BOAS FESTAS!
Non invasive robot control
How to control a robotic arm with your mind — no implanted electrodes requiredDecember 14, 2016 [image: Research subjects at the University of Minnesota fitted with a specialized noninvasive brain cap were able to move the robotic arm just by imagining moving their own arms (credit: College of Science and Engineering)] Researchers at the University of Minnesota have achieved a “major breakthrough” that allows people to control a robotic arm in three dimensions, using only their minds. The research has the potential to help millions of people who are paralyzed or have neurodegenerativ... mais »
metformin prevents, suppresses cancer
How diabetes drug metformin prevents, suppresses cancer growth Ancient genetic pathway suggests new ways to fight cancers and support healthy aging December 16, 2016 [image: Metformin growth inhibition process (credit: Lianfeng Wu et al./Cell)] A team of Massachusetts General Hospital (MGH) and Harvard Medical School investigators has identified a pathway that appears to underlie the apparent ability of the diabetes drug metformin to both block the growth of human cancer cells and extend the lifespan of the *C.elegans* roundworm. That finding implies that this single genetic pathway ma... mais »
aging clock
Cellular reprogramming turns back the aging clock in miceDecember 18, 2016 [image: Turning Back the Aging Clock ft] Salk Institute scientists have extended the average lifespan of live mice by 30 percent, according to a study published December 15 in *Cell*. They did that by rolling back the “aging clock” to younger years, using cellular reprogramming. The finding suggests that *aging is* *reversible *by winding back an animal’s biological clock to a more youthful state and that lifespan can be extended. While the research does not yet apply… read more *Topics:* Biotech Comments (13)
"granulocyte-macrophage colony stimulating factor” (GM-CSF)
Method discovered to remove damaging amyloid plaques found in Alzheimer’s diseaseDecember 23, 2016 [image: Illustration of formation of beta-amyloid plaques. Enzymes act on the APP (amyloid precursor protein) and cut it into fragments. The beta-amyloid fragment is crucial in the formation of senile plaques in Alzheimer’s disease. (credit: National Institute on Aging/NIH)] German scientists have discovered a strategy for removing amyloid plaques — newly forming clumps in a brain with Alzheimer’s disease that are created by misfolded proteins that clump together and damage nerve cells. ... mais »
Retinoic Acide
Supercharged Sprouts Vitamin Inspiration for New Alzheimer’s Drug Research by Neuroscience News Researchers are looking to a supercharged version of retinoic acid, which is derived from sprouts, to help develop new Alzheimer's drugs. Read more of this post *Neuroscience News* | December 23, 2016 at 11:57 am | Tags: retinoic acid, sprouts, vitamin A | URL: http://wp.me/p4sXNK-9MO Comment See all comments
whole-exome sequencing
“Pheno”menal value for human health 1. Daniel J. Rader, 2. Scott M. Damrauer + Author Affiliations 1. Email: rader@mail.med.upenn.edu Science 23 Dec 2016: Vol. 354, Issue 6319, pp. 1534-1536 DOI: 10.1126/science.aal4573 - Article - Figures & Data - Info & Metrics - eLetters - PDF One of the greatest challenges of the biomedical enterprise is to link human genetic variation with phenotypic traits at a population scale. Such efforts have myriad benefits, including the illumination of basic human biology, the early identification of preventable and treatabl... mais »
Non-invasive AD detection
Promising Discovery For A Non-Invasive Early Detection of Alzheimer’sby Neuroscience News A new paper details a technology that can detect pathological oligomeric forms of tau in Alzheimer's patients through human blood platelets. Read more of this post *Neuroscience News* | December 22, 2016 at 12:06 pm | Tags: anterior cingulate gyrus, cerebral volume, fornal cortex, parrahippocampus, tau plateles | URL: http://wp.me/p4sXNK-9Mc Comment See all comments
pimavanserin (Nuplazid)
Promising Topline Results for Pimavanserin in AD Pauline Anderson Medescape: December 22, 2016 EDITORS' RECOMMENDATIONS - FDA Okays Pimavanserin for Hallucinations, Delusions in PD - Alzheimer's Disease News & Perspectives RELATED DRUGS & DISEASES - Alzheimer Disease - Alzheimer Disease in Down Syndrome - Alzheimer Disease Imaging Topline, phase 2 trial results with the antipsychotic drug pimavanserin ( *Nuplazid*, Acadia Pharmaceuticals) in patients with Alzheimer's disease (AD) psychosis showed a statistically significant reduction in psychosis among those taking pima... mais »
Globular Clusters
After the lecture: Astronomer Kelsey Johnson *Reflections on globular clusters, education and our place in the universe* [image: Kelsey Johnson] Kelsey Johnson is an astronomer at the University of Virginia. Credit and Larger Version *December 21, 2016* *University of Virginia astronomer Kelsey Johnson recently delivered a talk titled "How were the most ancient objects in the universe formed?" as part of the National Science Foundation's (NSF) Distinguished Lectures series. NSF's Mathematical and Physical Sciences directorate supports Johnson's work investigating the conditions that g... mais »
Sundowner's Syndrome
Sundowner's Syndrome: Causes, Symptoms, and Treatments A person with sundowner's syndrome experiences increased episodes of confusion, agitation, and activity as the day progresses to night. There may be agitation and personality changes that are dramatically unlike the person's normal behavior. This can be frightening for the individual and their caregiver. While most people are "winding down" or relaxing as the day goes on, those with sundowner's syndrome become increasingly active. Sundowner's syndrome is often associated with dementia, a condition that affects a person's memory, pe... mais »
muscarinic allosteric modulators
M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss, Andrew B. Tobin et al., *Journal of Clinical Investigation*, doi:10.1172/JCI87526, published 19 December 2016. Breakthrough findings demonstrate a possible target and potential drug treatment to restore memory loss and extend life span in mice with neurodegeneration. An international team of scientists has announced a new advance in the fight against Alzheimer's disease by identifying a new drug target for not only improving symptoms of brain degeneration - but also to extend the life-span of ... mais »
Erythema Marginatum
IMAGES IN CLINICAL MEDICINE Acute Rheumatic Fever with Erythema Marginatum Makoto Saito, M.D.Shuji Hatakeyama, M.D., Ph.D. N Engl J Med 2016; 375:2480December 22, 2016DOI: 10.1056/NEJMicm1601782 Share: - Slide ArticleMetrics A previously healthy 36-year-old man presented with a 1-month history of fever and pain in both shoulders and knees, which had been preceded by a sore throat 2 weeks before the onset of fever. Laboratory studies were notable for a white-cell count of 13,800 per cubic millimeter (85% neutrophils), a C-reactive protein level of 26 mg per deciliter (reference va... mais »
SUS
All in a Day’s Work — Equity vs. Equality at a Public ICU in Brazil Flávia R. Machado, Ph.D. N Engl J Med 2016; 375:2420-2421December 22, 2016DOI: 10.1056/NEJMp1610059 Share: ArticleReferencesMetrics “Of all forms of inequality, injustice in health care is the most shocking and most inhumane.” — Martin Luther King, Jr. We begin another day at 7:00 a.m., and once again we need to decide who will get an intensive care unit (ICU) bed after an elective surgical procedure. A 55-year-old grandmother with colon cancer? An elderly man with liver metastases? A young woman suffering from pain w... mais »
DBPOC infecção bacteriana
Terapias antibacterianas contra infecções respiratórias 16/08/2016 Uma investigação conduzida pelo Instituto de Biotecnologia Agrícola (IdAB) identificou, através de uma metodologia pioneira, elementos bacterianos envolvidos na infecção causada por um patógeno que coloniza as vias aéreas de pacientes com DPOC (doença pulmonar obstrutiva crônica). Esta constatação, resultado da colaboração com pesquisadores internacionais das universidades Drexel e Pensilvânia (ambos dos EUA) e British Columbia (da Canadá), permitirá abrir novos caminhos para o desenvolvimento de terapias antibacteria... mais »
Brain Plasticity
The Last Frontier: The Molecular Basis of Brain Plasticity and How Neurons Learnby Neuroscience News A new study proposes a new theory to how neurons learn. Read more of this post *Neuroscience News* | December 21, 2016 at 11:52 am | Tags: brain plsticity , neuroplsaticity, UC Santa Barbara | URL: http://wp.me/p4sXNK-9LS Comment See all comments
Birth Defects: mothers longevity
Mothers of Kids With Severe Birth Defects May Have Shorter Lives: StudyBut the overall risk of early death is still quite low Tuesday, December 20, 2016 [image: HealthDay news image] TUESDAY, Dec. 20, 2016 (HealthDay News) -- A mother raising a child with a major birth defect may face a higher risk of dying early compared with a mother whose child doesn't have a birth defect, Danish research suggests. But, the researchers added, the risk of early death was "marginal." The finding is based on a review involving more than 455,000 Danish mothers. Some had given birth to children with... mais »
US Adults transgender
About 1.3 Million U.S. Adults Identify as Transgender: Study 12/20/2016 04:00 PM EST Survey in 19 states found about 0.5 percent prevalence, with male-to-female cases more common [image: HealthDay news image] Source: HealthDay Related MedlinePlus Page: Gay, Lesbian, Bisexual, and Transgender Health
AD' molecular roots
The Molecular Roots of Alzheimer’s NEUROSCIENCE NEWSDECEMBER 20, 2016 [image: Image shows the structure of TREM2.]*A new study at Washington University School of Medicine in St. Louis details the structure of TREM2, a protein involved in Alzheimer’s disease and other neurodegenerative disorders. Researchers found that mutations associated with Alzheimer’s alter the surface of the protein, while mutations linked to another brain disorder disrupt the protein’s interior. Such alterations may impair TREM2’s normal role in cleaning up cellular waste via a process called phagocytosis. Neur... mais »
Sniff Test
Home Featured Study Confirms Sniff Test May Be Useful in Diagnosing Early Alzheimer’s NEUROSCIENCE NEWSDECEMBER 20, 2016 *Summary: Researchers report the sniff test may be used to diagnose mild cognitive impairment.* *Source: University of Pennsylvania School of Medicine.* *Adds to evidence that decline in sense of smell occurs alongside cognitive decline.* Tests that measure the sense of smell may soon become common in neurologists’ offices. Scientists have been finding increasing evidence that the sense of smell declines sharply in the early stages of Alzheimer’s, and now a new study... mais »
Int. J. Epid.: Stephen Leeder new Editor-in-Chief
Stephen Leeder new Editor-in-Chief of the International Journal of Epidemiology *Stephen Leeder*, Professor of Public Health and Community Medicine at the University of Sydney, Australia, has been appointed Editor-in-Chief of the International Journal of Epidemiology (IJE). He is a longstanding member of IEA and has a wide network of international associations. He was recommended for the post by four past Presidents of IEA. Stephen was Editor-in-Chief of the Medical Journal of Australia in 2013-15. In the 1990s he was President of the Australasian Epidemiological Association and head... mais »
Innovations in HC delivery
Practical innovations in health care delivery Ideas, solutions, and case studies to improve patient care and drive value in your organization. Learn More
M1 muscarinic acetylcholine receptor (M1 mAChR)
NEW DRUG RESTORES MEMORY AND PROLONGS LIFE: MOUSE STUDY *Summary: Researchers have identified a possible new drug target that could help to restore memory loss and improve longevity in Alzheimer’s disease.* *Source: University of Leicester.* *Breakthrough findings demonstrate a possible target and potential drug treatment to restore memory loss and extend life span in mice with neurodegeneration.* *“We have treated mice with a new type of drug, and found that these drugs can not only improve symptoms of brain degeneration, such as cognitive decline, but can also extend the life-span of... mais »
Early Life Social Stress
Early Life Social Stress Has Long Term Impact on Brain Networks: Rat Study NEUROSCIENCE NEWSDECEMBER 19, 2016*Summary:** Findings about how early life social stress affect brain connections in mice may have implications for treating human psychiatric illnesses.* *[image: Image shows connections in the rat brain.]Adult female rats exposed to early life social stress show significant decrease in coordinated neural activity in regions and networksassociated with control of social behavior, stress and depression/anxiety behaviors. (Spheres represent strength of neural activity at rest... mais »
“type 2 innate lymphocytes,” ILC2s
Missing Link Between Gut and Brain Discovered With Big Implications for Diseaseby Neuroscience News Researchers have identified immune cells in the membranes around the brain that could be a 'missing link' in the gut-brain axis. The immune cells also appear to have a positive impact on recovery following spinal cord injury. Read more of this post [image: Image shows immune cells.]*“These cells are potentially the mediator between the gut and the brain. They are the main responder to microbiota changes in the gut. They may go from the gut to the brain, or they may just produce somethi... mais »
Votos de Natal!: Do Professor José Miguel Chatkin
Jose Miguel Chatkin [image: Anexos]10:52 (Há 21 minutos) para mim Meu estimado professor Achutti Ao caro amigo e sua família, envio votos de muitas felicidades e de um bom ano novo, extensivos a todos AMICORs. A este propósito, encaminho em anexo um curto vídeo de canções natalina e de Hanukah (festividade judaica que costuma ocorrer nesta época do ano) gravadas simultaneamente por um padre católico e um rabino em Buenos Aires, reforçando os conceitos de esperança de paz e harmonia entre todos. Abs Chatkin VID-20161212-WA0009 Área de anexos Área de anexos [image: 1457027512704_Un... mais »
Flipboard: 2016
Year in Review 2016 READ MORE SEE YOUR FLIPBOARD ON THE WEB, OR DOWNLOAD THE MOBILE APP
Equity & Health
[image: Equity & Health] [image: Equity & Health] Equity & Health @equitylist FOLLOWS YOU - TWEETS21K - FOLLOWING1,064 - FOLLOWERS29K - LIKES1,873 - LISTS6 - User Actions Following Equity & Health@equitylist FOLLOWS YOU Public Health, Equity and Human Development, Social Determinants of Health news selected by Ruggiero L.
Contribuições à Cardiologia (texto de 2003)
Cardiologia: Contribuições *Depoimento de Aloyzio Cechella Achutti sobre momentos da cardiologia universal, particularmente na prevenção e na dimensão populacional.* * (Texto de 2003 sob título solicitado pelo Dr. Ely Toscano Barbosa, lider e ex-presidente da SBC)* O enorme desenvolvimento que teve a Cardiologia na segunda metade do século XX, foi certamente um motivo de emulação para a busca de uma participação na grande arena universal da especialidade. Ao final da década de 50, enquanto se intensificava o intercâmbio internacional e estagiavam colegas em serv... mais »
Cell cycle control?
*Science* @scienmag 6m6 minutes ago New research paper challenges dogma of cell cycle control http:// scienmag.com/?p=1509321
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