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Monday, April 21, 2025

3.196 AMICOR

  3.196 - AMICOR

# Entrega de Ficha Clínica

Hoje tive a grata satisfação de receber a visita de um amigo, ex-cliente, primeira consulta em 26/06/1972. Na foto eu lhe entregava documentos de sua ficha, que para mim expressam minha decisão de dar por encerrada minha atividade clínica. Dra. Valderês, falecida em 2021, dez anos antes, por problemas de saúde, já não tinha mais condições de me acompanhar.

Lembrei-me que mais ex-clientes ou seus familiares poderão querer ficar com registros semelhantes, e que no futuro terão que ser incinerados. Fiquem a vontade de contactar comigo, e eu terei o prazer de lhes entregar o que lhes pertence.

# Outorga do Título de Professor Emérito da UFRGS

Ao Amigo e Professor Doutor Gilberto Schwartsmann, assisti na manhã do dia 17/04/2025, na sala do Conselho na Reitoria da UFRGS. Tive oportunidade de cumprimenta-lo, bem como a sua Exma. Esposa, Dra. Leonor. A cerimônia e os pronunciamentos, foram gravados e devem estar acessíveis no site da Universidade


# ACADEMIA SR DE MEDICINA Sessão Cultural

Link de acesso:

https://meet.google.com/hhf-oada-eqp?authuser=6&pli=1

ID: hhf oada eqp

# No dia 14, na reabertura do MUSEU da História da Medicina,
com a Presidente da Academia SRM

PERCEPTION | ALL TOPICS

 

Touch, Our Most Complex Sense, Is a Landscape of Cellular Sensors

By ARIEL BLEICHER

Every soft caress of wind, searing burn and seismic rumble is detected by our skin’s tangle of touch sensors. David Ginty has spent his career cataloging the neurons beneath everyday sensations.

Read the article

GRAPH THEORY

 

New Proof Settles Decades-Old Bet About Connected Networks

By LEILA SLOMAN

According to mathematical legend, Peter Sarnak and Noga Alon made a bet about optimal graphs in the late 1980s. They’ve now both been proved wrong.

Read the article

ARTIFICIAL INTELLIGENCE

 

To Make Language Models Work Better, Researchers Sidestep Language

By ANIL ANANTHASWAMY

We insist that large language models repeatedly translate their mathematical processes into words. There may be a better way.

Read the article


THE JOY OF WHY

 

Can Quantum Gravity Be Created in the Lab?
With STEVEN STROGATZ and JANNA LEVIN

Monika Schleier-Smith discusses her pioneering experimental approach, which uses laser-cooled atoms to explore whether gravity could emerge from quantum entanglement.

Listen (Apple) | Listen (Spotify)

Read the transcript



Each week Quanta Magazine explains one of the most important ideas driving modern research. This week, math staff writer Joseph Howlett explores the deep math behind simple lists of numbers.

 

The Simple Beauty of Number Sequences

By JOSEPH HOWLETT

We encounter our first mathematical pattern when we learn how to count: 1, 2, 3, 4, 5 and so on. This is just one example of a sequence, a list of numbers arranged in a particular order. It’s also one of the most fundamental, bare-bones objects in math. If you think you have zero mathematical intuition, just look at the sequence 1, 3, 5, 7, and you can likely guess what comes next. The accessibility of these kinds of questions has drawn in recreational mathematicians for decades or longer.
 
But despite their simplicity, sequences also encode deep mathematical relationships. By probing sequences, mathematicians have made surprising discoveries that have greatly influenced the history of the field.
 
The twin motivations of pure research and pure fun collide beautifully in the On-Line Encyclopedia of Integer Sequences (OEIS), a database of sequences created by Neil Sloane in 1964. (Erica Klarreich profiled Sloane for Quanta in 2015.) The OEIS is a trove of whimsical oddities that mathematicians have come across while toying with numbers in their free time. But it also contains some of the oldest and most important objects in math.
 
Today, lists of numbers continue to intrigue and flummox number theorists, while offering new insights into problems all over mathematics. Let’s take a look at a few of them and see what makes them so interesting.
 
Sequence of Events
 
Consider the sequence formed when you take every whole number, square it, and add 1. You get 2, 5, 10, 17 and so on. Though straightforwardly defined, the n2 + 1 sequence (A002522 in the OEIS) is actually very difficult to study, because it combines multiplication (squaring a number) with addition (adding 1). Both operations are simple enough on their own, but when combined, they lead to deep mathematical questions. In fact, the strange relationship between addition and multiplication forms one of the biggest tensions in number theory — and the n2 + 1 sequence provides a perfect entry point for studying it. Last year, Quanta reported on the latest advance in understanding the sequence: The mathematician Hector Pasten proved that all of its numbers have a relatively large prime factor. The work also marked the first progress in a while on a particularly famous problem about addition and multiplication, one rife with drama — the abc conjecture.
 
Other kinds of sequences are inspired by nature. Take the Fibonacci sequence (A000045), which is what mathematicians call recursive: You can always calculate the next number using those that come before it. In this case, each number is the sum of the two preceding numbers in the list, so that you get 0, 1, 1, 2, 3, 5, 8, etc. This sequence, which was first described in Indian poetry dating back millennia, appears all over nature — in the arrangement of a pine cone, in the syllables of human speech, in the population dynamics of certain species.
 
This sequence is also known to pop up unexpectedly all over math. In 2022, for instance, mathematicians found the Fibonacci numbers hidden in a host of geometric structures. The following year, another team proved that the solutions to a famous equation are related to each other in part through the Fibonacci sequence (as well as through another ancient, recursive list of numbers, called the Pell sequence [A000129]). New discoveries about the Fibonacci numbers continue to pile up on a weekly basis.
 
Another kind of sequence that shows up all over math: lists of evenly spaced numbers called arithmetic progressions. For example, the sequence 2, 5, 8, 11, 14, etc. (A016789), is an arithmetic progression whose numbers all differ by 3. Quanta has covered several results in which mathematicians study how arithmetic progressions inevitably appear in random sets of numbers. In this way, sequences are a great way to explore how, no matter how hard you try, you can’t avoid the emergence of mathematical order.
 
But the most important sequence for research mathematicians is the one formed by the prime numbers (A000040), the building blocks of all other numbers. It’s still a mystery what numbers even belong to this sequence: As the number line stretches to infinity, it becomes harder and harder to pinpoint where the primes are located. Check out this earlier edition of Fundamentals to learn more about prime numbers.
 
These are just a few of the many sequences that mathematicians enjoy studying. Researchers will likely never run out of simple but hard-to-answer questions concerning ordered lists of numbers. In this way, sequences will continue to be a source of crucial discoveries — and entertainment, as evidenced by the OEIS’s enduring popularity more than half a century after its creation.

AROUND THE WEB

One important compendium of new discoveries in sequence science is The Fibonacci Quarterly. You can read articles and papers going all the way back to the publication’s first issue in 1963 (including one submitted by a high school student).
 
Prime numbers that are one less than a power of 2 form a sequence called the Mersenne primes. By studying this sequence through the Great Internet Mersenne Prime Search (GIMPS), a researcher and amateur mathematician named Luke Durant was able to discover the largest known prime: 2136,279,841 − 1. The GIMPS website has a nice explanation of why someone would spend their time this way.

My favorite silly sequence is the comma sequence (A121805), in which the positions of the commas separating numbers are actually involved in calculating which numbers are part of the sequence. Last year, two Rutgers mathematicians proved that this sequence is finite no matter which base you write your numbers in. (In base 10, the sequence is 2,137,453 numbers long, ending abruptly at 99,999,945.) The sequence’s discoverer, Éric Angelini, told me by email, “I am not a mathematician, just an amateur with ideas but no skills at all.” I recommend this YouTube video made by Angelini’s son to commemorate his birthday.

The OEIS lets you listen to any sequence rendered as music. Here's a link to the page for the comma sequence (just change the sequence number in the URL to hear a different one) and a link to the audio. It suddenly does a really cool thing starting at 1:03.

# Dra. Gláucia Moraes de Oliveira
Me enviou, a propósito do falecimento do Papa Francisco, copia de cartaz que ela ajudou a colocar no Congresso Europeu de Cardiologia de 2016...
# Visita de colega, presente de Páscoa...

Tuesday, April 15, 2025

3.195 - AMICOR

  3.195 AMICOR

# UFRGS

UFRGS mantém-se como a melhor universidade federal brasileira

Universidade registrou crescimento no IGC Contínuo pelo quinto ano consecutivo. Resultados dos Indicadores de Qualidade da Educação Superior de 2023 foram divulgados nesta sexta-feira, 11/04, pelo Inep.

O Instituto Nacional de Estudos e Pesquisas Educacionais Anísio Teixeira (Inep) divulgou na tarde desta sexta-feira, 11, os resultados dos Indicadores de Qualidade da Educação Superior 2023, que abrangem dados do Conceito Enade, do Indicador de Diferença entre os Desempenhos Observado e Esperado (IDD), do Conceito Preliminar de Curso (CPC) e do Índice Geral de Cursos Avaliados da Instituição (IGC) de 2023. A UFRGS obteve novamente o conceito 5 (nota máxima) no Índice Geral de Cursos, e 4,523 no IGC Contínuo, mantendo-se como melhor universidade federal do País e segunda melhor entre todas as instituições avaliadas. A primeira colocada é a Unicamp (instituição estadual de SP), que obteve IGC Contínuo de 4,64.



















     Conforme pode ser visto na notícia da AAMUHM, a esposa do Prof. Gilberto, Dra. Leonor Schwartsmann, também foi homenageada

#IHME


# LIVE SCIENCE

This Mysterious Cosmic Substance May Be Older Than the Universe Itself—And It Just Might Be Immortal

It drives the movements of stars and galaxies, but dark matter is invisible. While it remains a colossal mystery, a study revealed how staggering its age could be. By 


A mysterious substance rules the present-day universe. New research suggests that it may have been born even before our cosmos as we know it, and that if it does eventually leave the cosmic scene, it won’t be for another trillion trillion years…if ever. 
Welcome to the kingdom of the dark.

Consciousness Isn’t Just in Your Head—It May Be Altering Reality Itself, Scientists Say By  

What if your mind is shaping the world around you in ways you can’t see ... or even imagine?

Ever since we published our very first issue 123 years ago—yes, we’re old—Popular Mechanics has endeavored to help you understand all kinds of technological marvels, from the tools in your shed, to the planes in the sky, to the tanks on the battlefield. But lately, we’ve really tried to dive deep into the world’s most complex machine: you.
Or, more specifically, the thing that makes you youconsciousness.

#  TIME

The Return of the Dire Wolf  Photographs by Robert Clark Story by Jeffrey Kluger

Romulus and Remus are doing what puppies do: chasing, tussling, nipping, nuzzling. But there’s something very un-puppylike about the snowy white 6-month olds—their size, for starters. At their young age they already measure nearly 4 ft. long, tip the scales at 80 lb., and could grow to 6 ft. and 150 lb. Then there’s their behavior: the angelic exuberance puppies exhibit in the presence of humans—trotting up for hugs, belly rubs, kisses—is completely absent. They keep their distance, retreating if a person approaches. Even one of the handlers who raised them from birth can get only so close before Romulus and Remus flinch and retreat. This isn’t domestic canine behavior, this is wild lupine behavior: the pups are wolves. Not only that, they’re dire wolves—which means they have cause to be lonely./.../

#

World’s Most Detailed Map Built From a Grain of Brain Tissue

This image shows a subset of more than 1,000 of the 120,000 brain cells (neuron + glia) reconstructed in the MICRONS project. Each reconstructed neuron is a different random color. In this image, the glowing neurons are colored. Credit: Forrest Collman/Allen Institute

Summary: Scientists have created the most detailed wiring diagram of a mammalian brain to date, mapping every cell and synapse in a cubic millimeter of a mouse’s visual cortex. Using cutting-edge microscopy, AI, and 3D reconstruction, researchers captured more than 200,000 cells and over 500 million connections.

The work revealed surprising principles of brain organization, including new inhibitory cell behaviors and network-wide coordination. This achievement provides a foundational tool for understanding brain function, intelligence, and neurological disorders.

# MARIA POPOVA -  The Marginalia

How Two Souls Can Interact with One Another: Simone de Beauvoir on Love and Friendship

It is in relationships that we discover both our depths and our limits, there that we anneal ourselves and transcend ourselves, there that we are hurt the most and there that we find the most healing.

But despite what a crucible of our emotional and spiritual lives relationships are — or perhaps precisely because of it — they can be riddling and nebulous, destabilizing in their fluidity and ambiguity, leaving us grasping for the comforting solidity of categories and labels. The ancient Greeks, in their pioneering effort to order the chaos of the cosmos, neatly taxonomized them into filial love (the kind we feel for siblings, children, parents, and friends), eros (the love of lovers), and agape (the deepest, purest, most impersonal and spiritual love). After the Enlightenment discounted all love as a malfunction of reason, the Romantics reclaimed it and revised the ancient taxonomy into a hierarchy, under the tyranny of which we still live, placing eros at the pinnacle of human existence. And yet our deepest relationships — the ones in which we both become most fully ourselves and are most emboldened to change — tend to elude the commonplace classifications and to shape-shift across the span of life./.../

#MUHM Na primeira versão da homenagem às Mulheres na área da Saúde Dra. Valderês Robinson Achutti foi uma das representantes

Presente, estavam também, a Presidente da Academia SR de Medicina  Professora Miriam da Costa Oliveira e a Dra. Leonor Schwartsmann, uma das homenageadas. Assisti juntamente com minha irmã 
Dra. Maria Helena Cechella Achutti.

# CHC Santa Casa
Desejo desde já uma Feliz Páscoa a todos os AMICOR, se eu não conseguir editar 3.196

Saturday, March 29, 2025

3.194 - AMICOR

 AMICOR 3.194

#TVE                primeira a esquerda ! fila de cima


PANDORGA ESPECIAL - EPISÓDIO INÉDITO

Pandorga está de volta para encerrar as comemorações dos 50 anos da TVE

No sábado, 29 de março, a TVE fecha o ciclo do cinquentenário e comemora 51 anos de televisão pública no Rio Grande do Sul com a exibição de um Pandorga inédito, às 10h45 da manhã. A turma de bonecos formada por Nina, Beti, Jura, Tinta, Zé Cão e tantos outros fará parte das atrações de um Jornal Legal “muito especial”, que contará com auditório, matérias e entrevistas inéditas, além da reprise de quadros do programa Pandorga. Tudo sob o comando dos apresentadores “Anete E-mail” – a pedagoga e atriz Maria Inês Falcão, idealizadora do programa – e “Carlos@” – o ator Oscar Simch, que integrou o grupo do Pandorga a partir dos anos 1990.

O programa será comentado, diretamente de uma arquibancada, por produtores, atores e bonequeiros que participaram de diferentes fases do Pandorga: Iara de Almeida, João Brites, Joice de Brito e Cunha, Laura Medina, Lúcia Achutti, Maria Lúcia Melão, Mario de Ballentti e Vera Vergo. Além disso, haverá uma edição inédita do Diário da Nina, em que a boneca conta sobre sua visita à Terreira da Tribo de Atuadores Ói Nóis Aqui Traveiz, e uma matéria do Tinta Repórter, que conversa com alunos do Colégio Santa Cecília sobre a retirada dos celulares da sala de aula neste ano.

Criado em 1988 e exibido em temporadas até 2015, o Pandorga marcou pelo menos duas gerações de crianças, não apenas gaúchas, pois foi transmitido na programação da TV Brasil e exibido em diversos países. Com uma linguagem bem regional, abordava temas do cotidiano das crianças do Rio Grande do Sul, como educação e leitura, ecologia, brincadeiras e questões de consumo. O programa inovou ao utilizar técnicas de manipulação direta e cenários em miniatura, conquistando prêmios como o Açorianos de Literatura e o da Associação Gaúcha de Teatro de Bonecos. Tudo isso embalado pela canção “Papagaio, Pandorga”, de Gelson Oliveira.

Herpes Virus Linked to Long-Term Brain and Neurological Problems

Summary: A new study reveals that herpes simplex virus-1 (HSV-1), commonly known for causing cold sores, can travel through the nasal cavity directly to the brain, causing severe and lasting neurological symptoms. In animal experiments, nasal HSV-1 infection led to persistent neurological dysfunction, including anxiety and cognitive impairment.

The researchers identified heparanase, a cellular enzyme, as a critical factor in allowing HSV-1 to cause severe, lasting neurological damage. Blocking the activity of this enzyme significantly reduced neurological damage in infected animals, highlighting a possible therapeutic target.

#


 Essential India

Essential India helps you understand a vast and complicated country that will increasingly shape the future. India has the world’s biggest population and in recent years has had one of its fastest-growing economies with a large and thriving business and tech scene. It is the world’s biggest democracy, an almost miraculous achievement for such a poor and diverse country—even if its politics has grown increasingly authoritarian under Narendra Modi. India is emerging as an important player on the geopolitical stage, in hock neither to China nor America, and as a self-styled leader of the global south. Each week our correspondents will share their insights on the big Indian news and business developments, keeping you in the loop with everything from cricket to technology, social trends and electoral politics.

# MAGNETISM

 · 
Follow

Good question! I tried to work this out from the ripe age of 17, but it took me until my fourth year of undergraduate until I understood it fully. Here is the more 'technical' answer on where it comes from and why James Clerk Maxwell managed to unify it with the electric force:

One way to think about magnetism is that it is the 'relativistic correction' to the electrostatic force. This is because all information (including the spread/continual update of electric fields as charges move) can not travel faster than the speed of light.
Thus, only 
moving charge particles feel a magnetic force in a m

… (more)

# UNIVERSIDADE DE PORTO ALEGRE - FUNDAÇÃO - 1934



#

L'indice planète vivante (IPV, en anglais living planet index ou LPI) est un indicateur d'état de la biodiversité, utilisé pour l'évaluation environnementale, en particulier par l'ONU.

Selon le Rapport planète vivante 2022 de WWF, l'indice planète vivante affiche un déclin de 69 % des populations mondiales de vertébrés entre 1970 et 2018.

C'est un indice composite1 construit sur les tendances observées chez un grand nombre de populations d'espèces de vertébrés du monde entier (les vertébrés sont parmi les mieux connus des taxons animaux2) ; il vise à mesurer les changements temporels d'état de la biodiversité dans le monde3. Il consiste dans la moyenne des taux de décroissance de la population de nombreuses espèces de vertébrés témoin, par rapport à celle de l'année 1970.

Neuroscience News Logo

Exercise Boosts Memory Across All Ages

Summary: New research finds that nearly any form of exercise can enhance brain function and memory across the lifespan. This large-scale umbrella review analyzed data from over 258,000 participants and found that low- to moderate-intensity activities like yoga, Tai Chi, and even exergames significantly benefit cognition.

Children and teens saw the greatest memory gains, while people with ADHD experienced notable improvements in executive function. The findings highlight that even small bursts of movement can have profound cognitive effects, making exercise an accessible and essential brain-health strategy for everyone./.../

#Hospital Moinhos de Vento

# BBC
The Earth as seen from space

Answering your weirdest space questions

Could meteorites really rock our world? Is our solar system shaped like a croissant?  Embark on a journey through the cosmos as we answer some of your strangest space questions.

  In the dark?
# THEMARGINALIAN

FROM THE ARCHIVE | The Healing Power of Gardens: Oliver Sacks on the Psychological and Physiological Consolations of Nature

“I work like a gardener,” the great painter Joan Miró wrote in his meditation on the proper pace for creative work. It is hardly a coincidence that Virginia Woolf had her electrifying epiphany about what it means to be an artist while walking amid the flower beds in the garden at St. Ives. Indeed, to garden — even merely to be in a garden — is nothing less than a triumph of resistance against the merciless race of modern life, so compulsively focused on productivity at the cost of creativity, of lucidity, of sanity; a reminder that we are creatures enmeshed with the great web of being, in which, as the great naturalist John Muir observed long ago, “when we try to pick out anything by itself, we find it hitched to everything else in the universe”; a return to what is noblest, which means most natural, in us. There is something deeply humanizing in listening to the rustle of a newly leaved tree, in watching a bumblebee romance a blossom, in kneeling onto the carpet of soil to make a hole for a sapling, gently moving a startled earthworm or two out of the way. Walt Whitman knew this when he weighed what makes life worth living as he convalesced from a paralytic stroke: “After you have exhausted what there is in business, politics, conviviality, love, and so on — have found that none of these finally satisfy, or permanently wear — what remains? Nature remains; to bring out from their torpid recesses, the affinities of a man or woman with the open air, the trees, fields, the changes of seasons — the sun by day and the stars of heaven by night.”/.../

Tenho um motivo adicional ao compartilhar o Prof. Oliver Sachs. Minha irmã Dra. Maria Helena Cechella Achutti - também nonagenária e morando comigo desde o falecimento de minha queria esposa Dra. Valderês - é Farmacêutica e Doutora em Botânica pela Universidade de SP. Ela gosta muito de nosso esforço para manter um jardim em nossa casa, que era desde o início, um dos desejos da cunhada dela.

#IHME

Fine particulate matter exposure increases the risk of developing dementia

Q&A with an expert: Dr. Katrin Burkhart (Assistant Professor at IHME) presents new results that suggest exposure to fine particulate matter (PM2.5) increases the risk of developing all types of dementia.
IHME published a new analysis in Nature Aging to understand the relationship between fine particulate matter (PM2.5) and the risk of developing all types of dementia. The analysis also studied two major subtypes of dementia, Alzheimer’s disease and vascular dementia./.../

The LANCET

National and provincial burden of disease attributable to fine particulate matter air pollution in China, 1990–2021: an analysis of data from the Global Burden of Disease Study 2021


Interpretation

Despite the decline in the disease burden attributable to total PM2·5 in China during 1990–2021, ambient PM2·5 remains a major contributor to mortality and disability. This study highlights considerable spatial heterogeneity across different provinces and provides valuable insights for developing geographically tailored strategies for PM2·5 control and public health promotion in China. Stricter control of ambient air pollution is needed in northern and northwestern regions, while promoting clean cooking energy is more urgently warranted in southwestern areas.

Studying the state of health and disparities to understand trends 

State of health and inequalities among Italian regions. Chart shows "life expectancy at birth"on the y-axis and "year" on the y-axis. Life expectancy at birth in Italy dropped to 82.2 years in 2020 due to COVID-19 and slightly recovered to 82.7 in 2021.

A new study published in The Lancet Public Health analyzed trends and geographical differences
 in disease burden across Italian regions from 2000 to 2021. IHME study authors and collaborators used health metrics to understand how health outcomes differed at national, macro-regional, and subnational levels. 

Studying and understanding the state of health in one country can help inform regional trends. Highlights from this research:
  • Life expectancy at birth in Italy increased from 79.6 years in 2000 to 83.4 years in 2019, dropped to 82.2 years in 2020 due to COVID-19, and recovered slightly to 82.7 in 2021. Healthy life expectancy (HALE) was 70.9 years in 2021.
     
  • Overall, the top causes of years with lived disability (YLDs) were low back pain, falls, and headache disorders. Additionally, anxiety and depressive disorders both had substantial increases from 2019 to 2021 (19.8% and 17.3%, respectively).
     
  • YLDs for Alzheimer’s disease and diabetes increased substantially from 2000 to 2019 and 2019 to 2021 (70.6% and 3.0% for Alzheimer’s disease and 46.8% and 7.9%, for diabetes, respectively, for each timepoint).
Read the research
WST spotted ultraviolet light escaping from the ancient galaxy JADES-GS-z13-1 in the earliest evidence
yet for the "Era of Reionization." © NASA, ESA, CSA, JADES Collaboration, J. Witstok (University of
Cambridge/University of Copenhagen), P. Jakobsen (University of Copenhagen), A. Pagan
(STScI), M. Zamani (ESA/Webb)
Researchers discovered bright ultraviolet (UV) light coming from an ancient,
distant galaxy. The findings, published March 26 in the journal
 Nature,
suggest that the universe's first stars modified their surroundings even
earlier than expected.

Shortly after the Big Bang, the universe was a soup of protons, neutrons and
electrons. As the universe cooled, the protons and neutrons combined to
form positively charged hydrogen ions, which then attracted negatively
charged electrons to create a fog of neutral hydrogen atoms. This fog
absorbed light with short wavelengths, such as UV light, blocking it from
reaching farther into the universe.

But as the first stars and galaxies formed, they emitted enough UV light to
knock the electrons back off the hydrogen atoms, allowing UV light out once
again. Though this "Era of Reionization" is thought to have ended about a
billion years after the Big Bang, scientists still aren't sure exactly when the
first stars formed — or when the Era of Reionization began.

NASA captures first lights turning on in the universe after the Big Bang