Moacyr Scliar: Orla do Guaíba

A nova orla do Guaíba foi entregue à população de Porto Alegre

Restaurante panorâmico na Orla Moacyr Scliar. (Foto: Brayan Martins/PMPA)

29 de junho de 2018 Capa – Caderno 1, Notícias, RS

O Trecho 1 do Parque Urbano da nova orla do Guaíba, batizada de Moacyr Scliar, foi entregue à população de Porto Alegre nesta sexta-feira. Projetado pelo arquiteto Jaime Lerner, autor de inúmeras obras com reconhecimento internacional e um dos cinco urbanistas mais influentes do século 20, a nova área de lazer e contemplação dos porto-alegrenses tem 1,3 quilômetro e fica entre a Usina do Gasômetro e a Rótula das Cuias.

O novo espaço conta com ciclovia e passeio público, mirantes, quadras esportivas, ancoradouro para barcos de passeios turísticos, quatro bares e um restaurante panorâmico. Orçada em 71 milhões de reais, a obra foi executada com recursos do Banco de Desenvolvimento da América Latina.

O prefeito Nelson Marchezan Júnior afirmou que é preciso usufruir e socializar a orla do lago. “Esse é um projeto que vai mudar, vai melhorar a forma como os porto-alegrenses se relacionam com o Guaíba. Esta não é uma obra para um prefeito ou um sindicato. É uma obra para toda a população da cidade usufruir com conforto, segurança e infraestrutura”, destacou. Para o vice-prefeito Gustavo Paim, este projeto vai restabelecer a relação do cidadão com a região. “É o início da mudança da cara de Porto Alegre e da relação do porto-alegrense com o seu cartão postal que é o pôr do sol do Guaíba”, disse.

O ex-prefeito José Fortunati, que estava à frente da prefeitura no início das obras, destacou a importância da continuidade dos projetos para que a população seja beneficiada sempre. “Entregamos hoje para os moradores de Porto Alegre um filho. Um filho com muitos pais, mães, muita gente que trabalhou para que este projeto acontecesse”, lembrou Fortunati. O diretor representante do CAF no Brasil, Jaime Holguín, destacou a importância da parceria com o município. “É uma alegria estar presente numa parceria de uma obra que vai melhorar a qualidade de vida das pessoas e da cidade”, ressaltou Holguín./.../

prevalence induced concept change

The Problem with Solving Problems by Neuroscience News

Researchers say prevalence induced concept changes cause people to redefine problems as they are reduced.

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Perhaps the most socially relevant of the studies described in the paper, Gilbert said, involved participants acting as members of an institutional review board, the committee that reviews research methodology to ensure that scientific studies are ethical. NeuroscienceNews.com image is in the public domain.

Neuroscience News | June 29, 2018 at 6:08 pm | Tags: prevalence induced concept change | URL: https://wp.me/p4sXNK-d39

“Our studies show that people ju

dge each new instance of a concept in the context of the previous instances,” Gilbert said. “So as we reduce the prevalence of a problem, such as discrimination for example, we judge each new behavior in the improved context that we have created.”

“Another way to say this is that solving problems causes us to expand our definitions of them,” he said. “When problems become rare, we count more things as problems. Our studies suggest that when the world gets better, we become harsher critics of it, and this can cause us to mistakenly conclude that it hasn’t actually gotten better at all. Progress, it seems, tends to mask itself.”

Healthy Urban Mobility

MOVING TOWARDS HEALTHIER, MORE EQUITABLE CITIES IN BRAZIL: THE HEALTHY URBAN MOBILITY (HUM) PROJECT

May 24, 2018

Sabrina da Rosa Machry

The Healthy Urban Mobility (HUM) project is entering its final stage. The research aims to find relevant correlations between urban morphology, modes of transport and its effects in individual and collective health, studying the three Brazilian cities of Brasília, Florianópolis and Porto Alegre, along with Oxford, in the United Kingdom.

A video is now available of the preliminary research, including aerial drone footage of the case study areas to illustrate the urban context and some initial footage of field surveys with participants from the communities engaging in walking and cycling in their neighbourhoods. The focus of the project more generally, and its progress so far, are described in more detail below./.../

Internet People

The 25 Most Influential People on the Internet From BTS to Ninja, our list of the 25 most influential people on the internet who had the most impact on social media and the news

BP and Cognition

How High Blood Pressure Hurts Cognition by Neuroscience News

Researchers report impairments in the neuroprotective communication between neural blood vessels, astrocytes and neurons may be an early factor in how high blood pressure may impair cognitive function.

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BRAIN PLASTICITY

FUNDAMENTAL RULE OF BRAIN PLASTICITY DISCOVERED

AD and exosomes

New Mechanism to Explain the Spread of Alzheimer’s Discovered by Neuroscience News Researchers report exosomes help neuron-to-neuron growth and the transfer of oligomer amyloid beta, resulting in apoptosis. The study reveals exosomes may be a primary mediator of the pathogenic progression of Alzheimer's disease. Read more of this post

English reformation

Sometimes circumstances can change rapidly. In the 1520s, an English translation of the Bible by William Tyndale had been deemed heresy. But by the late 1530s, with King Henry VIII's cataclysmic split from the Catholic church, having an English translation of the Bible became not only desirable but mandatory. Its introduction helped usher in a fertile period of English literature, with such luminaries as John Milton, John Bunyan, William Blake, Alfred Tennyson, and eventually William Shakespeare, and also helped fuse the English identity with the Protestant faith:

Germs hidden into the glaciers

And we thought bubonic plague was a thing of the past… There are ancient diseases frozen in glaciers, that if released could cause environmental catastrophe.  Greg Foot reveals all >

World in data

Memorizing these three statistics will help you understand the world

By Max Roser 

| June 26, 2018

One of my favorite websites is OurWorldInData.org. Based at the University of Oxford, it uses statistics—on everything from health and population growth to war, the environment, and energy—to give you phenomenal insight into how living conditions are changing around the world. I asked its founder, Oxford economist Max Roser, to share three facts from the site that everyone should know. Here’s what Max had to say. – Bill Gates/.../

Human Evolution

Recomendado pelo AMICOR Moacyr Saffer 

Are humans still evolving?
By Lucy Jones

To understand our future evolution we need to
look to our past

Will our descendants be cyborgs with hi-tech machine implants, regrowable
limbs and cameras for eyes like something out of a science fiction novel?

Might humans morph into a hybrid species of biological and artificial beings?
Or could we become smaller or taller, thinner or fatter, or even with different
facial features and skin colour?

Of course, we don’t know, but to consider the question, let’s scoot back a
million years to see what humans looked like then. For a start, Homo sapiens
didn’t exist. A million years ago, there were probably a few different species
of humans around, including Homo heidelbergensis, which shared similarities with
both Homo erectus and modern humans, but more primitive anatomy than the
later Neanderthal./.../

Hospital-at-home

Association of a Bundled Hospital-at-Home and 30-Day Postacute Transitional Care Program With Clinical Outcomes and Patient Experiences  

Alex D. Federman, MD, MPH; Tacara Soones, MD, MPH; Linda V. DeCherrie, MD; et al

Invited Commentary: Hospital-at-Home Care Programs—Is the Hospital of the Future at Home?; Joshua M. Liao, MD, MSc; Amol Navathe, MD, PhD; Matthew J. Press, MD, MSc

Alex D. Federman, MD, MPH¹; Tacara Soones, MD, MPH²; Linda V. DeCherrie, MD^1,3; et alBruce Leff, MD⁴; Albert L. Siu, MD, MSPH^3,5

Author Affiliations Article Information

JAMA Intern Med. Published online June 25, 2018. doi:10.1001/jamainternmed.2018.2562

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Association of a Bundled Hospital-at-Home Program With Clinical Outcomes and Patient Experiences

Key Points

Question  What is the association of providing hospital-at-home care bundled with a 30-day postacute period of home-based transitional care with clinical outcomes and patients’ experiences compared with traditional inpatient care?

Findings  This case-control study with 507 participants found that compared with patients receiving inpatient care, patients receiving hospital-at-home care had shorter length of stay; lower rates of 30-day hospital readmission, emergency department visits, and skilled nursing facility admissions; and better ratings of care. There were no differences in the rates of adverse events.

Meaning  Hospital-at-home care bundled with a 30-day episode of postacute transitional care may be a safe and effective alternative to inpatient care for some patients./.../

Melanoma

Association of Hydrochlorothiazide Use With Risk of Malignant Melanoma

Anton Pottegård, MScPharm, PhD¹; Sidsel Arnspang Pedersen, MD^1,2,3; Sigrun Alba Johannesdottir Schmidt, MD, PhD⁴; et alLisbet Rosenkrantz Hölmich, MD, DMSc⁵; Søren Friis, MD^4,6,7; David Gaist, MD, PhD^2,3

Author Affiliations Article Information

JAMA Intern Med. Published online May 29, 2018. doi:10.1001/jamainternmed.2018.1652

We have recently shown that hydrochlorothiazide use increases the risk of lip and nonmelanoma skin cancer, notably squamous cell carcinoma.^1,2 It would have substantial implications if the carcinogenic effect of hydrochlorothiazide also extended to malignant melanoma./...,/

EKG

Screening for Cardiovascular Disease Risk With Electrocardiography

R. Sacha Bhatia, MD, MBA^1,2,3; Paul Dorian, MD, MSc^3,4

Author Affiliations Article Information

JAMA Intern Med. Published online June 12, 2018. doi:10.1001/jamainternmed.2018.2773

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In 1968, Wilson and Jungner¹ outlined the 10 key principles for an ideal screening program. To paraphrase this classic article, a screening program should (1) focus on a common, treatable medical condition; (2) use a suitable, cost-effective test that can accurately detect the condition; and (3) lead to an intervention that can reduce complications of the condition without causing adverse effects by applying the intervention to individuals who will not benefit. Cardiovascular disease (CVD) is a common global problem with effective interventions to mitigate life-threatening complications, particularly in symptomatic patients. However, in asymptomatic patients, interventions, such as revascularization, do not prevent complications. Therefore, our traditional screening tools, namely resting and exercise electrocardiography (ECG), fail to meet the key principles Wilson and Jungner¹ described years ago and should force clinicians to ask hard questions about whether asymptomatic patients should ever be screened for CVD./.../

Tabela Periódica

Inteligência artificial recria a Tabela Periódica dos Elementos sem a ajuda de humanos

Por Natasha Romanzoti, em 26.06.2018

A Tabela Periódica dos Elementos, em sua forma atual, é indiscutivelmente uma das maiores realizações científicas em química.

Os humanos levaram quase um século de tentativa e erro para organizar essa belíssima tabela, mas um novo programa de inteligência artificial (IA) desenvolvido por físicos da Universidade de Stanford (EUA) acabou de realizar o mesmo feito em apenas algumas horas./.../

Edward Gubbon

1787:

British historian Edward Gibbon completed The History of the Decline and Fall of the Roman Empire.

AD and Down S. and Diabetes

Genes Linking Alzheimer’s to Down Syndrome Discovered by Neuroscience News

Researchers report extra copies of genes on chromosome 21 increase Alzheimer's like pathology and cognitive impairment in mouse models of Down syndrome. The findings provide insight into early onset Alzheimer's in those with Down syndrome.

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Scientists are a step closer to understanding which genes are responsible for early onset Alzheimer’s disease in people with Down syndrome, thanks to a new study led by researchers at the Francis Crick Institute and UCL along with an international group of collaborators.

The findings could pave the way for future medicines to prevent the disease in these individuals, and provide insights into the mechanisms that cause dementia in the general population.

Around 1 in 800 people are born with Down syndrome, which arises in people carrying an extra copy of chromosome 21. By the time they reach their 60s, around two thirds of those with Down syndrome will have early onset Alzheimer’s./.../

+++++++++++++++++++++++++++

Insights Into Amyloids Associated with Alzheimer’s and Type 2 Diabetes by Neuroscience News

A new study sheds light on the stabilizing forces of amyloid fibrils associated with Alzheimer's, type 2 diabetes and other neurodegenerative disorders.

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Structures of amyloid fibrils used in the study colored in rainbows to show directionality of amino acids. (a) and (b) microtubule-associated protein tau associated with Alzheimer’s disease (c) amyloid β-peptide associated with Alzheimer’s disease (d) and (e) islet amyloid polypeptide (IAPP) associated with Alzheimer’s disease and type 2 diabetes. NeuroscienceNews.com image is credited to Justin Lemkul.

Câncer Registro

O registro compulsório do câncer agora é lei! A regra, sancionada pelo Presidente da República, vai beneficiar pacientes de câncer em todo o país e trazer dados qualificados para melhorar o manejo da doença. Essa é uma vitória incrível para os pacientes, resultado do trabalho focado da coalisão GoAll, da FEMAMA e de suas ONGs associadas. Estamos muito felizes e gratos por esse momento e por todos que se envolveram com esse objetivo!

Leia mais

FEMAMA Federação Brasileira de Instituições Filantrópicas de Apoio à Saúde da Mama

GBD Neurological Disorders

Oct 8, 2017

Sait Mentes Birlik

added 2 research items from Researchgate

Global, regional, and national burden of neurological disorders during 1990-2015: A systematic analysis for the Global Burden of Disease Study 2015

• 
  Valery Feigin
• 
  Amanuel Abajobir
• 
  Kalkidan Hassen Abate
• [...]
• 
  Theo Vos

Summary Background Comparable data on the global and country-specific burden of neurological disorders and their trends are crucial for health-care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study provides such information but does not routinely aggregate results that are of interest to clinicians specialising in neurological conditions. In this systematic analysis, we quantified the global disease burden due to neurological disorders in 2015 and its relationship with country development level. Methods We estimated global and country-specific prevalence, mortality, disability-adjusted life-years (DALYs), years of life lost (YLLs), and years lived with disability (YLDs) for various neurological disorders that in the GBD classification have been previously spread across multiple disease groupings. The more inclusive grouping of neurological disorders included stroke, meningitis, encephalitis, tetanus, Alzheimer's disease and other dementias, Parkinson's disease, epilepsy, multiple sclerosis, motor neuron disease, migraine, tension-type headache, medication overuse headache, brain and nervous system cancers, and a residual category of other neurological disorders. We also analysed results based on the Socio-demographic Index (SDI), a compound measure of income per capita, education, and fertility, to identify patterns associated with development and how countries fare against expected outcomes relative to their level of development. Findings Neurological disorders ranked as the leading cause group of DALYs in 2015 (250·7 [95% uncertainty interval (UI) 229·1 to 274·7] million, comprising 10·2% of global DALYs) and the second-leading cause group of deaths (9·4 [9·1 to 9·7] million], comprising 16·8% of global deaths). The most prevalent neurological disorders were tension-type headache (1505·9 [UI 1337·3 to 1681·6 million cases]), migraine (958·8 [872·1 to 1055·6] million), medication overuse headache (58·5 [50·8 to 67·4 million]), and Alzheimer's disease and other dementias (46·0 [40·2 to 52·7 million]). Between 1990 and 2015, the number of deaths from neurological disorders increased by 36·7%, and the number of DALYs by 7·4%. These increases occurred despite decreases in age-standardised rates of death and DALYs of 26·1% and 29·7%, respectively; stroke and communicable neurological disorders were responsible for most of these decreases. Communicable neurological disorders were the largest cause of DALYs in countries with low SDI. Stroke rates were highest at middle levels of SDI and lowest at the highest SDI. Most of the changes in DALY rates of neurological disorders with development were driven by changes in YLLs. Interpretation Neurological disorders are an important cause of disability and death worldwide. Globally, the burden of neurological disorders has increased substantially over the past 25 years because of expanding population numbers and ageing, despite substantial decreases in mortality rates from stroke and communicable neurological disorders. The number of patients who will need care by clinicians with expertise in neurological conditions will continue to grow in coming decades. Policy makers and health-care providers should be aware of these trends to provide adequate services. Funding Bill & Melinda Gates Foundation.

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