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Sunday, January 04, 2015

protein without genetic instructions

Protein partially assembles another protein without genetic instructions
January 2, 2015

Protein adds amino acids to a new protein without genetic instructions. The Rqc2 protein (yellow) binds transfer RNAs (dark blue, teal), which add amino acids (bright spot in middle) to a partially made protein (green). The complex binds the ribosome (white). (Credit: anet Iwasa, Ph.D., University of Utah) Defying textbook science, amino acids (the building blocks of a protein) can be assembled by another protein and without genetic instructions, according to a study published today (Jan. 2) in Science. It happens just before an incomplete protein is recycled due to an assembly failure: a protein called Rqc2 prompts ribosomes (which assemble proteins) to … more…

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