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Summary: Inducing gamma oscillations appears to suppress amyloid production and could prove an effective treatment potential for Alzheimer’s.
Noninvasive technique reduces beta amyloid plaques in mouse models of Alzheimer’s disease.
Using LED lights flickering at a specific frequency, MIT researchers have shown that they can substantially reduce the beta amyloid plaques seen in Alzheimer’s disease, in the visual cortex of mice.
This treatment appears to work by inducing brain waves known as gamma oscillations, which the researchers discovered help the brain suppress beta amyloid production and invigorate cells responsible for destroying the plaques./.../
After an hour of stimulation at 40 hertz, the researchers found a 40 to 50 percent reduction in the levels of beta amyloid proteins in the hippocampus. Stimulation at other frequencies, ranging from 20 to 80 hertz, did not produce this decline. NeuroscienceNews.com image is adapted from the Picower Institute for Learning and Memory video.