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Sunday, June 26, 2016

Coichicine for AF

Colchicine May Reduce One-Year Postablation AF Recurrence

Marlene Busko
February 13, 2014

ATHENS, GREECE — Among patients with paroxysmal atrial fibrillation (AF) who had a single ablation, those who then received a short course of colchicine were less likely to have AF recurrence and more likely to have higher quality of life a year later, researchers report[1].
This study, a planned extension of a three-month trial published earlier, reported by heartwire , was published online Feb 12, 2014, in Heart Rhythm.
The mid-term results from the current study were "impressive," senior author Dr Michael W Cleman (Yale University School of Medicine, New Haven, CT) told heartwire , noting that only six patients needed to be treated to avoid one AF recurrence.
The generic drug colchicine—which has been used "a gazillion years," is approved for gout and familial Mediterranean fever, and has been studied for resistant pericarditis—"seems to be a rather simple and powerful approach to reducing subsequent effects" in people with paroxysmal AF, he continued./.../

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