abstraíram da realidade, insuflando a imaginação: a reprodução e a transmissão  cada vez mais perfeita do som e da imagem, a divulgação maciça de idéias, e a estimulação de sentimentos. A modelagem estatística, a terceira dimensão, a  holografia, o mundo cibernético, a inteligência artificial nos arrebatam. Tentam-nos as panaceias, as receitas universais, o aconselhamento em massa, a falácia da medicina sem a relação personalizada médico-paciente. Entretanto, continuarão resistindo os indivíduos, com suas características próprias, com o pulsar elementar e inconfundível de suas vidas.

É curioso que neste final de século tenha se propagado tanto uma epidemia (AIDS) que destrói o sistema imunitário, responsável também, no terreno biológico, pela identificação do que é próprio e não próprio a cada organismo, expondo-o à invasão oportunística. Também aprendemos na medicina a inibir o mesmo sistema com finalidade terapêutica, para prolongar a vida e, ludibriando a identidade, transplantar órgãos de uns para os outros. A clonagem,  também tem tentado fazer indivíduos pretensamente idênticos,  no caminho oposto ao da natureza.

A quebra dos códigos que garantem a biodiversidade, tido como dos maiores feitos científicos de 2.000,  dá-nos uma ilusão de poder de vida e de morte, de recuperação da saúde e de destruição do equilíbrio vital sobre esta terra. A natureza, no entanto, se reserva um último truque ao disponibilizar a vida não como um produto acabado, moldado definitivamente pelos padrões genéticos, mas como algo que se sustenta no tempo, se renova e se adapta na fugacidade de cada instante, neste enorme relógio que vai diferenciando cada indivíduo do outro, não permitindo a perda da identidade de cada um, e ao mesmo tempo, nos mantém inexoravelmente, grandes e pequenos, famosos e humildes, todos solidários num único e mesmo contexto.

#Núcleo de Reanimação Cárdio-Respiratória
do Hospital de Clínicas - Departamento de Pediatria

Com grande satisfação recebi notícias do Núcleo de Reanimação CR, coordenado com sucesso pela Professora Tais Sica da Rocha desde o passamento da   Professora Eliana Trotta. Essa atividade que antes inexistia no currículo da Faculdade de Medicina criei no fim da década de 80, na Disciplina de Promoção e Proteção da Saúde III (Med 114) sob minha regência. Foi muito importante o interesse e o apoio de três acadêmicos de então - hoje eminentes profissionais - Eduardo Estrella, Sandro Gonçalves e Stephen Stefani.

Diz a diretora atual que desde 2014 já treinaram 8.919 novos socorristas: TODOS PODEM SALVAR-VIDAS! SEJA UM SOCORRISTA!

UTI pediátrica Diretora do Programa de ECMO do Hospital de Clínicas de Porto Alegre

Coordenadora do Núcleo de Treinamento em Reanimação Cardiorrespiratória

Departamento de Pediatria/ Faculdade de Medicina/UFRGS  3359-8399 ou 33598374

#

Our Top 5 Videos of 2023

VIDEO | ALL TOPICS   How AI Discovered a Faster Matrix Multiplication Algorithm DeepMind researchers trained an AI system called AlphaTensor to find new, faster algorithms for matrix multiplication. AlphaTensor quickly rediscovered — and surpassed, for some cases — the reigning algorithm discovered by German mathematician Volker Strassen in 1969. Watch the video | Read the article Can a New Law of Physics Explain a Black Hole Paradox? A group of physicists recently used circuit complexity, a concept from computer science, to describe the quantum evolution of physical systems. Some computer scientists who initially balked at the idea have since become its closest allies. Watch the video | Read the article Could One Physics Theory Unlock the Mysteries of the Brain? Some neuroscientists hypothesize that our brains work optimally at a “critical point” between subcritical and supercritical extremes. If so, brain diseases like epilepsy could be associated with a divergence from the critical point. Watch the video | Read the column When Computers Write Proofs, What’s the Point of Mathematicians? What is a mathematical proof? What we tend to think of as an eternal, immutable truth, is perhaps better understood as a social construct, number theorist Andrew Granville explains. Watch the video | Read the interview P vs. NP: The Greatest Unsolved Problem in Computer Science How hard is it to prove that a problem is hard? This question is at the heart of meta-complexity, an area of theoretical computer science with implications that go far beyond any specific technology. Watch the video | Read the article

NEUROSCIENCE | ALL TOPICS   The Cause of Depression Is Probably Not What You Think By JOANNA THOMPSON Depression has often been blamed on low levels of serotonin in the brain. That answer is insufficient, but alternative explanations are coming into view and changing our understanding of the disease. Read the article

NEUROSCIENCE   How Loneliness Reshapes the Human Brain By MARTA ZARASKA Feelings of loneliness prompt changes in the brain that further isolate people from social contact. Read the article QUANTIZED COLUMNS   When Does the Brain Operate at Peak Performance? By JOHN M. BEGGS The critical brain hypothesis suggests that neural networks do their best work when connections are not too weak or too strong. Read the article | Watch the video GENOMICS   How a DNA ‘Parasite’ May Have Fragmented Our Genes By JAKE BUEHLER A novel type of “jumping gene” may explain why the genomes of some complex cells are more densely stuffed with noncoding sequences than others. Read the article PHYSIOLOGY   In the Gut’s ‘Second Brain,’ Key Agents of Health Emerge By YASEMIN SAPLAKOGLU Sitting alongside the neurons in your enteric nervous system are underappreciated glial cells, which play key roles that scientists are only just starting to understand. Read the article

ARTIFICIAL INTELLIGENCE | ALL TOPICS   The Unpredictable Abilities Emerging From Large AI Models By STEPHEN ORNES Large language models like ChatGPT are now big enough that they’ve started to display startling, unpredictable behaviors. Read the article

MACHINE LEARNING   A New Approach to Computation Reimagines Artificial Intelligence By ANIL ANANTHASWAMY By imbuing enormous vectors with semantic meaning, we can get machines to reason more abstractly and efficiently than before. Read the article COMPUTATIONAL COMPLEXITY   Complexity Theory’s 50-Year Journey to the Limits of Knowledge By BEN BRUBAKER How hard is it to prove that problems are hard to solve? A string of recent results has started to deliver answers. Read the article   NEURAL NETWORKS   Researchers Discover a More Flexible Approach to Machine Learning By STEVE NADIS “Liquid” neural nets, based on a worm’s nervous system, can transform their underlying algorithms on the fly, giving them unprecedented speed and adaptability. Read the blog   ALGORITHMS   The Most Important Machine That Was Never Built By SHEON HAN At 23 years old, Alan Turing helped define computation, algorithms and what came to be known as Turing machines — the foundation for modern computing. Read the blog

QUANTUM PHYSICS | ALL TOPICS   Physicists Use Quantum Mechanics to Pull Energy out of Nothing By CHARLIE WOOD The quantum energy teleportation protocol was proposed in 2008 and largely ignored. Now two independent experiments have shown that it works. Read the article

EXPLAINERS   How Our Reality May Be a Sum of All Possible Realities By CHARLIE WOOD Richard Feynman’s path integral is both a powerful prediction machine and a philosophy about how the world is. But physicists are still struggling to figure out how to use it, and what it means. Read the article MATHEMATICAL PHYSICS   A New Kind of Symmetry Shakes Up Physics By KEVIN HARTNETT Symmetry has been a crucial ingredient in every major advance in physics for more than a century. In recent years, symmetries have been reformulated into a form that can now be applied to quantum field theory, promising new breakthroughs. Read the article ASTRONOMY   Astronomers Say They Have Spotted the Universe’s First Stars By JONATHAN O'CALLAGHAN Theory has it that “Population III” stars brought light to the cosmos. The James Webb Space Telescope may have just glimpsed them. Read the article THEORETICAL PHYSICS   ‘Alien Calculus’ Could Save Particle Physics From Infinities By CHARLIE WOOD Feynman diagrams brought a measure of meaning to the infinities of quantum electrodynamics. But deep down, this way of approaching quantum field theory doesn’t really work at all. Read the article

NUMBER THEORY | ALL TOPICS   Two Students Unravel a Widely Believed Math Conjecture By MAX G. LEVY Mathematicians thought they were on the cusp of proving a conjecture about the ancient structures known as Apollonian circles. But a summer project would lead to its downfall. Read the article

COMBINATORICS   Surprise Computer Science Proof Stuns Mathematicians By LEILA SLOMAN Two computer scientists have found a new, dramatically lower limit to the maximum size of a set of integers in which no three of them are evenly spaced. Read the article NUMBER THEORY   Behold Modular Forms, the ‘Fifth Fundamental Operation’ of Math By JORDANA CEPELEWICZ Modular forms are one of the most beautiful and mysterious categories of objects known to mathematicians. But what exactly are they? Read the explainer   TOPOLOGY   An Old Conjecture Falls, Making Spheres a Lot More Complicated By KEVIN HARTNETT The telescope conjecture gave mathematicians a handle on ways to map one sphere to another. Now that the conjecture has been disproved, the universe of shapes has exploded. Read the article COMBINATORICS   Mathematicians Find Hidden Structure in a Common Type of Space. By JORDANA CEPELEWICZ In 50 years of searching, mathematicians found only one example of a “subspace design” that fit their criteria. A new proof reveals that there are infinitely more examples out there. Read the article

#UNDP 

In 2023, we delivered five flagship initiatives and dedicated ourselves to the upcoming HDR, which explores the current gridlock of slow collective action on key global challenges, exacerbated by a lack of trust and polarization, and proposes ways to address it.”  HDRO has spearheaded thought leadership through cutting-edge knowledge products, impactful publications, statistical and digital platform innovations, and new knowledge networks. Produced and launched 5 flagship initiatives 2023 Gender Social Norms Index Report Gender bias is a pervasive problem worldwide. The Gender Social Norms Index (GSNI) quantifies biases against women, capturing people’s attitudes on women’s roles along four key dimensions: political, educational, economic and physical integrity. The index, covering 85 percent of the global population, reveals that close to 9 out of 10 men and women hold fundamental biases against women. Read more here Human Climate Horizons data and insights platform In the latest release, Human Climate Horizons data and insights platform (HCH) unveils projections of sea level rise and its impacts on people and land in over 5,000 coastal regions and major cities worldwide. Read more here The paths to equal With data for 114 countries, the report introduced a new multidimensional framework to measure the status of women’s empowerment and gender equality across the world, with the Women’s Empowerment Index (WEI) and the Global Gender Parity Index (GGPI) as new twin indices. Read more here 2023 Multidimensional Poverty Index Report (MPI) The Corporate Human Development Community Of Practice In addition, HDRO has supported the development of National and Regional HDRs, and has co-led the next generation of NHDR’s strategy in collaboration with regional bureaus and human development experts across the organization and beyond. HDRO has actively broadened partnerships and collaborations, fostering meaningful relationships with key institutions and organizations at both global and local levels. Engaged with over 40 institutions at all levels, including international organizations, universities, research networks, think tanks, private sector actors, governments, and others. PRIO, IIASA, Harvard University, the German Development Institute, HDCA, CUNY, the Migration Policy Institute, OPHI, the Stockholm Institute, the University of Bristol, the University of Maryland, the LR Foundation, Planet, PRRM, OECD Save the Children, UNICEF, UNITAR, UNV, and many others. Additionally, HDRO has participated in over 100 group or bilateral discussions with key experts and stakeholders. HDRO has convened key experts and stakeholders in events and consultations that drove thought leadership and innovation. Organized over 20 thematic and regional consultations and other events, with over 500 participants 2023 HDR Thematic Consultation: International Institutions in Radically Uncertain Times organized in collaboration with the Oxford Martin Programme on Changing Global Orders. The consultation brought together a multidisciplinary group of prominent historians, economists, sociologists, biologists, and political scientists. 2023 HDR Regional Consultation: Arab States jointly organized with UNDP RBAS, the consultation focused on government mismatches and the need for collective action. The consultation brought together prominent experts, academics, and practitioners from the region and senior managers and specialists from UNDP. 2023 & 2024 HDR Thematic Consultation: Our Shared Digital Future organized in collaboration with the Craig Newmark Center for Journalism Ethics and Security. It brought together prominent scholars and practitioners from the fields of political science, journalism, technology studies, law, philosophy, and biology. 2023 HDR Thematic Consultation: South-South Cooperation partnered with the United Nations Office for South-South Cooperation (UNOSSC) and South-South Global Thinkers, a joint initiative by UNOSSC and UNDP, the technical consultation draw perspectives from the Global South, and brought together prominent experts, scholars, and practitioners in the field, along with senior managers and specialists from UNDP and UNOSSC. 2023 HDR Regional Consultation: Latin America and the Caribbean organized with UNDP RBLAC, the consultation addressed the topics of governance mismatches and investing in one another in the region of Latin America and the Caribbean. Prominent specialists, scholars, and practitioners in the region were involved in the discussion, together with senior managers and specialists from UNDP. Signals of change shaping the landscape around collective action organized with the UNDP’s Strategy & Futures Team drew on UNDP’s global Futures Network to identify signals of change shaping the landscape around collective action - both enablers and obstacles, including interesting examples of collective action itself at community, country or international level. For other events please click here HDRO-produced knowledge has had a significant digital reach, and was referenced and utilized in the formulation of policy documents at both global and local levels, including policy briefs by the SG in preparation for the SDG Summit and the upcoming Summit of the Future, and the midterm review of the implementation of the Sendai Framework for Disaster Risk Reduction, and many others. HDRO’s knowledge products have received widespread media coverage, strengthening both the brand and global recognition. Publications, knowledge products, and events have had broad media coverage, often from the top tier global news outlets. The Human Development Reports achieved an impressive average of over 3 billion monthly Unique Visitors (UVM), representing the combined potential reach of the news outlets with thousands of monthly media links, while the Human Development Index (HDI) had average monthly UVM of over 10 billion.

#MEDSCAPE

Toxic Chemicals We Consume Without Knowing It

Akash Goel, MD

DISCLOSURES 

February 23, 2023

54

837

If the pandemic served as a window into our health, what it revealed was a US population that is not only sick but also seemingly only getting sicker. Life expectancy is falling precipitously. Three fourths of Americans are overweight or obese, half have diabetes or prediabetes, and a majority are metabolically unhealthy. Furthermore, the rates of allergic, inflammatory, and autoimmune diseases are rising at rates of 3%-9% per year in the West, far faster than the speed of genetic change in this population.

Of course, diet and lifestyle are major factors behind such trends, but a grossly underappreciated driver in what ails us is the role of environmental toxins and endocrine-disrupting chemicals. In years past, these factors have largely evaded the traditional Western medical establishment; however, mounting evidence now supports their significance in fertility, metabolic health, and cancer.

Although several industrial chemicals and toxins have been identified as carcinogens and have subsequently been regulated, many more remain persistent in the environment and continue to be freely used. It is therefore incumbent upon both the general public and clinicians to be knowledgeable about these exposures. Here, we review some of the most common exposures and the substantial health risks associated with them, along with some general guidance around best practices for how to minimize exposure.

#Hospital Moinhos de Vento - O Tempo

#Marginalia, Maria Popova

FROM THE ARCHIVE | Resolutions for a Life Worth Living: Attainable Aspirations Inspired by Great Humans of the Past

If we abide by the common definition of philosophy as the love of wisdom, and if Montaigne was right that philosophy is the art of learning to die, then living wisely is the art of learning how you will wish to have lived. A kind of resolution in reverse.

This is where the wisdom of lives that have already been lived can be of immense aid — a source of forward-facing resolutions, borrowed from people who have long died, having lived, by any reasonable standard, honorable and generous lives, lives of beauty and substance, irradiated by ideas that have endured across the epochs to make other lives more livable.

Here are ten such ideas (after many more highlighted in years past) that make for life-expanding resolutions, and an extra eleventh as an overarching ethos./.../